PubMed for id: 266632

Year	Number of Results
1999	1
2000	2
2001	2
2002	4
2003	5
2004	2
2005	6
2006	4
2007	8
2008	11
2009	11
2010	2
2011	7
2012	6
2013	7
2014	6
2015	3
2016	7
2017	5
2018	4
2019	2
2020	1
2021	2
2022	3
2024	1

1

The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection.

Pereira M, Ramalho T, Andrade WA, Durso DF, Souza MC, Fitzgerald KA, Golenbock DT, Silverman N, Gazzinelli RT. Pereira M, et al. Cell Rep. 2024 Feb 27;43(2):113795. doi: 10.1016/j.celrep.2024.113795. Epub 2024 Feb 15. Cell Rep. 2024. PMID: 38367238 Free article.

2

Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion.

Picard A, Berney X, Castillo-Armengol J, Tarussio D, Jan M, Sanchez-Archidona AR, Croizier S, Thorens B. Picard A, et al. Mol Metab. 2022 Jul;61:101479. doi: 10.1016/j.molmet.2022.101479. Epub 2022 Mar 24. Mol Metab. 2022. PMID: 35339728 Free PMC article.

3

IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma.

Somani VK, Zhang D, Dodhiawala PB, Lander VE, Liu X, Kang LI, Chen HP, Knolhoff BL, Li L, Grierson PM, Ruzinova MB, DeNardo DG, Lim KH. Somani VK, et al. Gastroenterology. 2022 Jun;162(7):2047-2062. doi: 10.1053/j.gastro.2022.02.035. Epub 2022 Mar 7. Gastroenterology. 2022. PMID: 35271824 Free PMC article.

4

Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors.

Tanaka Y, Takeda R, Fukushima T, Mikami K, Tsuchiya S, Tamura M, Adachi K, Umemoto T, Asada S, Watanabe N, Morishita S, Imai M, Nagata M, Araki M, Takizawa H, Fukuyama T, Lamagna C, Masuda ES, Ito R, Goyama S, Komatsu N, Takaku T, Kitamura T. Tanaka Y, et al. Nat Commun. 2022 Jan 12;13(1):271. doi: 10.1038/s41467-021-27928-8. Nat Commun. 2022. PMID: 35022428 Free PMC article.

5

USP13-mediated IRAK4 deubiquitination disrupts the pathological symptoms of lipopolysaccharides-induced sepsis.

Wang Z, Jiang L, Zhang D, Chen D, Wang L, Xiao D. Wang Z, et al. Microbes Infect. 2021 Nov-Dec;23(9-10):104867. doi: 10.1016/j.micinf.2021.104867. Epub 2021 Jul 21. Microbes Infect. 2021. PMID: 34298177 Free article.

6

MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling.

Deliz-Aguirre R, Cao F, Gerpott FHU, Auevechanichkul N, Chupanova M, Mun Y, Ziska E, Taylor MJ. Deliz-Aguirre R, et al. J Cell Biol. 2021 Jul 5;220(7):e202012071. doi: 10.1083/jcb.202012071. Epub 2021 May 6. J Cell Biol. 2021. PMID: 33956941 Free PMC article.

7

The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells.

Corzo CA, Varfolomeev E, Setiadi AF, Francis R, Klabunde S, Senger K, Sujatha-Bhaskar S, Drobnick J, Do S, Suto E, Huang Z, Eastham-Anderson J, Katewa A, Pang J, Domeyer M, Dela Cruz C, Paler-Martinez A, Lau VWC, Hadadianpour A, Ramirez-Carrozi V, Sun Y, Bao K, Xu D, Hunley E, Brightbill HD, Warming S, Roose-Girma M, Wong A, Tam L, Emson CL, Crawford JJ, Young WB, Pappu R, McKenzie BS, Asghari V, Vucic D, Hackney JA, Austin CD, Lee WP, Lekkerkerker A, Ghilardi N, Bryan MC, Kiefer JR, Townsend MJ, Zarrin AA. Corzo CA, et al. Sci Signal. 2020 Jun 2;13(634):eaaz1053. doi: 10.1126/scisignal.aaz1053. Sci Signal. 2020. PMID: 32487715

8

IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colorectal cancer.

Li Q, Chen Y, Zhang D, Grossman J, Li L, Khurana N, Jiang H, Grierson PM, Herndon J, DeNardo DG, Challen GA, Liu J, Ruzinova MB, Fields RC, Lim KH. Li Q, et al. JCI Insight. 2019 Oct 3;4(19):e130867. doi: 10.1172/jci.insight.130867. JCI Insight. 2019. PMID: 31527315 Free PMC article.

9

Nod1-mediated lipolysis promotes diacylglycerol accumulation and successive inflammation via PKCδ-IRAK axis in adipocytes.

Sharma A, Maurya CK, Arha D, Rai AK, Singh S, Varshney S, Schertzer JD, Tamrakar AK. Sharma A, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):136-146. doi: 10.1016/j.bbadis.2018.10.036. Epub 2018 Nov 2. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30391544 Free article.

10

Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins.

Ippagunta SK, Pollock JA, Sharma N, Lin W, Chen T, Tawaratsumida K, High AA, Min J, Chen Y, Guy RK, Redecke V, Katzenellenbogen JA, Häcker H. Ippagunta SK, et al. Sci Signal. 2018 Aug 14;11(543):eaaq1077. doi: 10.1126/scisignal.aaq1077. Sci Signal. 2018. PMID: 30108181 Free PMC article.

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