In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates

Antimicrob Agents Chemother. 2009 Sep;53(9):3996-4001. doi: 10.1128/AAC.00908-08. Epub 2009 Jul 6.

Abstract

The antimicrobial activities of telavancin and six comparators were evaluated against 460 isolates of anaerobic bacteria. Telavancin demonstrated excellent activity against gram-positive anaerobes (MIC90, 2 microg/ml) and was the most potent agent tested against Clostridium difficile (MIC90, 0.25 microg/ml). As expected, gram-negative isolates were not inhibited by telavancin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminoglycosides / pharmacology*
  • Anti-Bacterial Agents / pharmacology*
  • Bacteria, Anaerobic / drug effects*
  • Clostridioides difficile / drug effects
  • Gram-Negative Bacteria / drug effects
  • Gram-Positive Bacteria / drug effects
  • Lipoglycopeptides
  • Microbial Sensitivity Tests

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • Lipoglycopeptides
  • telavancin