PubMed (OMIM) for id: 4005

Year	Number of Results
1985	2
1986	1
1991	2
1995	1
1997	3
1998	1
1999	1
2000	1
2003	2
2004	4
2005	2
2006	1
2007	1
2010	2
2024	0

1

A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients.

Oram SH, Thoms JA, Pridans C, Janes ME, Kinston SJ, Anand S, Landry JR, Lock RB, Jayaraman PS, Huntly BJ, Pimanda JE, Göttgens B. Oram SH, et al. Oncogene. 2010 Oct 28;29(43):5796-808. doi: 10.1038/onc.2010.320. Epub 2010 Aug 2. Oncogene. 2010. PMID: 20676125 Free article.

2

The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal.

McCormack MP, Young LF, Vasudevan S, de Graaf CA, Codrington R, Rabbitts TH, Jane SM, Curtis DJ. McCormack MP, et al. Science. 2010 Feb 12;327(5967):879-83. doi: 10.1126/science.1182378. Epub 2010 Jan 21. Science. 2010. PMID: 20093438

3

The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas.

Natkunam Y, Zhao S, Mason DY, Chen J, Taidi B, Jones M, Hammer AS, Hamilton Dutoit S, Lossos IS, Levy R. Natkunam Y, et al. Blood. 2007 Feb 15;109(4):1636-42. doi: 10.1182/blood-2006-08-039024. Epub 2006 Oct 12. Blood. 2007. PMID: 17038524 Free PMC article.

4

Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex.

Han C, Liu H, Liu J, Yin K, Xie Y, Shen X, Wang Y, Yuan J, Qiang B, Liu YJ, Peng X. Han C, et al. Nucleic Acids Res. 2005 Nov 24;33(20):6555-65. doi: 10.1093/nar/gki964. Print 2005. Nucleic Acids Res. 2005. PMID: 16314316 Free PMC article.

5

Fli1, Elf1, and Ets1 regulate the proximal promoter of the LMO2 gene in endothelial cells.

Landry JR, Kinston S, Knezevic K, Donaldson IJ, Green AR, Göttgens B. Landry JR, et al. Blood. 2005 Oct 15;106(8):2680-7. doi: 10.1182/blood-2004-12-4755. Epub 2005 Jun 30. Blood. 2005. PMID: 15994290 Free article.

6

Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes.

Lossos IS, Czerwinski DK, Alizadeh AA, Wechser MA, Tibshirani R, Botstein D, Levy R. Lossos IS, et al. N Engl J Med. 2004 Apr 29;350(18):1828-37. doi: 10.1056/NEJMoa032520. N Engl J Med. 2004. PMID: 15115829 Free article.

7

Good news for gene therapy.

Berns A. Berns A. N Engl J Med. 2004 Apr 15;350(16):1679-80. doi: 10.1056/NEJMcibr040341. N Engl J Med. 2004. PMID: 15084702 No abstract available.

8

Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency.

McCormack MP, Rabbitts TH. McCormack MP, et al. N Engl J Med. 2004 Feb 26;350(9):913-22. doi: 10.1056/NEJMra032207. N Engl J Med. 2004. PMID: 14985489 Review. No abstract available.

9

Gene therapy insertional mutagenesis insights.

Davé UP, Jenkins NA, Copeland NG. Davé UP, et al. Science. 2004 Jan 16;303(5656):333. doi: 10.1126/science.1091667. Science. 2004. PMID: 14726584 No abstract available.

10

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1.

Hacein-Bey-Abina S, Von Kalle C, Schmidt M, McCormack MP, Wulffraat N, Leboulch P, Lim A, Osborne CS, Pawliuk R, Morillon E, Sorensen R, Forster A, Fraser P, Cohen JI, de Saint Basile G, Alexander I, Wintergerst U, Frebourg T, Aurias A, Stoppa-Lyonnet D, Romana S, Radford-Weiss I, Gross F, Valensi F, Delabesse E, Macintyre E, Sigaux F, Soulier J, Leiva LE, Wissler M, Prinz C, Rabbitts TH, Le Deist F, Fischer A, Cavazzana-Calvo M. Hacein-Bey-Abina S, et al. Science. 2003 Oct 17;302(5644):415-9. doi: 10.1126/science.1088547. Science. 2003. PMID: 14564000

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