PubMed (GeneRIF) for id: 120892

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38512027,38368930,38307024,38287861,38266062,38227290,38135900,38092815,37904222,37889931,37874617,37837096,37788370,37759704,37708949,37698513,37674036,37633049,37625589,37584472,37482924,37473971,37371062,37269951,37238714,37218402,37207563,37201327,37189360,37133994,37116292,37086089,37066923,37046401,37021623,36972292,36803807,36780781,36764357,36716346,36690080,36671564,36654782,36596520,36510024,36358947,36219522,36011337,35995594,35965315,35963526,35950872,35934920,35929078,35805938,35781002,35708213,35654702,35608967,35421781,35326469,35266954,35217606,35192607,35152441,35147886,35077669,35049090,35029295,34991886,34929286,34914695,34859503,34686322,34668587,34626666,34590578,34551822,34542912,34495322,34425330,34382495,34328508,34272628,34196120,34145320,34125248,34114604,34107286,34088839,34060004,34043192,34008015,33998549,33960369,33938021,33918221,33915162,33894056,33881531,33876242,33784003,33781610,33769432,33765413,33640967,33561776,33527742,33506668,33498474,33494262,33483550,33466414,33459343,33454605,33434630,33433017,33422895,33388928,33158606,33152738,33142859,33122450,33107648,33057020,33018482,33015738,32999056,32975566,32972043,32931768,32926469,32916992,32879386,32875616,32873436,32846140,32814344,32794657,32783917,32722212,32719233,32709066,32677286,32652692,32643832,32631998,32486414,32461697,32422864,32398759,32375873,32375042,32374202,32359446,32353202,32318850,32310186,32180132,32123243,32073681,32065426,32057291,32007961,31980808,31958187,31813996,31813991,31804465,31733655,31698024,31680121,31663853,31640854,31631040,31626293,31624137,31621607,31605779,31552791,31505072,31493133,31489563,31487119,31428781,31348549,31308240,31292011,31261377,31180559,31046837,31038182,30982740,30945962,30927072,30844370,30837320,30799274,30796162,30720180,30709905,30670570,30640902,30635421,30629163,30597143,30573413,30562929,30536063,30507963,30485545,30481588,30398148,30333048,30291536,30288804,30269383,30145825,30121215,30091236,30089035,30067506,30055128,30049590,30039155,29989150,29917075,29903014,29894291,29884186,29812962,29789389,29760073,29743203,29735704,29705653,29665080,29627023,29576439,29568677,29567424,29550548,29549916,29537215,29513666,29482628,29472595,29456161,29456132,29402177,29369793,29369408,29357897,29321258,29309488,29268033,29253086,29249679,29248340,29246723,29241968,29223392,29177506,29166931,29131875,29129681,29127256,29127255,29125462,29088368,28991672,28973664,28973420,28941828,28888991,28826027,28723952,28710481,28697798,28686318,28679601,28657124,28647363,28582422,28487191,28483388,28453723,28445933,28406934,28352666,28321439,28320779,28235153,28205494,28202711,28202680,28202674,28202670,28202669,28202668,28202667,28202666,28202665,28202664,28158614,28131193,28102045,28099919,28071824,28028237,27975167,27913672,27913671,27913670,27913669,27913668,27890708,27884177,27863501,27839916,27832104,27830463,27814993,27812199,27812003,27798102,27794539,27777137,27751534,27717584,27709685,27699718,27692902,27653520,27640816,27631370,27628070,27613114,27521182,27503089,27449028,27430880,27423549,27399248,27384489,27314038,27260835,27220776,27133195,27111571,27093107,27091104,27063942,27041685,27023913,27004687,26985725,26965688,26947123,26930193,26917005,26894577,26865512,26844546,26824392,26747879,26744328,26687033,26686514,26675812,26651604,26600626,26536050,26519280,26468079,26435084,26403521,26384650,26375402,26366513,26365310,26355680,26346174,26311745,26310572,26306001,26268663,26268594,26234753,26213354,26177462,26159606,26123485,26062626,26056228,26014385,26011561,26009181,25962553,25952961,25939886,25926623,25899316,25888648,25842821,25840672,25830304,25821816,25809001,25804954,25786808,25761573,25731749,25703537,25650144,25648416,25605758,25521227,25511328,25500533,25487881,25446991,25434972,25427558,25416817,25401981,25401511,25394383,25378673,25360523,25353650,25316291,25301747,25243190,25228699,25201882,25174890,25127457,25107341,25080504,25062988,25048644,25027012,25017139,25008396,25000966,24997548,24973808,24957201,24947832,24942733,24916379,24903616,24863511,24849765,24836358,24830390,24816003,24794857,24788225,24777780,24758914,24754922,24729340,24725412,24695735,24687852,24652679,24633735,24631561,24591621,24576675,24559644,24482120,24470158,24403142,24398085,24375786,24360742,24357540,24351927,24339985,24326068,24275654,24262189,24251413,24243757,24211199,24167564,24148854,24123150,24095219,24080176,24046064,24040382,24018986,24015287,24014121,23967090,23963289,23938341,23937295,23937259,23932063,23924436,23916833,23913756,23895867,23886663,23842774,23824357,23820587,23771111,23764467,23726462,23664753,23628791,23624603,23588498,23531835,23507417,23472874,23455607,23421816,23389884,23379419,23357204,23325906,23318930,23300640,23268655,23250886,23241745,23241358,23227859,23220480,23183827,23182315,23125283,23115130,23082216,23075850,23074843,23055502,22998870,22988882,22988880,22988879,22988878,22988877,22988875,22988874,22988873,22988872,22988870,22988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Results by year

Year	Number of Results
2002	1
2003	1
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2005	33
2006	50
2007	65
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2012	91
2013	60
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1,006 results

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RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors.

