PubMed (GeneRIF) for id: 675

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Results by year

Year	Number of Results
2000	7
2001	31
2002	78
2003	71
2004	73
2005	54
2006	75
2007	115
2008	141
2009	157
2010	168
2011	113
2012	117
2013	106
2014	105
2015	113
2016	131
2017	114
2018	89
2019	80
2020	114
2021	108
2022	81
2023	46
2024	13

1,980 results

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Page 1

Functional analysis and clinical classification of 462 germline BRCA2 missense variants affecting the DNA binding domain.

Hu C, Huang H, Na J, Lumby C, Abozaid M, Holdren MA, Rao TJ, Karam R, Pesaran T, Weyandt JD, Csuy CM, Seelaus CA, Young CC, Fulk K, Heidari Z, Morais Lyra PC Jr, Couch RE, Persons B, Polley EC, Gnanaolivu RD, Boddicker NJ, Monteiro ANA, Yadav S, Domchek SM, Richardson ME, Couch FJ. Hu C, et al. Am J Hum Genet. 2024 Mar 7;111(3):584-593. doi: 10.1016/j.ajhg.2024.02.002. Epub 2024 Feb 27. Am J Hum Genet. 2024. PMID: 38417439

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health.

De Matteis E, Tumolo MR, Tarantino P, Ciccarese M, Grassi T, Bagordo F, De Giorgio MR, Rizzo E, Ronzino G. De Matteis E, et al. Oncotarget. 2024 Feb 22;15:134-141. doi: 10.18632/oncotarget.28561. Oncotarget. 2024. PMID: 38386807 Free PMC article.

Central nervous system metastases in breast cancer patients with germline BRCA pathogenic variants compared to non-carriers: a matched-pair analysis.

Ben-Zion Berliner M, Yust-Katz S, Lavie I, Goldberg Y, Kedar I, Yerushalmi R. Ben-Zion Berliner M, et al. BMC Cancer. 2024 Feb 16;24(1):219. doi: 10.1186/s12885-024-11975-7. BMC Cancer. 2024. PMID: 38365640 Free PMC article.

BRCA1, BRCA2, and TP53 germline and somatic variants and clinicopathological characteristics of Brazilian patients with epithelial ovarian cancer.

Richau CS, Scherer NM, Matta BP, de Armas EM, de Barros Moreira FC, Bergmann A, Pereira Chaves CB, Boroni M, Dos Santos ACE, Moreira MAM. Richau CS, et al. Cancer Med. 2024 Feb;13(3):e6729. doi: 10.1002/cam4.6729. Epub 2024 Feb 2. Cancer Med. 2024. PMID: 38308422 Free PMC article.

Reclassifying BRCA1 c.4358-2A > G and BRCA2 c.475 + 5G > C variants from "Uncertain Significance" to "Pathogenic" based on minigene assays and clinical evidence.

Ning Y, Zhang Y, Tian T, Chen Y, Wang J, Lei K, Cui Z. Ning Y, et al. J Cancer Res Clin Oncol. 2024 Feb 1;150(2):62. doi: 10.1007/s00432-023-05597-y. J Cancer Res Clin Oncol. 2024. PMID: 38300310 Free PMC article.

Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer.

Harvey-Jones E, Raghunandan M, Robbez-Masson L, Magraner-Pardo L, Alaguthurai T, Yablonovitch A, Yen J, Xiao H, Brough R, Frankum J, Song F, Yeung J, Savy T, Gulati A, Alexander J, Kemp H, Starling C, Konde A, Marlow R, Cheang M, Proszek P, Hubank M, Cai M, Trendell J, Lu R, Liccardo R, Ravindran N, Llop-Guevara A, Rodriguez O, Balmana J, Lukashchuk N, Dorschner M, Drusbosky L, Roxanis I, Serra V, Haider S, Pettitt SJ, Lord CJ, Tutt ANJ. Harvey-Jones E, et al. Ann Oncol. 2024 Apr;35(4):364-380. doi: 10.1016/j.annonc.2024.01.003. Epub 2024 Jan 19. Ann Oncol. 2024. PMID: 38244928 Free article.

BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair.

Lim PX, Zaman M, Feng W, Jasin M. Lim PX, et al. Mol Cell. 2024 Feb 1;84(3):447-462.e10. doi: 10.1016/j.molcel.2023.12.025. Epub 2024 Jan 19. Mol Cell. 2024. PMID: 38244544

BRCA1 and BRCA2 germline mutations in Chinese Hakka breast cancer patients.

Zhang Y, Wu H, Gan C, Rao H, Wang Q, Guo X. Zhang Y, et al. BMC Med Genomics. 2024 Jan 2;17(1):3. doi: 10.1186/s12920-023-01772-9. BMC Med Genomics. 2024. PMID: 38167124 Free PMC article.

[BRCA2 Mutation Profile in a Proband with Hereditary Breast and Ovarian Cancer-Two Germline Pathogenic Variants Aligned in the Cis Position].

Yukisawa S, Kakinuma T, Yotsumoto J, Kawakami K, Furukawa J, Shinozaki H. Yukisawa S, et al. Gan To Kagaku Ryoho. 2023 Oct;50(10):1089-1091. Gan To Kagaku Ryoho. 2023. PMID: 38035841 Japanese.

Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis.

Metcalfe K, Huzarski T, Gronwald J, Kotsopoulos J, Kim R, Moller P, Pal T, Aeilts A, Eisen A, Karlan B, Bordeleau L, Tung N, Olopade O, Zakalik D, Singer CF, Foulkes W, Couch F, Neuhausen SL, Eng C, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Metcalfe K, et al. Br J Cancer. 2024 Feb;130(2):269-274. doi: 10.1038/s41416-023-02503-8. Epub 2023 Nov 29. Br J Cancer. 2024. PMID: 38030749

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