Abstract
Muskelin is a novel intracellular protein, identified in mouse cells, that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin-1. We report that human muskelin is 98% identical with mouse muskelin at the amino acid level. The human muskelin gene is located at 7q32. The mouse muskelin gene maps syntenically at chromosome 6 B1/B2.
Copyright 1999 S. Karger AG, Basel
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Motifs
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Amino Acid Sequence
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Animals
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Cell Adhesion Molecules
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Chromosomes, Human, Pair 7 / genetics*
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Cloning, Molecular
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Conserved Sequence
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DNA, Complementary / genetics
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Expressed Sequence Tags
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Humans
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In Situ Hybridization, Fluorescence*
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Intracellular Signaling Peptides and Proteins
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Mice
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Molecular Sequence Data
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Open Reading Frames / genetics
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Physical Chromosome Mapping*
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Proteins / chemistry
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Proteins / genetics*
Substances
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Cell Adhesion Molecules
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DNA, Complementary
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Intracellular Signaling Peptides and Proteins
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MKLN1 protein, human
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Mkln1 protein, mouse
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Proteins