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Page 1
Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead.
Bondeson DP, Smith BE, Burslem GM, Buhimschi AD, Hines J, Jaime-Figueroa S, Wang J, Hamman BD, Ishchenko A, Crews CM. Bondeson DP, et al. Among authors: burslem gm. Cell Chem Biol. 2018 Jan 18;25(1):78-87.e5. doi: 10.1016/j.chembiol.2017.09.010. Epub 2017 Nov 9. Cell Chem Biol. 2018. PMID: 29129718 Free PMC article.
The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study.
Burslem GM, Smith BE, Lai AC, Jaime-Figueroa S, McQuaid DC, Bondeson DP, Toure M, Dong H, Qian Y, Wang J, Crew AP, Hines J, Crews CM. Burslem GM, et al. Cell Chem Biol. 2018 Jan 18;25(1):67-77.e3. doi: 10.1016/j.chembiol.2017.09.009. Epub 2017 Nov 9. Cell Chem Biol. 2018. PMID: 29129716 Free PMC article.
Small-Molecule Modulation of Protein Homeostasis.
Burslem GM, Crews CM. Burslem GM, et al. Chem Rev. 2017 Sep 13;117(17):11269-11301. doi: 10.1021/acs.chemrev.7b00077. Epub 2017 Aug 4. Chem Rev. 2017. PMID: 28777566 Review.
Regulation of eDHFR-tagged proteins with trimethoprim PROTACs.
Etersque JM, Lee IK, Sharma N, Xu K, Ruff A, Northrup JD, Sarkar S, Nguyen T, Lauman R, Burslem GM, Sellmyer MA. Etersque JM, et al. Among authors: burslem gm. Nat Commun. 2023 Nov 3;14(1):7071. doi: 10.1038/s41467-023-42820-3. Nat Commun. 2023. PMID: 37923771 Free PMC article.
The chemical biology of ubiquitin.
Burslem GM. Burslem GM. Biochim Biophys Acta Gen Subj. 2022 Mar;1866(3):130079. doi: 10.1016/j.bbagen.2021.130079. Epub 2021 Dec 29. Biochim Biophys Acta Gen Subj. 2022. PMID: 34971772 Free PMC article.
Advances and Opportunities in Epigenetic Chemical Biology.
Beyer JN, Raniszewski NR, Burslem GM. Beyer JN, et al. Among authors: burslem gm. Chembiochem. 2021 Jan 5;22(1):17-42. doi: 10.1002/cbic.202000459. Epub 2020 Sep 24. Chembiochem. 2021. PMID: 32786101 Review.
49 results