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Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene.
Mol Cell Neurosci. 1998 May;11(1-2):36-46. doi: 10.1006/mcne.1998.0673.
Mol Cell Neurosci. 1998.
PMID: 9608532
Reduced tyrosine hydroxylase and GTP cyclohydrolase mRNA expression, tyrosine hydroxylase activity, and associated neurochemical alterations in Nurr1-null heterozygous mice.
Eells JB, Misler JA, Nikodem VM.
Eells JB, et al.
Brain Res Bull. 2006 Jun 30;70(2):186-95. doi: 10.1016/j.brainresbull.2006.05.004. Epub 2006 May 22.
Brain Res Bull. 2006.
PMID: 16782508
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