PubMed for id: 3812

Year	Number of Results
1991	2
1992	1
1993	5
1994	1
1995	1
1996	2
1997	4
1998	3
1999	2
2000	3
2001	1
2002	4
2003	6
2004	7
2005	7
2006	8
2007	8
2008	14
2009	12
2010	14
2011	12
2012	13
2013	15
2014	1
2024	0

1

Tpl2 knockout keratinocytes have increased biomarkers for invasion and metastasis.

Decicco-Skinner KL, Jung SA, Tabib T, Gwilliam JC, Alexander H, Goodheart SE, Merchant AS, Shan M, Garber C, Wiest JS. Decicco-Skinner KL, et al. Carcinogenesis. 2013 Dec;34(12):2789-98. doi: 10.1093/carcin/bgt319. Epub 2013 Sep 25. Carcinogenesis. 2013. PMID: 24067898 Free PMC article.

2

Tpl2 inhibitors thwart endothelial cell function in angiogenesis and peritoneal dissemination.

Lee WJ, Lan KH, Chou CT, Yi YC, Chen WC, Pan HC, Peng YC, Wang KB, Chen YC, Chao TH, Tien HR, Sheu WH, Sheu ML. Lee WJ, et al. Neoplasia. 2013 Sep;15(9):1036-48. doi: 10.1593/neo.121914. Neoplasia. 2013. PMID: 24027429 Free PMC article.

3

Honokiol thwarts gastric tumor growth and peritoneal dissemination by inhibiting Tpl2 in an orthotopic model.

Pan HC, Lai DW, Lan KH, Shen CC, Wu SM, Chiu CS, Wang KB, Sheu ML. Pan HC, et al. Carcinogenesis. 2013 Nov;34(11):2568-79. doi: 10.1093/carcin/bgt243. Epub 2013 Jul 4. Carcinogenesis. 2013. PMID: 23828905

4

Sterile inflammation in acetaminophen-induced liver injury is mediated by Cot/tpl2.

Sanz-Garcia C, Ferrer-Mayorga G, González-Rodríguez Á, Valverde AM, Martín-Duce A, Velasco-Martín JP, Regadera J, Fernández M, Alemany S. Sanz-Garcia C, et al. J Biol Chem. 2013 May 24;288(21):15342-51. doi: 10.1074/jbc.M112.439547. Epub 2013 Apr 9. J Biol Chem. 2013. PMID: 23572518 Free PMC article.

5

The protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs).

Martel G, Bérubé J, Rousseau S. Martel G, et al. PLoS One. 2013;8(3):e59116. doi: 10.1371/journal.pone.0059116. Epub 2013 Mar 19. PLoS One. 2013. PMID: 23527104 Free PMC article.

6

Altered prostanoid signaling contributes to increased skin tumorigenesis in Tpl2 knockout mice.

DeCicco-Skinner KL, Nolan SJ, Deshpande MM, Trovato EL, Dempsey TA, Wiest JS. DeCicco-Skinner KL, et al. PLoS One. 2013;8(2):e56212. doi: 10.1371/journal.pone.0056212. Epub 2013 Feb 15. PLoS One. 2013. PMID: 23457529 Free PMC article.

7

MAP3K8 kinase regulates myeloma growth by cell-autonomous and non-autonomous mechanisms involving myeloma-associated monocytes/macrophages.

Hebron E, Hope C, Kim J, Jensen JL, Flanagan C, Bhatia N, Maroulakou I, Mitsiades C, Miyamoto S, Callander N, Hematti P, Asimakopoulos F. Hebron E, et al. Br J Haematol. 2013 Mar;160(6):779-84. doi: 10.1111/bjh.12175. Epub 2012 Dec 18. Br J Haematol. 2013. PMID: 23252623 Free PMC article.

8

Interleukin-17 induces AP-1 activity and cellular transformation via upregulation of tumor progression locus 2 activity.

Kim G, Khanal P, Lim SC, Yun HJ, Ahn SG, Ki SH, Choi HS. Kim G, et al. Carcinogenesis. 2013 Feb;34(2):341-50. doi: 10.1093/carcin/bgs342. Epub 2012 Nov 3. Carcinogenesis. 2013. PMID: 23125217

9

Tumor progression locus 2 (Tpl2) deficiency does not protect against obesity-induced metabolic disease.

Lancaster GI, Kowalski GM, Estevez E, Kraakman MJ, Grigoriadis G, Febbraio MA, Gerondakis S, Banerjee A. Lancaster GI, et al. PLoS One. 2012;7(6):e39100. doi: 10.1371/journal.pone.0039100. Epub 2012 Jun 11. PLoS One. 2012. PMID: 22701749 Free PMC article.

10

Cot/tpl2-MKK1/2-Erk1/2 controls mTORC1-mediated mRNA translation in Toll-like receptor-activated macrophages.

López-Pelaéz M, Fumagalli S, Sanz C, Herrero C, Guerra S, Fernandez M, Alemany S. López-Pelaéz M, et al. Mol Biol Cell. 2012 Aug;23(15):2982-92. doi: 10.1091/mbc.E12-02-0135. Epub 2012 Jun 6. Mol Biol Cell. 2012. PMID: 22675026 Free PMC article.

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