PubMed (MeSH Keyword) for id: 11684

Year	Number of Results
1991	1
2003	1
2007	1
2008	1
2011	2
2012	1
2013	3
2014	3
2015	1
2016	3
2021	1
2023	2
2024	0

1

Selective Daily Mobility Bias in the Community Food Environment: Case Study of Greater Hartford, Connecticut.

Jin A, Chen X, Huang X, Li Z, Caspi CE, Xu R. Jin A, et al. Nutrients. 2023 Jan 13;15(2):404. doi: 10.3390/nu15020404. Nutrients. 2023. PMID: 36678275 Free PMC article.

2

Foetal haemoglobin inducers for reducing blood transfusion in non-transfusion-dependent beta-thalassaemias.

Foong WC, Loh CK, Ho JJ, Lau DS. Foong WC, et al. Cochrane Database Syst Rev. 2023 Jan 13;1(1):CD013767. doi: 10.1002/14651858.CD013767.pub2. Cochrane Database Syst Rev. 2023. PMID: 36637054 Free PMC article. Review.

3

Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia.

Armstrong AJ, Henke BR, Collado MS, Taylor JM, Pourtaheri TD, Dillberger JE, Roper TD, Wamhoff BR, Olson MW, Figler RA, Hoang SA, Reardon JE, Johns BA. Armstrong AJ, et al. J Med Chem. 2021 Apr 22;64(8):5037-5048. doi: 10.1021/acs.jmedchem.1c00124. Epub 2021 Apr 13. J Med Chem. 2021. PMID: 33848153 Free article.

4

Target-based drug discovery for [Formula: see text]-globin disorders: drug target prediction using quantitative modeling with hybrid functional Petri nets.

Mehraei M, Bashirov R, Tüzmen Ş. Mehraei M, et al. J Bioinform Comput Biol. 2016 Oct;14(5):1650026. doi: 10.1142/S0219720016500268. Epub 2016 Jun 21. J Bioinform Comput Biol. 2016. PMID: 27431020

5

Intrapatient variability in fetal hemoglobin measurements over time in sickle cell patients not on fetal hemoglobin inducing agents.

Knapp E, Cohen H, Kutlar A, Ghalie R, Manwani D. Knapp E, et al. Am J Hematol. 2016 Mar;91(3):E11-2. doi: 10.1002/ajh.24261. Am J Hematol. 2016. PMID: 26661045 Free article. No abstract available.

6

Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms.

Dai Y, Sangerman J, Luo HY, Fucharoen S, Chui DH, Faller DV, Perrine SP. Dai Y, et al. Blood Cells Mol Dis. 2016 Jan;56(1):62-9. doi: 10.1016/j.bcmd.2015.10.004. Epub 2015 Oct 27. Blood Cells Mol Dis. 2016. PMID: 26603726 Free PMC article.

7

A double-blind, placebo-controlled phase II study of the efficacy and safety of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease.

Reid ME, El Beshlawy A, Inati A, Kutlar A, Abboud MR, Haynes J Jr, Ward R, Sharon B, Taher AT, Smith W, Manwani D, Ghalie RG. Reid ME, et al. Am J Hematol. 2014 Jul;89(7):709-13. doi: 10.1002/ajh.23725. Epub 2014 Apr 15. Am J Hematol. 2014. PMID: 24677033 Free article. Clinical Trial.

8

A phase 2 trial of HQK-1001 in HbE-β thalassemia demonstrates HbF induction and reduced anemia.

Patthamalai P, Fuchareon S, Chaneiam N, Ghalie RG, Chui DH, Boosalis MS, Perrine SP. Patthamalai P, et al. Blood. 2014 Mar 20;123(12):1956-7. doi: 10.1182/blood-2013-11-538470. Blood. 2014. PMID: 24652964 Free PMC article. Clinical Trial. No abstract available.

9

A phase 2 study of HQK-1001, an oral fetal haemoglobin inducer, in β-thalassaemia intermedia.

Inati A, Kahale M, Perrine SP, Chui DH, Taher AT, Koussa S, Abi Nasr T, Abbas HA, Ghalie RG. Inati A, et al. Br J Haematol. 2014 Feb;164(3):456-8. doi: 10.1111/bjh.12635. Epub 2013 Nov 13. Br J Haematol. 2014. PMID: 24224649 Free PMC article. Clinical Trial. No abstract available.

10

A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease.

Kutlar A, Reid ME, Inati A, Taher AT, Abboud MR, El-Beshlawy A, Buchanan GR, Smith H, Ataga KI, Perrine SP, Ghalie RG. Kutlar A, et al. Am J Hematol. 2013 Nov;88(11):E255-60. doi: 10.1002/ajh.23533. Epub 2013 Oct 3. Am J Hematol. 2013. PMID: 23828223 Free article. Clinical Trial.

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