PubMed for id: 18604

Year	Number of Results
1996	1
1998	1
1999	1
2000	2
2001	1
2002	2
2003	1
2004	2
2005	3
2006	1
2008	1
2009	1
2010	1
2011	5
2012	3
2013	4
2014	3
2015	2
2016	5
2018	1
2019	3
2020	3
2021	4
2022	2
2023	2
2024	1

1

Pyruvate Dehydrogenase Kinase 2 Accelerates Endotoxin Shock by Promoting Mitogen-Activated Protein Kinase Activation.

Li C, Dai J, Liu C, Dong G, Zhang X, Zhang J, Yan F, Zhang H, Wang C, Zhao M, Ning Z, Ma Q, Shi H, Li Z, Xiong H. Li C, et al. Inflammation. 2023 Feb;46(1):418-431. doi: 10.1007/s10753-022-01744-8. Epub 2022 Sep 29. Inflammation. 2023. PMID: 36171490

2

PDK2 Deficiency Prevents Ovariectomy-Induced Bone Loss in Mice by Regulating the RANKL-NFATc1 Pathway During Osteoclastogenesis.

Lee JM, Kim MJ, Lee SJ, Kim BG, Choi JY, Lee SM, Ham HJ, Koh JM, Jeon JH, Lee IK. Lee JM, et al. J Bone Miner Res. 2021 Mar;36(3):553-566. doi: 10.1002/jbmr.4202. Epub 2020 Nov 28. J Bone Miner Res. 2021. PMID: 33125772 Free article.

3

Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis.

Go Y, Jeong JY, Jeoung NH, Jeon JH, Park BY, Kang HJ, Ha CM, Choi YK, Lee SJ, Ham HJ, Kim BG, Park KG, Park SY, Lee CH, Choi CS, Park TS, Lee WN, Harris RA, Lee IK. Go Y, et al. Diabetes. 2016 Oct;65(10):2876-87. doi: 10.2337/db16-0223. Epub 2016 Jul 6. Diabetes. 2016. PMID: 27385159

4

Pyruvate dehydrogenase kinase 1 and 2 deficiency reduces high-fat diet-induced hypertrophic obesity and inhibits the differentiation of preadipocytes into mature adipocytes.

Kang HJ, Min BK, Choi WI, Jeon JH, Kim DW, Park S, Lee YK, Kim HJ, Byeon JE, Go Y, Ham HJ, Jeon YH, Kim MJ, Lee JY, Wende AR, Choi SH, Harris RA, Lee IK. Kang HJ, et al. Exp Mol Med. 2021 Sep;53(9):1390-1401. doi: 10.1038/s12276-021-00672-1. Epub 2021 Sep 22. Exp Mol Med. 2021. PMID: 34552205 Free PMC article.

5

Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function.

Yucel N, Wang YX, Mai T, Porpiglia E, Lund PJ, Markov G, Garcia BA, Bendall SC, Angelo M, Blau HM. Yucel N, et al. Cell Rep. 2019 Jun 25;27(13):3939-3955.e6. doi: 10.1016/j.celrep.2019.05.092. Cell Rep. 2019. PMID: 31242425 Free PMC article.

6

Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype.

Min BK, Park S, Kang HJ, Kim DW, Ham HJ, Ha CM, Choi BJ, Lee JY, Oh CJ, Yoo EK, Kim HE, Kim BG, Jeon JH, Hyeon DY, Hwang D, Kim YH, Lee CH, Lee T, Kim JW, Choi YK, Park KG, Chawla A, Lee J, Harris RA, Lee IK. Min BK, et al. Front Immunol. 2019 May 7;10:944. doi: 10.3389/fimmu.2019.00944. eCollection 2019. Front Immunol. 2019. PMID: 31134063 Free PMC article.

7

Pyruvate dehydrogenase kinase 2 and 4 gene deficiency attenuates nociceptive behaviors in a mouse model of acute inflammatory pain.

Jha MK, Rahman MH, Park DH, Kook H, Lee IK, Lee WH, Suk K. Jha MK, et al. J Neurosci Res. 2016 Sep;94(9):837-49. doi: 10.1002/jnr.23727. Epub 2016 Mar 1. J Neurosci Res. 2016. PMID: 26931482

8

Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis.

Jha MK, Song GJ, Lee MG, Jeoung NH, Go Y, Harris RA, Park DH, Kook H, Lee IK, Suk K. Jha MK, et al. J Neurosci. 2015 Oct 21;35(42):14353-69. doi: 10.1523/JNEUROSCI.1910-15.2015. J Neurosci. 2015. PMID: 26490872 Free PMC article.

9

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance.

Rahimi Y, Camporez JP, Petersen MC, Pesta D, Perry RJ, Jurczak MJ, Cline GW, Shulman GI. Rahimi Y, et al. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16508-13. doi: 10.1073/pnas.1419104111. Epub 2014 Nov 3. Proc Natl Acad Sci U S A. 2014. PMID: 25368185 Free PMC article.

10

Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease.

Harris PC, Torres VE. Harris PC, et al. J Clin Invest. 2014 Jun;124(6):2315-24. doi: 10.1172/JCI72272. Epub 2014 Jun 2. J Clin Invest. 2014. PMID: 24892705 Free PMC article. Review.

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