PubMed (GeneRIF) for id: 107221

Year	Number of Results
2007	2
2008	2
2009	2
2010	2
2011	1
2012	1
2013	3
2014	7
2015	7
2016	9
2017	14
2018	5
2019	4
2020	7
2021	8
2022	8
2023	7
2024	2

1

Free fatty acid receptor 4 (FFA4) activation attenuates obese asthma by suppressing adiposity and resolving metaflammation.

Son SE, Koh JM, Im DS. Son SE, et al. Biomed Pharmacother. 2024 May;174:116509. doi: 10.1016/j.biopha.2024.116509. Epub 2024 Apr 3. Biomed Pharmacother. 2024. PMID: 38574615 Free article.

2

Microglial Ffar4 deficiency promotes cognitive impairment in the context of metabolic syndrome.

Wang W, Li J, Cui S, Li J, Ye X, Wang Z, Zhang T, Jiang X, Kong Y, Chen X, Chen YQ, Zhu S. Wang W, et al. Sci Adv. 2024 Feb 2;10(5):eadj7813. doi: 10.1126/sciadv.adj7813. Epub 2024 Feb 2. Sci Adv. 2024. PMID: 38306420 Free PMC article.

3

Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors.

Nakajima S, Demers G, Machuca-Parra AI, Pour ZD, Bairamian D, Bouyakdan K, Fisette A, Kabahizi A, Robb J, Rodaros D, Laurent C, Ferreira G, Arbour N, Alquier T, Fulton S. Nakajima S, et al. J Neuroinflammation. 2023 Dec 19;20(1):302. doi: 10.1186/s12974-023-02978-5. J Neuroinflammation. 2023. PMID: 38111048 Free PMC article.

4

Generating Bone Marrow Chimeric Mouse Using GPR120 Deficient Mouse for the Study of DHA Inhibitory Effect on Osteoclast Formation and Bone Resorption.

Ma J, Kitaura H, Ohori F, Noguchi T, Marahleh A, Kinjo R, Kanou K, Ren J, Miura M, Narita K, Mizoguchi I. Ma J, et al. Int J Mol Sci. 2023 Nov 30;24(23):17000. doi: 10.3390/ijms242317000. Int J Mol Sci. 2023. PMID: 38069322 Free PMC article.

5

Double knockout of FFAR4 and FGF21 aggravates metabolic disorders in mice.

Wei L, Ye X, Cui S, Li D, Zhu S. Wei L, et al. Int J Biol Macromol. 2023 Dec 31;253(Pt 1):126553. doi: 10.1016/j.ijbiomac.2023.126553. Epub 2023 Aug 30. Int J Biol Macromol. 2023. PMID: 37657572

6

FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic syndrome.

Zhang N, Harsch B, Zhang MJ, Gyberg DJ, Stevens JA, Wagner BM, Mendelson J, Patterson MT, Orchard DA, Healy CL, Williams JW, Townsend D, Shearer GC, Murphy KA, O'Connell TD. Zhang N, et al. J Lipid Res. 2023 Jun;64(6):100374. doi: 10.1016/j.jlr.2023.100374. Epub 2023 Apr 17. J Lipid Res. 2023. PMID: 37075982 Free PMC article.

7

GPR120 promotes neutrophil control of intestinal bacterial infection.

Zhou Z, Yang W, Yu T, Yu Y, Zhao X, Yu Y, Gu C, Bilotta AJ, Yao S, Zhao Q, Golovko G, Li M, Cong Y. Zhou Z, et al. Gut Microbes. 2023 Jan-Dec;15(1):2190311. doi: 10.1080/19490976.2023.2190311. Gut Microbes. 2023. PMID: 36927391 Free PMC article.

8

Endogenous n-3 PUFAs Improve Non-Alcoholic Fatty Liver Disease through FFAR4-Mediated Gut-Liver Crosstalk.

Jiang X, Yang Q, Qu H, Chen Y, Zhu S. Jiang X, et al. Nutrients. 2023 Jan 22;15(3):586. doi: 10.3390/nu15030586. Nutrients. 2023. PMID: 36771292 Free PMC article.

9

Docosahexaenoic acid inhibits TNF-α-induced osteoclast formation and orthodontic tooth movement through GPR120.

Ma J, Kitaura H, Ogawa S, Ohori F, Noguchi T, Marahleh A, Nara Y, Pramusita A, Kinjo R, Kanou K, Kishikawa A, Ichimura A, Mizoguchi I. Ma J, et al. Front Immunol. 2023 Jan 18;13:929690. doi: 10.3389/fimmu.2022.929690. eCollection 2022. Front Immunol. 2023. PMID: 36741381 Free PMC article.

10

FFAR4 improves the senescence of tubular epithelial cells by AMPK/SirT3 signaling in acute kidney injury.

Yang L, Wang B, Guo F, Huang R, Liang Y, Li L, Tao S, Yin T, Fu P, Ma L. Yang L, et al. Signal Transduct Target Ther. 2022 Nov 30;7(1):384. doi: 10.1038/s41392-022-01254-x. Signal Transduct Target Ther. 2022. PMID: 36450712 Free PMC article.

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