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1988 2
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2023 4
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PubMed for id: 2624369696

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The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function - Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation.
Bull D, Matte JC, Navarron CM, McIntyre R, Whiting P, Katan M, Ducotterd F, Magno L. Bull D, et al. Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166978. doi: 10.1016/j.bbadis.2023.166978. Epub 2023 Dec 6. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38061598 Free article.
Human PLCG2 haploinsufficiency results in a novel natural killer cell immunodeficiency.
Alinger JB, Mace EM, Porter JR, Mah-Som AY, Daugherty AL, Li S, Throm AA, Pingel JT, Saucier N, Yao A, Chinn IK, Lupski JR, Ehlayel M, Keller M, Bowman GR, Cooper MA, Orange JS, French AR. Alinger JB, et al. J Allergy Clin Immunol. 2024 Jan;153(1):216-229. doi: 10.1016/j.jaci.2023.09.002. Epub 2023 Sep 13. J Allergy Clin Immunol. 2024. PMID: 37714437