PubMed (GeneRIF) for id: 208449

Year	Number of Results
2010	2
2011	3
2012	4
2013	1
2014	1
2015	2
2016	3
2018	2
2019	3
2021	4
2024	0

1

Sphingomyelin synthases 1 and 2 exhibit phosphatidylcholine phospholipase C activity.

Chiang YP, Li Z, Chen Y, Cao Y, Jiang XC. Chiang YP, et al. J Biol Chem. 2021 Dec;297(6):101398. doi: 10.1016/j.jbc.2021.101398. Epub 2021 Nov 10. J Biol Chem. 2021. PMID: 34774525 Free PMC article.

2

A novel mechanism of thrombocytopenia by PS exposure through TMEM16F in sphingomyelin synthase 1 deficiency.

Fujii Y, Taniguchi M, Nagaya S, Ueda Y, Hashizume C, Watanabe K, Takeya H, Kosaka T, Okazaki T. Fujii Y, et al. Blood Adv. 2021 Oct 26;5(20):4265-4277. doi: 10.1182/bloodadvances.2020002922. Blood Adv. 2021. PMID: 34478523 Free PMC article.

3

Effect of liver total sphingomyelin synthase deficiency on plasma lipid metabolism.

Li Z, Chiang YP, He M, Zhang K, Zheng J, Wu W, Cai J, Chen Y, Chen G, Chen Y, Dong J, Worgall TS, Jiang XC. Li Z, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 May;1866(5):158898. doi: 10.1016/j.bbalip.2021.158898. Epub 2021 Feb 2. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33545384 Free PMC article.

4

Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry.

Niekamp P, Guzman G, Leier HC, Rashidfarrokhi A, Richina V, Pott F, Barisch C, Holthuis JCM, Tafesse FG. Niekamp P, et al. mBio. 2021 Jan 26;12(1):e03141-20. doi: 10.1128/mBio.03141-20. mBio. 2021. PMID: 33500344 Free PMC article.

5

Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation.

Matsumoto G, Hashizume C, Watanabe K, Taniguchi M, Okazaki T. Matsumoto G, et al. Mol Med. 2019 Dec 17;25(1):56. doi: 10.1186/s10020-019-0123-0. Mol Med. 2019. PMID: 31847800 Free PMC article.

6

Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response.

Wang C, Ming B, Wu X, Wu T, Cai S, Hu P, Tang J, Tan Z, Liu C, Zhong J, Zheng F, Dong L. Wang C, et al. EBioMedicine. 2019 Jul;45:578-587. doi: 10.1016/j.ebiom.2019.06.038. Epub 2019 Jun 28. EBioMedicine. 2019. PMID: 31262710 Free PMC article.

7

2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity.

Lou B, Liu Q, Hou J, Kabir I, Liu P, Ding T, Dong J, Mo M, Ye D, Chen Y, Bui HH, Roth K, Cao Y, Jiang XC. Lou B, et al. J Biol Chem. 2018 Nov 23;293(47):18328-18336. doi: 10.1074/jbc.RA118.005904. Epub 2018 Oct 10. J Biol Chem. 2018. PMID: 30305392 Free PMC article.

8

Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1.

Lu MH, Ji WL, Xu DE, Yao PP, Zhao XY, Wang ZT, Fang LP, Huang R, Lan LJ, Chen JB, Wang TH, Cheng LH, Xu RX, Liu CF, Puglielli L, Ma QH. Lu MH, et al. Exp Neurol. 2019 Jan;311:67-79. doi: 10.1016/j.expneurol.2018.09.012. Epub 2018 Sep 20. Exp Neurol. 2019. PMID: 30243987

9

Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus.

Taniguchi M, Tasaki T, Ninomiya H, Ueda Y, Kuremoto KI, Mitsutake S, Igarashi Y, Okazaki T, Takegami T. Taniguchi M, et al. Sci Rep. 2016 Nov 28;6:37829. doi: 10.1038/srep37829. Sci Rep. 2016. PMID: 27892528 Free PMC article.

10

Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice.

Wittmann A, Grimm MO, Scherthan H, Horsch M, Beckers J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Ford SJ, Burton NC, Razansky D, Trümbach D, Aichler M, Walch AK, Calzada-Wack J, Neff F, Wurst W, Hartmann T, Floss T. Wittmann A, et al. PLoS One. 2016 Oct 27;11(10):e0164298. doi: 10.1371/journal.pone.0164298. eCollection 2016. PLoS One. 2016. PMID: 27788151 Free PMC article.

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