PubMed (OMIM) for id: 6678

Year	Number of Results
1981	1
1986	3
1988	3
1990	1
1992	1
1993	1
1994	1
1998	2
2003	2
2005	1
2006	1
2011	1
2015	1
2024	0

1

Recessive osteogenesis imperfecta caused by missense mutations in SPARC.

Mendoza-Londono R, Fahiminiya S, Majewski J; Care4Rare Canada Consortium; Tétreault M, Nadaf J, Kannu P, Sochett E, Howard A, Stimec J, Dupuis L, Roschger P, Klaushofer K, Palomo T, Ouellet J, Al-Jallad H, Mort JS, Moffatt P, Boudko S, Bächinger HP, Rauch F. Mendoza-Londono R, et al. Am J Hum Genet. 2015 Jun 4;96(6):979-85. doi: 10.1016/j.ajhg.2015.04.021. Epub 2015 May 28. Am J Hum Genet. 2015. PMID: 26027498 Free PMC article.

2

TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression.

Seux M, Peuget S, Montero MP, Siret C, Rigot V, Clerc P, Gigoux V, Pellegrino E, Pouyet L, N'Guessan P, Garcia S, Dufresne M, Iovanna JL, Carrier A, André F, Dusetti NJ. Seux M, et al. Oncogene. 2011 Jul 7;30(27):3049-61. doi: 10.1038/onc.2011.25. Epub 2011 Feb 21. Oncogene. 2011. PMID: 21339733

3

Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A.

Nozaki M, Sakurai E, Raisler BJ, Baffi JZ, Witta J, Ogura Y, Brekken RA, Sage EH, Ambati BK, Ambati J. Nozaki M, et al. J Clin Invest. 2006 Feb;116(2):422-9. doi: 10.1172/JCI26316. J Clin Invest. 2006. PMID: 16453023 Free PMC article.

4

Genes that mediate breast cancer metastasis to lung.

Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, Viale A, Olshen AB, Gerald WL, Massagué J. Minn AJ, et al. Nature. 2005 Jul 28;436(7050):518-24. doi: 10.1038/nature03799. Nature. 2005. PMID: 16049480 Free PMC article.

5

SPARC-null mice exhibit increased adiposity without significant differences in overall body weight.

Bradshaw AD, Graves DC, Motamed K, Sage EH. Bradshaw AD, et al. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6045-50. doi: 10.1073/pnas.1030790100. Epub 2003 Apr 29. Proc Natl Acad Sci U S A. 2003. PMID: 12721366 Free PMC article.

6

Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM.

Brekken RA, Puolakkainen P, Graves DC, Workman G, Lubkin SR, Sage EH. Brekken RA, et al. J Clin Invest. 2003 Feb;111(4):487-95. doi: 10.1172/JCI16804. J Clin Invest. 2003. PMID: 12588887 Free PMC article.

7

Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens.

Gilmour DT, Lyon GJ, Carlton MB, Sanes JR, Cunningham JM, Anderson JR, Hogan BL, Evans MJ, Colledge WH. Gilmour DT, et al. EMBO J. 1998 Apr 1;17(7):1860-70. doi: 10.1093/emboj/17.7.1860. EMBO J. 1998. PMID: 9524110 Free PMC article.

8

Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin.

Sasaki T, Hohenester E, Göhring W, Timpl R. Sasaki T, et al. EMBO J. 1998 Mar 16;17(6):1625-34. doi: 10.1093/emboj/17.6.1625. EMBO J. 1998. PMID: 9501084 Free PMC article.

9

Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases.

Le Beau MM, Espinosa R 3rd, Neuman WL, Stock W, Roulston D, Larson RA, Keinanen M, Westbrook CA. Le Beau MM, et al. Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5484-8. doi: 10.1073/pnas.90.12.5484. Proc Natl Acad Sci U S A. 1993. PMID: 8516290 Free PMC article.

10

SPARC (secreted protein acidic and rich in cysteine) regulates endothelial cell shape and barrier function.

Goldblum SE, Ding X, Funk SE, Sage EH. Goldblum SE, et al. Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3448-52. doi: 10.1073/pnas.91.8.3448. Proc Natl Acad Sci U S A. 1994. PMID: 8159767 Free PMC article.

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