PubMed for id: 227330583

Year	Number of Results
1997	1
1998	2
1999	2
2023	4
2024	1

1

Relationship of the bone phenotype of the Klotho mutant mouse model of accelerated aging to changes in skeletal architecture that occur with chronological aging.

Verlinden L, Li S, Veldurthy V, Carmeliet G, Christakos S. Verlinden L, et al. Front Endocrinol (Lausanne). 2024 Jan 30;15:1310466. doi: 10.3389/fendo.2024.1310466. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38352710 Free PMC article.

2

Histone deacetylase 9 exacerbates podocyte injury in hyperhomocysteinemia through epigenetic repression of Klotho.

Liu M, Zhang Y, Zhan P, Sun W, Dong C, Liu X, Yang Y, Wang X, Xie Y, Gao C, Hu H, Shi B, Wang Z, Guo C, Yi F. Liu M, et al. Pharmacol Res. 2023 Dec;198:107009. doi: 10.1016/j.phrs.2023.107009. Epub 2023 Nov 22. Pharmacol Res. 2023. PMID: 37995896 Free article.

3

Klotho inhibits renal ox-LDL deposition via IGF-1R/RAC1/OLR1 signaling to ameliorate podocyte injury in diabetic kidney disease.

Jiang W, Gan C, Zhou X, Yang Q, Chen D, Xiao H, Dai L, Chen Y, Wang M, Yang H, Li Q. Jiang W, et al. Cardiovasc Diabetol. 2023 Oct 27;22(1):293. doi: 10.1186/s12933-023-02025-w. Cardiovasc Diabetol. 2023. PMID: 37891556 Free PMC article.

4

Klotho regulates the myogenic response of muscle to mechanical loading and exercise.

Ochi E, Barrington A, Wehling-Henricks M, Avila M, Kuro-O M, Tidball JG. Ochi E, et al. Exp Physiol. 2023 Dec;108(12):1531-1547. doi: 10.1113/EP091263. Epub 2023 Oct 20. Exp Physiol. 2023. PMID: 37864311 Free PMC article.

5

Klotho increases antioxidant defenses in astrocytes and ubiquitin-proteasome activity in neurons.

Orellana AM, Mazucanti CH, Dos Anjos LP, de Sá Lima L, Kawamoto EM, Scavone C. Orellana AM, et al. Sci Rep. 2023 Sep 12;13(1):15080. doi: 10.1038/s41598-023-41166-6. Sci Rep. 2023. PMID: 37699938 Free PMC article.

6

Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia.

Kawaguchi H, Manabe N, Miyaura C, Chikuda H, Nakamura K, Kuro-o M. Kawaguchi H, et al. J Clin Invest. 1999 Aug;104(3):229-37. doi: 10.1172/JCI5705. J Clin Invest. 1999. PMID: 10430604 Free PMC article.

7

Molecular biology of aging.

Johnson FB, Sinclair DA, Guarente L. Johnson FB, et al. Cell. 1999 Jan 22;96(2):291-302. doi: 10.1016/s0092-8674(00)80567-x. Cell. 1999. PMID: 9988222 Free article. Review. No abstract available.

8

Elongation of the epiphyseal trabecular bone in transgenic mice carrying a klotho gene locus mutation that leads to a syndrome resembling aging.

Yamashita T, Nifuji A, Furuya K, Nabeshima Y, Noda M. Yamashita T, et al. J Endocrinol. 1998 Oct;159(1):1-8. doi: 10.1677/joe.0.1590001. J Endocrinol. 1998. PMID: 9795335 Review.

9

Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein.

Shiraki-Iida T, Aizawa H, Matsumura Y, Sekine S, Iida A, Anazawa H, Nagai R, Kuro-o M, Nabeshima Y. Shiraki-Iida T, et al. FEBS Lett. 1998 Mar 6;424(1-2):6-10. doi: 10.1016/s0014-5793(98)00127-6. FEBS Lett. 1998. PMID: 9537505 Free article.

10

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, Ohyama Y, Kurabayashi M, Kaname T, Kume E, Iwasaki H, Iida A, Shiraki-Iida T, Nishikawa S, Nagai R, Nabeshima YI. Kuro-o M, et al. Nature. 1997 Nov 6;390(6655):45-51. doi: 10.1038/36285. Nature. 1997. PMID: 9363890

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