PubMed (GeneRIF) for id: 20787

Year	Number of Results
2001	1
2002	8
2003	8
2004	12
2005	11
2006	6
2007	16
2008	17
2009	22
2010	16
2011	15
2012	13
2013	15
2014	12
2015	11
2016	21
2017	18
2018	19
2019	8
2020	6
2021	10
2022	4
2023	4
2024	3

1

DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER.

Rong S, Xia M, Vale G, Wang S, Kim CW, Li S, McDonald JG, Radhakrishnan A, Horton JD. Rong S, et al. Cell Metab. 2024 Mar 5;36(3):617-629.e7. doi: 10.1016/j.cmet.2024.01.011. Epub 2024 Feb 9. Cell Metab. 2024. PMID: 38340721 Free PMC article.

2

Macrophage SREBP1 regulates skeletal muscle regeneration.

Oishi Y, Koike H, Kumagami N, Nakagawa Y, Araki M, Taketomi Y, Miki Y, Matsuda S, Matsuzaka T, Ozawa H, Shimano H, Murakami M, Manabe I. Oishi Y, et al. Front Immunol. 2024 Jan 8;14:1251784. doi: 10.3389/fimmu.2023.1251784. eCollection 2023. Front Immunol. 2024. PMID: 38259495 Free PMC article.

3

The role of KLF2 in regulating hepatic lipogenesis and blood cholesterol homeostasis via the SCAP/SREBP pathway.

Huang Y, Wang YF, Ruan XZ, Lau CW, Wang L, Huang Y. Huang Y, et al. J Lipid Res. 2024 Jan;65(1):100472. doi: 10.1016/j.jlr.2023.100472. Epub 2023 Nov 9. J Lipid Res. 2024. PMID: 37949368 Free PMC article.

4

Exogenous H₂ S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.

Zhang S, Wang M, Li H, Li Q, Liu N, Dong S, Zhao Y, Pang K, Huang J, Ren C, Wang Y, Tian Z, Lu F, Zhang W. Zhang S, et al. J Cachexia Sarcopenia Muscle. 2023 Dec;14(6):2719-2732. doi: 10.1002/jcsm.13347. Epub 2023 Oct 30. J Cachexia Sarcopenia Muscle. 2023. PMID: 37899701 Free PMC article.

5

Caspase-11 contributes to site-1 protease cleavage and SREBP1 activation in the inflammatory response of macrophages.

Cheng Y, Manabe I, Hayakawa S, Endo Y, Oishi Y. Cheng Y, et al. Front Immunol. 2023 Jan 27;14:1009973. doi: 10.3389/fimmu.2023.1009973. eCollection 2023. Front Immunol. 2023. PMID: 36776855 Free PMC article.

6

Hepatocyte- or macrophage-specific SREBP-1a deficiency in mice exacerbates methionine- and choline-deficient diet-induced nonalcoholic fatty liver disease.

Araki M, Nakagawa Y, Saito H, Yamada Y, Han SI, Mizunoe Y, Ohno H, Miyamoto T, Sekiya M, Matsuzaka T, Sone H, Shimano H. Araki M, et al. Am J Physiol Gastrointest Liver Physiol. 2022 Dec 1;323(6):G627-G639. doi: 10.1152/ajpgi.00090.2022. Epub 2022 Oct 25. Am J Physiol Gastrointest Liver Physiol. 2022. PMID: 36283088 Free article.

7

Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.

Yenilmez B, Kelly M, Zhang GF, Wetoska N, Ilkayeva OR, Min K, Rowland L, DiMarzio C, He W, Raymond N, Lifshitz L, Pan M, Han X, Xie J, Friedline RH, Kim JK, Gao G, Herman MA, Newgard CB, Czech MP. Yenilmez B, et al. J Biol Chem. 2022 Oct;298(10):102401. doi: 10.1016/j.jbc.2022.102401. Epub 2022 Aug 18. J Biol Chem. 2022. PMID: 35988648 Free PMC article.

8

Srebf1c preserves hematopoietic stem cell function and survival as a switch of mitochondrial metabolism.

Lu Y, Zhang Z, Wang S, Qi Y, Chen F, Xu Y, Shen M, Chen M, Chen N, Yang L, Chen S, Wang F, Su Y, Hu M, Wang J. Lu Y, et al. Stem Cell Reports. 2022 Mar 8;17(3):599-615. doi: 10.1016/j.stemcr.2022.01.011. Epub 2022 Feb 10. Stem Cell Reports. 2022. PMID: 35148846 Free PMC article.

9

Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK-SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue.

Hinds TD Jr, Kipp ZA, Xu M, Yiannikouris FB, Morris AJ, Stec DF, Wahli W, Stec DE. Hinds TD Jr, et al. Cells. 2021 Dec 21;11(1):4. doi: 10.3390/cells11010004. Cells. 2021. PMID: 35011564 Free PMC article.

10

CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.

Zeng H, Qin H, Liao M, Zheng E, Luo X, Xiao A, Li Y, Chen L, Wei L, Zhao L, Ruan XZ, Yang P, Chen Y. Zeng H, et al. Mol Metab. 2022 Mar;57:101428. doi: 10.1016/j.molmet.2021.101428. Epub 2021 Dec 30. Mol Metab. 2022. PMID: 34974159 Free PMC article.

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