Dou D, Aiken J, Holzbaur ELF. Dou D, et al. J Cell Biol. 2024 Jun 3;223(6):e202307092. doi: 10.1083/jcb.202307092. Epub 2024 Mar 21. J Cell Biol. 2024. PMID: 38512027 Free PMC article.

VPS35 and retromer dysfunction in Parkinson's disease.

Rowlands J, Moore DJ. Rowlands J, et al. Philos Trans R Soc Lond B Biol Sci. 2024 Apr 8;379(1899):20220384. doi: 10.1098/rstb.2022.0384. Epub 2024 Feb 19. Philos Trans R Soc Lond B Biol Sci. 2024. PMID: 38368930 Free PMC article. Review.

The LRRK2 kinase substrates RAB8a and RAB10 contribute complementary but distinct disease-relevant phenotypes in human neurons.

Mamais A, Sanyal A, Fajfer A, Zykoski CG, Guldin M, Riley-DiPaolo A, Subrahmanian N, Gibbs W, Lin S, LaVoie MJ. Mamais A, et al. Stem Cell Reports. 2024 Feb 13;19(2):163-173. doi: 10.1016/j.stemcr.2024.01.001. Epub 2024 Feb 1. Stem Cell Reports. 2024. PMID: 38307024 Free PMC article.

The Effect of p.G2019S Mutation in the LRRK2 Gene on the Activity of Lysosomal Hydrolases and the Clinical Features of Parkinson's Disease Associated with p.N370S Mutation in the GBA1 Gene.

Usenko TS, Timofeeva A, Beletskaia M, Basharova K, Baydakova G, Bezrukova A, Grunina M, Emelyanov A, Miliukhina I, Zakharova E, Pchelina S. Usenko TS, et al. J Integr Neurosci. 2024 Jan 16;23(1):16. doi: 10.31083/j.jin2301016. J Integr Neurosci. 2024. PMID: 38287861 Free article.

Comprehensive analysis of clinical and biological features in Parkinson's disease associated with the LRRK2 G2019S mutation: Data from the PPMI study.

Sun X, Dou K, Xue L, Xie Y, Yang Y, Xie A. Sun X, et al. Clin Transl Sci. 2024 Jan;17(1):e13720. doi: 10.1111/cts.13720. Clin Transl Sci. 2024. PMID: 38266062 Free PMC article.

The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response.

Eguchi T, Sakurai M, Wang Y, Saito C, Yoshii G, Wileman T, Mizushima N, Kuwahara T, Iwatsubo T. Eguchi T, et al. J Cell Biol. 2024 Mar 4;223(3):e202302067. doi: 10.1083/jcb.202302067. Epub 2024 Jan 16. J Cell Biol. 2024. PMID: 38227290 Free PMC article.

Targeting Rab-RILPL interactions as a strategy to downregulate pathogenic LRRK2 in Parkinson's disease.

Alexander KK, Naaldijk Y, Fasiczka R, Brahmia B, Chen T, Hilfiker S, Kennedy EJ. Alexander KK, et al. J Pept Sci. 2024 May;30(5):e3563. doi: 10.1002/psc.3563. Epub 2023 Dec 22. J Pept Sci. 2024. PMID: 38135900

Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function.

Ohtonen S, Giudice L, Jäntti H, Fazaludeen MF, Shakirzyanova A, Gómez-Budia M, Välimäki NN, Niskanen J, Korvenlaita N, Fagerlund I, Koistinaho J, Amiry-Moghaddam M, Savchenko E, Roybon L, Lehtonen Š, Korhonen P, Malm T. Ohtonen S, et al. Sci Rep. 2023 Dec 13;13(1):22118. doi: 10.1038/s41598-023-49294-9. Sci Rep. 2023. PMID: 38092815 Free PMC article.

LRRK2 is involved in the chemotaxis of neutrophils and differentiated HL-60 cells, and the inhibition of LRRK2 kinase activity increases fMLP-induced chemotactic activity.

Mazaki Y, Handa H, Fumoto Y, Horinouchi T, Onodera Y. Mazaki Y, et al. Cell Commun Signal. 2023 Oct 30;21(1):300. doi: 10.1186/s12964-023-01305-y. Cell Commun Signal. 2023. PMID: 37904222 Free PMC article.

Localization of PPM1H phosphatase tunes Parkinson's disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis.

Yeshaw WM, Adhikari A, Chiang CY, Dhekne HS, Wawro PS, Pfeffer SR. Yeshaw WM, et al. Proc Natl Acad Sci U S A. 2023 Oct 31;120(44):e2315171120. doi: 10.1073/pnas.2315171120. Epub 2023 Oct 27. Proc Natl Acad Sci U S A. 2023. PMID: 37889931 Free PMC article.

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