PubMed for id: 12229

Year	Number of Results
1972	1
1975	2
1978	1
1979	1
1980	1
1982	2
1983	6
1984	4
1985	6
1986	2
1987	4
1988	2
1990	1
1991	1
1992	5
1993	13
1994	12
1995	16
1996	12
1997	13
1998	9
1999	17
2000	15
2001	11
2002	10
2003	16
2004	23
2005	15
2006	21
2007	18
2008	20
2009	15
2010	14
2011	14
2012	13
2013	16
2014	16
2015	14
2016	13
2017	13
2018	7
2019	10
2020	5
2021	9
2022	4
2023	4
2024	4

1

In BTK, phosphorylated Y223 in the SH3 domain mirrors catalytic activity, but does not influence biological function.

Estupiñán HY, Bouderlique T, He C, Berglöf A, Cappelleri A, Frengen N, Zain R, Karlsson MCI, Månsson R, Smith CIE. Estupiñán HY, et al. Blood Adv. 2024 Apr 23;8(8):1981-1990. doi: 10.1182/bloodadvances.2024012706. Blood Adv. 2024. PMID: 38507738 Free PMC article.

2

Bruton's tyrosine kinase ablation inhibits B cell responses and antibody production for the prevention of chronic rejection in cardiac transplantation.

Han F, Shi X, Liao T, Zhang W, Ma M, Leng Q, Jiang W, Na N, Miao Y, Huang Z. Han F, et al. Clin Immunol. 2024 Apr;261:109941. doi: 10.1016/j.clim.2024.109941. Epub 2024 Feb 15. Clin Immunol. 2024. PMID: 38365047

3

Bruton's tyrosine kinase-bearing B cells and microglia in neuromyelitis optica spectrum disorder.

Liu Y, Huang Z, Zhang TX, Han B, Yang G, Jia D, Yang L, Liu Q, Lau AYL, Paul F, Verkhratsky A, Shi FD, Zhang C. Liu Y, et al. J Neuroinflammation. 2023 Dec 21;20(1):309. doi: 10.1186/s12974-023-02997-2. J Neuroinflammation. 2023. PMID: 38129902 Free PMC article.

4

Loss of B1 and marginal zone B cells during ovarian cancer.

Maslanka J, Torres G, Londregan J, Goldman N, Silberman D, Somerville J, Riggs JE. Maslanka J, et al. Cell Immunol. 2024 Jan-Feb;395-396:104788. doi: 10.1016/j.cellimm.2023.104788. Epub 2023 Nov 22. Cell Immunol. 2024. PMID: 38000306

5

Loss of BTK ameliorates the pathological cardiac fibrosis and dysfunction.

Wang B, Tan Y, Zhou W, Yang J, Jiang Y, Liu X, Zhan Z. Wang B, et al. Matrix Biol. 2022 Sep;112:171-189. doi: 10.1016/j.matbio.2022.08.010. Epub 2022 Aug 27. Matrix Biol. 2022. PMID: 36031013

6

Bruton's Tyrosine Kinase Supports Gut Mucosal Immunity and Commensal Microbiome Recognition in Autoimmune Arthritis.

Bonami RH, Thurman CE, Verma S, Westlake CS, Nyhoff LE, Barron BB, Reboldi A, Kendall PL. Bonami RH, et al. Front Immunol. 2022 Mar 29;13:748284. doi: 10.3389/fimmu.2022.748284. eCollection 2022. Front Immunol. 2022. PMID: 35422819 Free PMC article.

7

Knockout of Bruton's tyrosine kinase in macrophages attenuates diabetic nephropathy in streptozotocin-induced mice.

Fan Z, Li Y, Xia L, Wu Y. Fan Z, et al. Am J Transl Res. 2021 Nov 15;13(11):12352-12363. eCollection 2021. Am J Transl Res. 2021. PMID: 34956457 Free PMC article.

8

Bruton's TK regulates myeloid cell recruitment during acute inflammation.

Purvis GSD, Aranda-Tavio H, Channon KM, Greaves DR. Purvis GSD, et al. Br J Pharmacol. 2022 Jun;179(11):2754-2770. doi: 10.1111/bph.15778. Epub 2022 Mar 15. Br J Pharmacol. 2022. PMID: 34897650 Free PMC article.

9

Bruton's tyrosine kinase drives neuroinflammation and anxiogenic behavior in mouse models of stress.

Ghosh S, Mohammed Z, Singh I. Ghosh S, et al. J Neuroinflammation. 2021 Dec 11;18(1):289. doi: 10.1186/s12974-021-02322-9. J Neuroinflammation. 2021. PMID: 34895246 Free PMC article.

10

X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure.

O'Riordan CE, Purvis GSD, Collotta D, Krieg N, Wissuwa B, Sheikh MH, Ferreira Alves G, Mohammad S, Callender LA, Coldewey SM, Collino M, Greaves DR, Thiemermann C. O'Riordan CE, et al. Front Immunol. 2020 Oct 7;11:581758. doi: 10.3389/fimmu.2020.581758. eCollection 2020. Front Immunol. 2020. PMID: 33162995 Free PMC article.

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