PubMed for id: 69071

Year	Number of Results
1995	2
1996	1
1999	1
2000	4
2001	2
2002	2
2003	1
2004	1
2005	2
2011	2
2013	1
2014	1
2016	1
2017	1
2020	3
2021	3
2022	2
2023	1
2024	2

1

Highly specific σ₂R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response.

Yousuf MS, Sahn JJ, Yang H, David ET, Shiers S, Mancilla Moreno M, Iketem J, Royer DM, Garcia CD, Zhang J, Hong VM, Mian SM, Ahmad A, Kolber BJ, Liebl DJ, Martin SF, Price TJ. Yousuf MS, et al. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2306090120. doi: 10.1073/pnas.2306090120. Epub 2023 Dec 20. Proc Natl Acad Sci U S A. 2023. PMID: 38117854 Free PMC article.

2

σ₂R/TMEM97 in retinal ganglion cell degeneration.

Wang H, Peng Z, Li Y, Sahn JJ, Hodges TR, Chou TH, Liu Q, Zhou X, Jiao S, Porciatti V, Liebl DJ, Martin SF, Wen R. Wang H, et al. Sci Rep. 2022 Dec 1;12(1):20753. doi: 10.1038/s41598-022-24537-3. Sci Rep. 2022. PMID: 36456686 Free PMC article.

3

TMEM97 ablation aggravates oxidant-induced retinal degeneration.

Shen H, Li J, Heisler-Taylor T, Makin R, Yang H, Mavlyutov TA, Gelfand B, Cebulla CM, Guo LW. Shen H, et al. Cell Signal. 2021 Oct;86:110078. doi: 10.1016/j.cellsig.2021.110078. Epub 2021 Jul 7. Cell Signal. 2021. PMID: 34245862 Free PMC article.

4

The Sigma-2 receptor / transmembrane protein 97 (σ2R/TMEM97) modulator JVW-1034 reduces heavy alcohol drinking and associated pain states in male mice.

Quadir SG, Tanino SM, Rohl CD, Sahn JJ, Yao EJ, Cruz LDR, Cottone P, Martin SF, Sabino V. Quadir SG, et al. Neuropharmacology. 2021 Feb 15;184:108409. doi: 10.1016/j.neuropharm.2020.108409. Epub 2020 Nov 20. Neuropharmacology. 2021. PMID: 33221481 Free PMC article.

5

Transmembrane protein TMEM97 and epigenetic reader BAHCC1 constitute an axis that supports pro-inflammatory cytokine expression.

Li J, Shen H, Guo LW. Li J, et al. Cell Signal. 2024 Apr;116:111069. doi: 10.1016/j.cellsig.2024.111069. Epub 2024 Jan 28. Cell Signal. 2024. PMID: 38290642

6

Differential Responses to Sigma-1 or Sigma-2 Receptor Ablation in Adiposity, Fat Oxidation, and Sexual Dimorphism.

Li J, Félix-Soriano E, Wright KR, Shen H, Baer LA, Stanford KI, Guo LW. Li J, et al. Int J Mol Sci. 2022 Sep 16;23(18):10846. doi: 10.3390/ijms231810846. Int J Mol Sci. 2022. PMID: 36142759 Free PMC article.

7

Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in Mice.

Sahn JJ, Mejia GL, Ray PR, Martin SF, Price TJ. Sahn JJ, et al. ACS Chem Neurosci. 2017 Aug 16;8(8):1801-1811. doi: 10.1021/acschemneuro.7b00200. Epub 2017 Jul 13. ACS Chem Neurosci. 2017. PMID: 28644012 Free PMC article.

8

The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception.

Sánchez-Blázquez P, Cortés-Montero E, Rodríguez-Muñoz M, Merlos M, Garzón-Niño J. Sánchez-Blázquez P, et al. Mol Brain. 2020 Nov 11;13(1):150. doi: 10.1186/s13041-020-00676-4. Mol Brain. 2020. PMID: 33176836 Free PMC article.

9

A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes.

Cheng YS, Zhang T, Ma X, Pratuangtham S, Zhang GC, Ondrus AA, Mafi A, Lomenick B, Jones JJ, Ondrus AE. Cheng YS, et al. Nat Chem Biol. 2021 Dec;17(12):1271-1280. doi: 10.1038/s41589-021-00907-2. Epub 2021 Nov 19. Nat Chem Biol. 2021. PMID: 34799735 Free PMC article.

10

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans.

Mink M, Fogelgren B, Olszewski K, Maroy P, Csiszar K. Mink M, et al. Genomics. 2001 Jun 1;74(2):234-44. doi: 10.1006/geno.2001.6548. Genomics. 2001. PMID: 11386760

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