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The effect of genetic polymorphisms of RARA gene on the adverse effects profile of isotretinoin-treated acne patients.

Alzoubi KH, Khabour OF, Hassan RE, Qarqaz F, Al-Azzam S, Mhaidat N.

Int J Clin Pharmacol Ther. 2013 Aug;51(8):631-40. doi: 10.5414/CP201874.


Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies.

Ablain J, Leiva M, Peres L, Fonsart J, Anthony E, de Thé H.

J Exp Med. 2013 Apr 8;210(4):647-53. doi: 10.1084/jem.20122337. Epub 2013 Mar 18.


Practical synthesis of a chromene analog for use as a retinoic acid receptor alpha antagonist lead compound.

Jetson R, Malik N, Luniwal A, Chari V, Ratnam M, Erhardt P.

Eur J Med Chem. 2013 May;63:104-8. doi: 10.1016/j.ejmech.2013.02.012. Epub 2013 Feb 19.


Retinoic acid receptor-dependent, cell-autonomous, endogenous retinoic acid signaling and its target genes in mouse collecting duct cells.

Wong YF, Wilson PD, Unwin RJ, Norman JT, Arno M, Hendry BM, Xu Q.

PLoS One. 2012;7(9):e45725. doi: 10.1371/journal.pone.0045725. Epub 2012 Sep 26.


Conditional RARα knockout mice reveal acute requirement for retinoic acid and RARα in homeostatic plasticity.

Sarti F, Schroeder J, Aoto J, Chen L.

Front Mol Neurosci. 2012 Feb 15;5:16. doi: 10.3389/fnmol.2012.00016. eCollection 2012.


Infantile acute promyelocytic leukemia without an RARα rearrangement.

Hori T, Suzuki N, Hatakeyama N, Yamamoto M, Inazawa N, Miyachi H, Taki T, Tsutsumi H.

Pediatr Int. 2011 Dec;53(6):1070-3. doi: 10.1111/j.1442-200X.2011.03364.x. No abstract available.


Retinoid-regulated FGF8f secretion by osteoblasts bypasses retinoid stimuli to mediate granulocytic differentiation of myeloid leukemia cells.

Chaudhry P, Yang X, Wagner M, Jong A, Wu L.

Mol Cancer Ther. 2012 Feb;11(2):267-76. doi: 10.1158/1535-7163.MCT-11-0584. Epub 2011 Dec 1.


Novel retinoic acid receptor alpha agonists for treatment of kidney disease.

Zhong Y, Wu Y, Liu R, Li Z, Chen Y, Evans T, Chuang P, Das B, He JC.

PLoS One. 2011;6(11):e27945. doi: 10.1371/journal.pone.0027945. Epub 2011 Nov 18.


Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility.

Brazda P, Szekeres T, Bravics B, Tóth K, Vámosi G, Nagy L.

J Cell Sci. 2011 Nov 1;124(Pt 21):3631-42. doi: 10.1242/jcs.086082. Epub 2011 Nov 1.


Melatonin synthesized by T lymphocytes as a ligand of the retinoic acid-related orphan receptor.

Lardone PJ, Guerrero JM, Fernández-Santos JM, Rubio A, Martín-Lacave I, Carrillo-Vico A.

J Pineal Res. 2011 Nov;51(4):454-62. doi: 10.1111/j.1600-079X.2011.00909.x. Epub 2011 Jul 7.


Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha.

Hall JA, Cannons JL, Grainger JR, Dos Santos LM, Hand TW, Naik S, Wohlfert EA, Chou DB, Oldenhove G, Robinson M, Grigg ME, Kastenmayer R, Schwartzberg PL, Belkaid Y.

Immunity. 2011 Mar 25;34(3):435-47. doi: 10.1016/j.immuni.2011.03.003.


c-Jun N-terminal kinase activation by oxidative stress suppresses retinoid signaling through proteasomal degradation of retinoic acid receptor α protein in hepatic cells.

Hoshikawa Y, Kanki K, Ashla AA, Arakaki Y, Azumi J, Yasui T, Tezuka Y, Matsumi Y, Tsuchiya H, Kurimasa A, Hisatome I, Hirano T, Fujimoto J, Kagechika H, Shomori K, Ito H, Shiota G.

Cancer Sci. 2011 May;102(5):934-41. doi: 10.1111/j.1349-7006.2011.01889.x. Epub 2011 Feb 24.


RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis.

Cohn E, Ossowski L, Bertran S, Marzan C, Farias EF.

Breast Cancer Res. 2010;12(5):R79. doi: 10.1186/bcr2724. Epub 2010 Oct 5.


Amplification of the RARA gene in acute myeloid leukemia: significant finding or coincidental observation?

Asleson AD, Morgan V, Smith S, Velagaleti GV.

Cancer Genet Cytogenet. 2010 Oct 1;202(1):33-7. doi: 10.1016/j.cancergencyto.2010.06.003.


A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor.

le Maire A, Teyssier C, Erb C, Grimaldi M, Alvarez S, de Lera AR, Balaguer P, Gronemeyer H, Royer CA, Germain P, Bourguet W.

Nat Struct Mol Biol. 2010 Jul;17(7):801-7. doi: 10.1038/nsmb.1855. Epub 2010 Jun 13.


Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580.

Lu Y, Bertran S, Samuels TA, Mira-y-Lopez R, Farias EF.

Oncogene. 2010 Jun 24;29(25):3665-76. doi: 10.1038/onc.2010.119. Epub 2010 May 10.


Role of retinoic acid-related orphan receptor-alpha in differentiation of human mesenchymal stem cells along with osteoblastic lineage.

Miyamoto S, Cooper L, Watanabe K, Yamamoto S, Inoue H, Mishima K, Saito I.

Pathobiology. 2010;77(1):28-37. doi: 10.1159/000272952. Epub 2010 Feb 25.


Aberrant distribution of junctional complex components in retinoic acid receptor alpha-deficient mice.

Chung SS, Choi C, Wang X, Hallock L, Wolgemuth DJ.

Microsc Res Tech. 2010 Jun;73(6):583-96. doi: 10.1002/jemt.20797.


The retinoic acid receptor alpha (RARA) gene is not associated with myopia, hypermetropia, and ocular biometric measures.

Veerappan S, Schäche M, Pertile KK, Islam FM, Chen CY, Mitchell P, Dirani M, Baird PN.

Mol Vis. 2009 Jul 17;15:1390-7.


The involvement of retinoic acid receptor-alpha in corticotropin-releasing hormone gene expression and affective disorders.

Chen XN, Meng QY, Bao AM, Swaab DF, Wang GH, Zhou JN.

Biol Psychiatry. 2009 Nov 1;66(9):832-9. doi: 10.1016/j.biopsych.2009.05.031. Epub 2009 Jul 12.


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