PubMed (GeneRIF) for id: 19152

Year	Number of Results
2004	1
2007	1
2008	1
2009	1
2012	2
2014	3
2015	1
2016	1
2020	2
2023	1
2024	0

1

N-glycan in the variable region of monoclonal ACPA (CCP-Ab1) promotes the exacerbation of experimental arthritis.

Kawataka M, Ouhara K, Kobayashi E, Shinoda K, Tobe K, Fujimori R, Mizuno N, Sugiyama E, Ozawa T, Kishi H. Kawataka M, et al. Rheumatology (Oxford). 2023 Dec 1;62(12):3968-3977. doi: 10.1093/rheumatology/kead130. Rheumatology (Oxford). 2023. PMID: 36944270

2

Lack of Proteinase 3 Stabilizes Advanced Atherosclerotic Lesions.

Ortega-Gomez A, Soehnlein O. Ortega-Gomez A, et al. Thromb Haemost. 2020 Jun;120(6):994-997. doi: 10.1055/s-0040-1710316. Epub 2020 May 13. Thromb Haemost. 2020. PMID: 32403136 No abstract available.

3

Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD.

Mirea AM, Stienstra R, Kanneganti TD, Tack CJ, Chavakis T, Toonen EJM, Joosten LAB. Mirea AM, et al. Inflammation. 2020 Jun;43(3):1054-1064. doi: 10.1007/s10753-020-01190-4. Inflammation. 2020. PMID: 32002713 Free PMC article.

4

Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance.

Toonen EJ, Mirea AM, Tack CJ, Stienstra R, Ballak DB, van Diepen JA, Hijmans A, Chavakis T, Dokter WH, Pham CT, Netea MG, Dinarello CA, Joosten LA. Toonen EJ, et al. Mol Med. 2016 May 24;22:202-14. doi: 10.2119/molmed.2016.00033. Mol Med. 2016. PMID: 27261776 Free PMC article.

5

Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis.

Millet A, Martin KR, Bonnefoy F, Saas P, Mocek J, Alkan M, Terrier B, Kerstein A, Tamassia N, Satyanarayanan SK, Ariel A, Ribeil JA, Guillevin L, Cassatella MA, Mueller A, Thieblemont N, Lamprecht P, Mouthon L, Perruche S, Witko-Sarsat V. Millet A, et al. J Clin Invest. 2015 Nov 2;125(11):4107-21. doi: 10.1172/JCI78182. Epub 2015 Oct 5. J Clin Invest. 2015. PMID: 26436651 Free PMC article.

6

PR3-ANCA: a promising biomarker in primary sclerosing cholangitis (PSC).

Stinton LM, Bentow C, Mahler M, Norman GL, Eksteen B, Mason AL, Kaplan GG, Lindkvist B, Hirschfield GM, Milkiewicz P, Cheung A, Janssen HL, Fritzler MJ. Stinton LM, et al. PLoS One. 2014 Nov 14;9(11):e112877. doi: 10.1371/journal.pone.0112877. eCollection 2014. PLoS One. 2014. PMID: 25397578 Free PMC article.

7

Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation.

Loison F, Zhu H, Karatepe K, Kasorn A, Liu P, Ye K, Zhou J, Cao S, Gong H, Jenne DE, Remold-O'Donnell E, Xu Y, Luo HR. Loison F, et al. J Clin Invest. 2014 Oct;124(10):4445-58. doi: 10.1172/JCI76246. Epub 2014 Sep 2. J Clin Invest. 2014. PMID: 25180606 Free PMC article.

8

Increased neutrophil elastase and proteinase 3 and augmented NETosis are closely associated with β-cell autoimmunity in patients with type 1 diabetes.

Wang Y, Xiao Y, Zhong L, Ye D, Zhang J, Tu Y, Bornstein SR, Zhou Z, Lam KS, Xu A. Wang Y, et al. Diabetes. 2014 Dec;63(12):4239-48. doi: 10.2337/db14-0480. Epub 2014 Aug 4. Diabetes. 2014. PMID: 25092677

9

Proteinase 3, the autoantigen in granulomatosis with polyangiitis, associates with calreticulin on apoptotic neutrophils, impairs macrophage phagocytosis, and promotes inflammation.

Gabillet J, Millet A, Pederzoli-Ribeil M, Tacnet-Delorme P, Guillevin L, Mouthon L, Frachet P, Witko-Sarsat V. Gabillet J, et al. J Immunol. 2012 Sep 1;189(5):2574-83. doi: 10.4049/jimmunol.1200600. Epub 2012 Jul 27. J Immunol. 2012. PMID: 22844112

10

Contradictory functions (activation/termination) of neutrophil proteinase 3 enzyme (PR3) in interleukin-33 biological activity.

Bae S, Kang T, Hong J, Lee S, Choi J, Jhun H, Kwak A, Hong K, Kim E, Jo S, Kim S. Bae S, et al. J Biol Chem. 2012 Mar 9;287(11):8205-13. doi: 10.1074/jbc.M111.295055. Epub 2012 Jan 23. J Biol Chem. 2012. PMID: 22270365 Free PMC article.

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