PubMed for id: 12259

Year	Number of Results
1991	1
1996	2
1998	4
1999	4
2000	4
2001	9
2002	9
2003	3
2004	7
2005	10
2006	16
2007	10
2008	13
2009	7
2010	12
2011	18
2012	14
2013	9
2014	13
2015	11
2016	19
2017	16
2018	9
2019	9
2020	18
2021	15
2022	10
2023	8
2024	4

1

Cognitive impairment in Alzheimer's disease FAD^4T mouse model: Synaptic loss facilitated by activated microglia via C1qA.

Zhang C, Qi H, Jia D, Zhao J, Xu C, Liu J, Cui Y, Zhang J, Wang M, Chen M, Tang B. Zhang C, et al. Life Sci. 2024 Mar 1;340:122457. doi: 10.1016/j.lfs.2024.122457. Epub 2024 Jan 23. Life Sci. 2024. PMID: 38266812

2

Complement C1q essential for aeroallergen sensitization via CSF1R⁺ conventional dendritic cells type 2.

Moon HG, Eccles JD, Kim SJ, Kim KH, Kim YM, Rehman J, Lee H, Kanabar P, Christman JW, Ackerman SJ, Ascoli C, Kang H, Choi HS, Kim M, You S, Park GY. Moon HG, et al. J Allergy Clin Immunol. 2023 Nov;152(5):1141-1152.e2. doi: 10.1016/j.jaci.2023.07.016. Epub 2023 Aug 8. J Allergy Clin Immunol. 2023. PMID: 37562753

3

Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation.

Wu X, Gao Y, Shi C, Tong J, Ma D, Shen J, Yang J, Ji M. Wu X, et al. Neuropharmacology. 2023 Oct 1;237:109646. doi: 10.1016/j.neuropharm.2023.109646. Epub 2023 Jun 24. Neuropharmacology. 2023. PMID: 37356797

4

Oligopeptide Transporters of Nonencapsulated Streptococcus pneumoniae Regulate CbpAC and PspA Expression and Reduce Complement-Mediated Clearance.

Thompson CD, Bradshaw JL, Miller WS, Vidal AGJ, Vidal JE, Rosch JW, McDaniel LS, Keller LE. Thompson CD, et al. mBio. 2023 Feb 28;14(1):e0332522. doi: 10.1128/mbio.03325-22. Epub 2023 Jan 10. mBio. 2023. PMID: 36625598 Free PMC article.

5

A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ.

Tang X, Arora G, Matias J, Hart T, Cui Y, Fikrig E. Tang X, et al. Cell Rep. 2022 Nov 22;41(8):111673. doi: 10.1016/j.celrep.2022.111673. Cell Rep. 2022. PMID: 36417869 Free PMC article.

6

Distinct Roles of Classical and Lectin Pathways of Complement in Preeclamptic Placentae.

Belmonte B, Mangogna A, Gulino A, Cancila V, Morello G, Agostinis C, Bulla R, Ricci G, Fraggetta F, Botto M, Garred P, Tedesco F. Belmonte B, et al. Front Immunol. 2022 May 31;13:882298. doi: 10.3389/fimmu.2022.882298. eCollection 2022. Front Immunol. 2022. PMID: 35711467 Free PMC article.

7

Complement protein C1q activates lung fibroblasts and exacerbates silica-induced pulmonary fibrosis in mice.

Ogawa T, Shichino S, Ueha S, Ogawa S, Matsushima K. Ogawa T, et al. Biochem Biophys Res Commun. 2022 May 7;603:88-93. doi: 10.1016/j.bbrc.2022.02.090. Epub 2022 Mar 1. Biochem Biophys Res Commun. 2022. PMID: 35278885

8

C1q inhibits differentiation of oligodendrocyte progenitor cells via Wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis.

Gao Z, Zhang C, Feng Z, Liu Z, Yang Y, Yang K, Chen L, Yao R. Gao Z, et al. Exp Neurol. 2022 Feb;348:113947. doi: 10.1016/j.expneurol.2021.113947. Epub 2021 Dec 10. Exp Neurol. 2022. PMID: 34902359

9

Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury.

Holden SS, Grandi FC, Aboubakr O, Higashikubo B, Cho FS, Chang AH, Forero AO, Morningstar AR, Mathur V, Kuhn LJ, Suri P, Sankaranarayanan S, Andrews-Zwilling Y, Tenner AJ, Luthi A, Aronica E, Corces MR, Yednock T, Paz JT. Holden SS, et al. Science. 2021 Sep 10;373(6560):eabj2685. doi: 10.1126/science.abj2685. Epub 2021 Sep 10. Science. 2021. PMID: 34516796 Free PMC article.

10

Antibodies Elicited in Response to a Single Cycle Glycoprotein D Deletion Viral Vaccine Candidate Bind C1q and Activate Complement Mediated Neutralization and Cytolysis.

Visciano ML, Mahant AM, Pierce C, Hunte R, Herold BC. Visciano ML, et al. Viruses. 2021 Jun 30;13(7):1284. doi: 10.3390/v13071284. Viruses. 2021. PMID: 34209320 Free PMC article.

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