Evaluation of Biocoat intestinal epithelium differentiation environment (3-day cultured Caco-2 cells) as an absorption screening model with improved productivity

Pharm Res. 1997 Dec;14(12):1835-7. doi: 10.1023/a:1012112820371.

Authors

S Chong¹, S A Dando, R A Morrison

Affiliation

¹ Department of Metabolism and Pharmacokinetics, Bristol-Meyers Squibb Pharmaceutical Research Institute, Princeton, New Jersey 08543-4000, USA.

PMID: 9453077
DOI: 10.1023/a:1012112820371

No abstract available

Publication types

Comparative Study

MeSH terms

Caco-2 Cells*
Cell Membrane Permeability
Culture Media
Drug Evaluation, Preclinical / methods*
Humans
Intestinal Absorption*
Pharmaceutical Preparations / metabolism
Pharmacokinetics*

Substances

Culture Media
Pharmaceutical Preparations