PubMed for id: 10295

Year	Number of Results
1990	1
1991	1
1992	1
1996	1
2002	3
2004	3
2005	1
2007	1
2008	1
2009	1
2010	4
2011	5
2014	3
2015	1
2016	7
2017	4
2018	6
2019	6
2020	7
2021	6
2022	9
2023	3
2024	0

1

Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis of colorectal cancer.

Tian Q, Yuan P, Quan C, Li M, Xiao J, Zhang L, Lu H, Ma T, Zou L, Wang F, Xue P, Ni X, Wang W, Liu L, Wang Z, Zhu F, Duan Q. Tian Q, et al. Oncogene. 2020 May;39(20):3980-3996. doi: 10.1038/s41388-020-1262-z. Epub 2020 Apr 1. Oncogene. 2020. PMID: 32238881 Free PMC article.

2

BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer.

Xue P, Zeng F, Duan Q, Xiao J, Liu L, Yuan P, Fan L, Sun H, Malyarenko OS, Lu H, Xiu R, Liu S, Shao C, Zhang J, Yan W, Wang Z, Zheng J, Zhu F. Xue P, et al. EBioMedicine. 2017 Jun;20:50-60. doi: 10.1016/j.ebiom.2017.05.001. Epub 2017 May 4. EBioMedicine. 2017. PMID: 28501528 Free PMC article.

3

Two novel mutations in the BCKDK (branched-chain keto-acid dehydrogenase kinase) gene are responsible for a neurobehavioral deficit in two pediatric unrelated patients.

García-Cazorla A, Oyarzabal A, Fort J, Robles C, Castejón E, Ruiz-Sala P, Bodoy S, Merinero B, Lopez-Sala A, Dopazo J, Nunes V, Ugarte M, Artuch R, Palacín M, Rodríguez-Pombo P, Alcaide P, Navarrete R, Sanz P, Font-Llitjós M, Vilaseca MA, Ormaizabal A, Pristoupilova A, Agulló SB. García-Cazorla A, et al. Hum Mutat. 2014 Apr;35(4):470-7. doi: 10.1002/humu.22513. Epub 2014 Mar 5. Hum Mutat. 2014. PMID: 24449431

4

Regulation of the branched-chain alpha-ketoacid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease.

Harris RA, Zhang B, Goodwin GW, Kuntz MJ, Shimomura Y, Rougraff P, Dexter P, Zhao Y, Gibson R, Crabb DW. Harris RA, et al. Adv Enzyme Regul. 1990;30:245-63. doi: 10.1016/0065-2571(90)90021-s. Adv Enzyme Regul. 1990. PMID: 2403034

5

APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway.

Zhai M, Yang Z, Zhang C, Li J, Jia J, Zhou L, Lu R, Yao Z, Fu Z. Zhai M, et al. Cell Death Dis. 2020 May 26;11(5):396. doi: 10.1038/s41419-020-2610-1. Cell Death Dis. 2020. PMID: 32457292 Free PMC article.

6

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.

White PJ, McGarrah RW, Grimsrud PA, Tso SC, Yang WH, Haldeman JM, Grenier-Larouche T, An J, Lapworth AL, Astapova I, Hannou SA, George T, Arlotto M, Olson LB, Lai M, Zhang GF, Ilkayeva O, Herman MA, Wynn RM, Chuang DT, Newgard CB. White PJ, et al. Cell Metab. 2018 Jun 5;27(6):1281-1293.e7. doi: 10.1016/j.cmet.2018.04.015. Epub 2018 May 17. Cell Metab. 2018. PMID: 29779826 Free PMC article.

7

The plasma levels of CST and BCKDK in patients with sepsis.

Zhang B, Sun GZ, Zhu ML, Li Y, Sun DJ, Zhang B, Bai XP. Zhang B, et al. Peptides. 2016 Dec;86:80-84. doi: 10.1016/j.peptides.2016.10.006. Epub 2016 Oct 20. Peptides. 2016. PMID: 27773658

8

BCKDK regulates breast cancer cell adhesion and tumor metastasis by inhibiting TRIM21 ubiquitinate talin1.

Xu C, Yang K, Xuan Z, Li J, Liu Y, Zhao Y, Zheng Z, Bai Y, Shi Z, Shao C, Zhang L, Sun H. Xu C, et al. Cell Death Dis. 2023 Jul 17;14(7):445. doi: 10.1038/s41419-023-05944-4. Cell Death Dis. 2023. PMID: 37460470 Free PMC article.

9

Tissue-specific translation of murine branched-chain alpha-ketoacid dehydrogenase kinase mRNA is dependent upon an upstream open reading frame in the 5'-untranslated region.

Muller EA, Danner DJ. Muller EA, et al. J Biol Chem. 2004 Oct 22;279(43):44645-55. doi: 10.1074/jbc.M406550200. Epub 2004 Aug 9. J Biol Chem. 2004. PMID: 15302860 Free article.

10

Branched-chain alpha-ketoacid dehydrogenase kinase. Molecular cloning, expression, and sequence similarity with histidine protein kinases.

Popov KM, Zhao Y, Shimomura Y, Kuntz MJ, Harris RA. Popov KM, et al. J Biol Chem. 1992 Jul 5;267(19):13127-30. J Biol Chem. 1992. PMID: 1377677 Free article.

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