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36372157,28721437,28302472,24948367,23042098,22303456,22262639,21451356,20971161,20223923,19920141,19413500,18675888,18595723,18479823,18227838,18088369,17712345,17348861,17082637,16782007,16670284,16510590,16407894,15950773,15677498,12551961,12134156,12062026,11160759,10051434,8424957,7592886,1717989,37999644,35054890,31842849,31805372,31413238,30583000,30142376,29332129,27934942,27666485,27629357,27528403,27035884,26566650,26336156,26296889,26151480,26109671,25993696,25971971,25617223,25605336,25526308,24905940,24704674,23993963,23793953,23732116,23643895,23620016,23444405,22269103,22232579,22156655,22002869,21961044,21705143,21683092,21586567,21570469,21546758,21530063,21463687,21334310,21248139,21118399,21074569,21056559,20953578,20950336,20922792,20739576,20696763,20590408,20589721,20576526,20558733,20558133,20540975,20404333,20368360,20186879,20074457,20012228,19914607,19801509,19762761,19619605,19565657,19372235,19286961,19130938,19120149,19041135,18973551,18948401,18768839,18717733,18438911,18291742,18287965,18234473,18180375,18056041,17967895,17727840,17709754,17641779,17613254,17418417,17022980,16979915,16943367,16867183,16863646,16820883,16805921,16785500,16670283,16621802,16616413,16504549,16226508,16081808,15901735,15797923,15502830,15456767,15132979,15096454,14997210,14715940,12921749,12647296,12477973,12218045,12042309,11923207,11830463,11789669,9415407,9087672,8108135,7997269,7797459,7619503,7592946,6966611,1716439,36792609,36087811,35849954,34936222,34718327,34709510,34520454,34047289,33607074,32990679,31877781,31513306,31270345,30803445,30342227,29789577,29668927,29373150,29331377,29300908,29242588,28797761,28733355,28723692,28709835,28608568,28535663,28338993,28218391,28119463,27998643,27995734,27993988,27470585,27317946,27256374,26974158,26935534,26565022,26235619,26165762,25937275,25757564,25609615,25592043,25533346,25362112,25222560,24872319,24608673,24603862,24272970,24259565,24012986,23977192,23933734,23842752,23293787,23221339,23123966,23078124,22956616,22927911,22814289,22733812,22579611,22309999,22285818,22021337,21947782,21838783,21780113,21731758,21606113,21493702,21471251,21320173,21146630,21127295,21085672,20849821,20738258,20736313,20680516,20650883,20410673,20408896,20399747,20361273,20304052,20212170,20194602,20154642,19843578,19804826,19628583,19500499,19443782,19298784,19277491,19259952,19228841,19228106,19221709,19166300,19041940,18940914,18838616,18823499,18703672,18644622,18637712,18606697,18579743,18406464,18321244,18305402,18205703,18196969,18060741,17914071,17785185,17662968,17660198,17660197,17337702,17314319,17268885,17068135,17015703,16972271,16920919,16916926,16914058,16857343,16808899,16778140,16730415,16554472,15629424,15572037,15169786,15166036,15020650,14701865,14670631,14605001,14597424,14568551,12955074,12920127,12718435,12097372,11756441,10558995,9421269,8896447,8706129,38117455,37968726,37301443,36979407,34779126,34433058,33344654,32917360,32697984,32017927,31519471,30837304,30626485,30562644,30481403,29276985,29268268,29249667,29106539,29038159,28961951,28623179,28428003,28420753,28389562,28142259,27878722,27778412,27738712,27662443,27468693,27187615,27034231,26835742,26830449,26408092,26206316,26168033,25810299,25657047,25635057,25283357,25267105,25227984,25181481,25060812,24920040,24878634,24657659,24463270,24247009,24184684,24053798,23991041,23599344,23589880,23575844,23252577,23205673,23070543,22917644,22912494,22902213,22784206,22745486,22675204,22593579,22564616,22551942,22049075,22022520,22005268,21997487,21947361,21931742,21914493,21802073,21730055,21618584,21559295,21493863,21445983,21364650,21248107,21177758,21135229,21115804,21084617,21047912,20889126,20832397,20817051,20564184,20513439,20503384,20372827,19917879,19835973,19766642,19728154,19667175,19661066,19521792,19469902,19419315,19321450,19279269,19249353,19243475,19177593,19176891,19166809,19164294,19151789,19147767,19117954,19074677,19017950,18838072,18753132,18635668,18596216,18492489,18435914,18434625,18328346,18295889,18294630,18258819,18158318,17989209,17694057,17664275,17582742,17482686,17463321,17077290,16950125,16888810,16723511,16434965,16207820,16126724,16020276,15964803,15899793,15814736,15809051,15686869,15537893,15155620,15107845,14718391,14673008,14634061,14597699,14566055,14506249,14501944,12810726,12629153,12612072,12393886,12270934,11726647,11684667,9149902,37951191,37636062,34199092,33690225,33235206,31196980,30761608,29018280,28934393,28919206,28199510,27910070,26985001,26814233,26565025,25885040,25319133,24938188,24647208,24495410,24486509,24213576,24155087,23664424,23362023,22988300,22869729,22733747,22532587,22393041,22203480,22174878,22130674,22053946,22053056,21903164,21896736,21505187,21427409,21256191,20933598,20710027,20478381,20304828,20188141,20123980,20011526,20004665,19801662,19524014,19483086,19448628,19377069,19265198,19199341,19074139,18840457,18702304,18651635,18641057,18468454,18456735,18327788,18316486,18080100,18061203,18048358,18036345,17606625,174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Proteomic characterization of spinal cord synaptoneurosomes from Tg-SOD1/G93A mice supports a role for MNK1 and local translation in the early stages of amyotrophic lateral sclerosis.

