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Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.
Nat Genet. 1997 Dec;17(4):404-10. doi: 10.1038/ng1297-404.
Nat Genet. 1997.
PMID: 9398841
Genetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesis.
Ryan AB, Zeitlin SO, Scrable H.
Ryan AB, et al.
Neurobiol Dis. 2006 Nov;24(2):419-27. doi: 10.1016/j.nbd.2006.08.002. Epub 2006 Sep 15.
Neurobiol Dis. 2006.
PMID: 16978870
Free PMC article.
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