PubMed for id: 20274

Year	Number of Results
1993	1
1996	2
1997	1
1999	1
2000	2
2001	1
2002	2
2004	3
2005	4
2006	1
2007	1
2008	1
2009	2
2011	5
2012	5
2013	7
2014	6
2015	1
2016	3
2017	4
2018	3
2019	3
2020	3
2021	3
2022	4
2023	4
2024	1

1

Nav1.7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids.

Deng L, Dourado M, Reese RM, Huang K, Shields SD, Stark KL, Maksymetz J, Lin H, Kaminker JS, Jung M, Foreman O, Tao J, Ngu H, Joseph V, Roose-Girma M, Tam L, Lardell S, Orrhult LS, Karila P, Allard J, Hackos DH. Deng L, et al. Neuron. 2023 Sep 6;111(17):2642-2659.e13. doi: 10.1016/j.neuron.2023.05.024. Epub 2023 Jun 22. Neuron. 2023. PMID: 37352856 Free article.

2

Na_v1.7 gain-of-function mutation I228M triggers age-dependent nociceptive insensitivity and C-LTMR dysregulation.

Wimalasena NK, Taub DG, Shim J, Hakim S, Kawaguchi R, Chen L, El-Rifai M, Geschwind DH, Dib-Hajj SD, Waxman SG, Woolf CJ. Wimalasena NK, et al. Exp Neurol. 2023 Jun;364:114393. doi: 10.1016/j.expneurol.2023.114393. Epub 2023 Mar 30. Exp Neurol. 2023. PMID: 37003485 Free PMC article.

3

Examination of the contribution of Nav1.7 to axonal propagation in nociceptors.

Goodwin G, McMurray S, Stevens EB, Denk F, McMahon SB. Goodwin G, et al. Pain. 2022 Jul 1;163(7):e869-e881. doi: 10.1097/j.pain.0000000000002490. Epub 2021 Sep 23. Pain. 2022. PMID: 34561392

4

Dissecting the precise nature of itch-evoked scratching.

Wimalasena NK, Milner G, Silva R, Vuong C, Zhang Z, Bautista DM, Woolf CJ. Wimalasena NK, et al. Neuron. 2021 Oct 6;109(19):3075-3087.e2. doi: 10.1016/j.neuron.2021.07.020. Epub 2021 Aug 18. Neuron. 2021. PMID: 34411514 Free PMC article.

5

Two independent mouse lines carrying the Nav1.7 I228M gain-of-function variant display dorsal root ganglion neuron hyperexcitability but a minimal pain phenotype.

Chen L, Wimalasena NK, Shim J, Han C, Lee SI, Gonzalez-Cano R, Estacion M, Faber CG, Lauria G, Dib-Hajj SD, Woolf CJ, Waxman SG. Chen L, et al. Pain. 2021 Jun 1;162(6):1758-1770. doi: 10.1097/j.pain.0000000000002171. Pain. 2021. PMID: 33323889 Free PMC article.

6

Sensory neuron-derived Na_V1.7 contributes to dorsal horn neuron excitability.

Alles SRA, Nascimento F, Luján R, Luiz AP, Millet Q, Bangash MA, Santana-Varela S, Zhou X, Cox JJ, Okorokov AL, Beato M, Zhao J, Wood JN. Alles SRA, et al. Sci Adv. 2020 Feb 19;6(8):eaax4568. doi: 10.1126/sciadv.aax4568. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128393 Free PMC article.

7

3'-O-Methylorobol Inhibits the Voltage-Gated Sodium Channel Nav1.7 with Anti-Itch Efficacy in A Histamine-Dependent Itch Mouse Model.

Zhang F, Wu Y, Xue S, Wang S, Zhang C, Cao Z. Zhang F, et al. Int J Mol Sci. 2019 Dec 1;20(23):6058. doi: 10.3390/ijms20236058. Int J Mol Sci. 2019. PMID: 31805638 Free PMC article.

8

Insensitivity to Pain upon Adult-Onset Deletion of Nav1.7 or Its Blockade with Selective Inhibitors.

Shields SD, Deng L, Reese RM, Dourado M, Tao J, Foreman O, Chang JH, Hackos DH. Shields SD, et al. J Neurosci. 2018 Nov 21;38(47):10180-10201. doi: 10.1523/JNEUROSCI.1049-18.2018. Epub 2018 Oct 9. J Neurosci. 2018. PMID: 30301756 Free PMC article.

9

Mapping protein interactions of sodium channel Na_V1.7 using epitope-tagged gene-targeted mice.

Kanellopoulos AH, Koenig J, Huang H, Pyrski M, Millet Q, Lolignier S, Morohashi T, Gossage SJ, Jay M, Linley JE, Baskozos G, Kessler BM, Cox JJ, Dolphin AC, Zufall F, Wood JN, Zhao J. Kanellopoulos AH, et al. EMBO J. 2018 Feb 1;37(3):427-445. doi: 10.15252/embj.201796692. Epub 2018 Jan 15. EMBO J. 2018. PMID: 29335280 Free PMC article.

10

NaV1.7 and pain: contribution of peripheral nerves.

Hoffmann T, Sharon O, Wittmann J, Carr RW, Vyshnevska A, Col R, Nassar MA, Reeh PW, Weidner C. Hoffmann T, et al. Pain. 2018 Mar;159(3):496-506. doi: 10.1097/j.pain.0000000000001119. Pain. 2018. PMID: 29194125 Free article.

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