Casañas JJ, Montesinos ML. Casañas JJ, et al. Mol Cell Neurosci. 2022 Dec;123:103792. doi: 10.1016/j.mcn.2022.103792. Epub 2022 Nov 11. Mol Cell Neurosci. 2022. PMID: 36372157 Free article.

ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB.

Leduc M, Richard J, Costes S, Muller D, Varrault A, Compan V, Mathieu J, Tanti JF, Pagès G, Pouyssegur J, Bertrand G, Dalle S, Ravier MA. Leduc M, et al. Diabetologia. 2017 Oct;60(10):1999-2010. doi: 10.1007/s00125-017-4356-6. Epub 2017 Jul 18. Diabetologia. 2017. PMID: 28721437 Free article.

ERK1 and ERK2 activation modulates diet-induced obesity in mice.

Khan AS, Subramaniam S, Dramane G, Khelifi D, Khan NA. Khan AS, et al. Biochimie. 2017 Jun;137:78-87. doi: 10.1016/j.biochi.2017.03.004. Epub 2017 Mar 14. Biochimie. 2017. PMID: 28302472

ERK1/2 antagonize AMPK-dependent regulation of FcεRI-mediated mast cell activation and anaphylaxis.

Hwang SL, Lu Y, Li X, Kim YD, Cho YS, Jahng Y, Son JK, Lee YJ, Kang W, Taketomi Y, Murakami M, Moon TC, Chang HW. Hwang SL, et al. J Allergy Clin Immunol. 2014 Sep;134(3):714-721.e7. doi: 10.1016/j.jaci.2014.05.001. Epub 2014 Jun 17. J Allergy Clin Immunol. 2014. PMID: 24948367

MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells.

Guégan JP, Ezan F, Théret N, Langouët S, Baffet G. Guégan JP, et al. Carcinogenesis. 2013 Jan;34(1):38-47. doi: 10.1093/carcin/bgs317. Epub 2012 Oct 5. Carcinogenesis. 2013. PMID: 23042098

ERK1 regulates the hematopoietic stem cell niches.

Saulnier N, Guihard S, Holy X, Decembre E, Jurdic P, Clay D, Feuillet V, Pagès G, Pouysségur J, Porteu F, Gaudry M. Saulnier N, et al. PLoS One. 2012;7(1):e30788. doi: 10.1371/journal.pone.0030788. Epub 2012 Jan 30. PLoS One. 2012. PMID: 22303456 Free PMC article.

ERK1 is important for Th2 differentiation and development of experimental asthma.

Goplen N, Karim Z, Guo L, Zhuang Y, Huang H, Gorska MM, Gelfand E, Pagés G, Pouysségur J, Alam R. Goplen N, et al. FASEB J. 2012 May;26(5):1934-45. doi: 10.1096/fj.11-196477. Epub 2012 Jan 18. FASEB J. 2012. PMID: 22262639 Free PMC article.

Rapid activation of phosphorylated mitogen-activated protein kinase after sexual stimulation in male mice.

Taziaux M, Keller M, Balthazart J, Bakker J. Taziaux M, et al. Neuroreport. 2011 Apr 20;22(6):294-8. doi: 10.1097/WNR.0b013e3283460f35. Neuroreport. 2011. PMID: 21451356 Free PMC article.

A role for extracellular signal-regulated kinases 1 and 2 in the maintenance of persistent mechanical hyperalgesia in ovariectomized mice.

Klinger MB, Sacks S, Cervero F. Klinger MB, et al. Neuroscience. 2011 Jan 13;172:483-93. doi: 10.1016/j.neuroscience.2010.10.043. Epub 2010 Oct 31. Neuroscience. 2011. PMID: 20971161

The MAPK ERK1 is a negative regulator of the adult steady-state splenic erythropoiesis.

Guihard S, Clay D, Cocault L, Saulnier N, Opolon P, Souyri M, Pagès G, Pouysségur J, Porteu F, Gaudry M. Guihard S, et al. Blood. 2010 May 6;115(18):3686-94. doi: 10.1182/blood-2009-09-242487. Epub 2010 Mar 11. Blood. 2010. PMID: 20223923 Free article.

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