Abstract
MS4A4A regulates the expression of arginase 1 in macrophages under IL4 stimulation. Also, MS4A4A regulates eosinophil infiltration during lung allergic inflammation induced by intranasal administration of house dust mite.
Keywords:
IL4; MS4A4A; allergic immunity; arginase 1; macrophage.
© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antigens, Dermatophagoides / immunology
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Arginase / genetics
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Arginase / metabolism*
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Cell Differentiation
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Eosinophils / immunology*
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Hypersensitivity / immunology*
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Lung / immunology*
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Macrophage Activation
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Macrophages / physiology*
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Membrane Proteins / genetics
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Membrane Proteins / metabolism*
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Mice
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Mice, Knockout
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Pneumonia / immunology*
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Pyroglyphidae
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Up-Regulation
Substances
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Antigens, Dermatophagoides
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Membrane Proteins
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Ms4a4b protein, mouse
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Arg1 protein, mouse
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Arginase