PubMed (MeSH Keyword) for id: 4098

Year	Number of Results
1948	2
1949	6
1950	6
1951	3
1952	1
1953	1
1954	1
1955	2
1956	1
1957	1
1958	1
1959	1
1961	1
1962	6
1963	2
1964	1
1967	1
1974	1
1975	4
1976	6
1977	3
1978	4
1979	6
1980	3
1981	4
1982	7
1983	8
1984	9
1985	5
1986	6
1987	8
1988	7
1989	6
1990	4
1991	3
1992	7
1993	3
1994	3
1995	2
1996	2
1998	2
2000	1
2001	2
2002	4
2003	1
2004	4
2006	2
2007	1
2008	4
2009	1
2010	2
2011	2
2012	2
2013	1
2014	1
2015	1
2016	1
2017	4
2018	2
2019	1
2020	1
2023	2
2024	2

1

Application of duplex sequencing to evaluate mutagenicity of aristolochic acid and methapyrilene in Fisher 344 rats.

Sahib S, Yan J, Chen T. Sahib S, et al. Food Chem Toxicol. 2024 Mar;185:114512. doi: 10.1016/j.fct.2024.114512. Epub 2024 Feb 9. Food Chem Toxicol. 2024. PMID: 38342231

2

Development of a single mobile phase for LC-IM-MS-based discovery lipidomics and metabolic phenotyping: Application to methapyrilene hepatotoxicity in the rat.

Wilson ID, Broeckling C, Gethings LA, Munjoma NC, Trengove R, Rainville PD, Lai SK, Isaac G, Plumb RS. Wilson ID, et al. J Chromatogr A. 2024 Jan 11;1714:464552. doi: 10.1016/j.chroma.2023.464552. Epub 2023 Dec 10. J Chromatogr A. 2024. PMID: 38113579

3

Effect of microsampling (50 μL) on toxicological evaluation of methapyrilene, a hepatotoxic substance, in a collaborative 28-day study in female rats.

Hattori N, Yokoyama H, Takumi A, Kawaguchi S, Yamaguchi K, Shimazaki T, Shibui Y, Saito K, Saito Y. Hattori N, et al. J Toxicol Sci. 2023;48(1):1-14. doi: 10.2131/jts.48.1. J Toxicol Sci. 2023. PMID: 36599423 Free article.

4

Downregulation of low-density lipoprotein receptor class A domain-containing protein 4 (Ldlrad4) in the liver of rats treated with nongenotoxic hepatocarcinogen to induce transforming growth factor β signaling promoting cell proliferation and suppressing apoptosis in early hepatocarcinogenesis.

Ito Y, Nakajima K, Masubuchi Y, Kikuchi S, Okano H, Saito F, Akahori Y, Jin M, Yoshida T, Shibutani M. Ito Y, et al. J Appl Toxicol. 2020 Nov;40(11):1467-1479. doi: 10.1002/jat.3998. Epub 2020 Jun 28. J Appl Toxicol. 2020. PMID: 32596862

5

In vitro proteomic analysis of methapyrilene toxicity in rat hepatocytes reveals effects on intermediary metabolism.

Braeuning A, Oberemm A, Heise T, Gundert-Remy U, Hengstler JG, Lampen A. Braeuning A, et al. Arch Toxicol. 2019 Feb;93(2):369-383. doi: 10.1007/s00204-018-2360-3. Epub 2018 Nov 22. Arch Toxicol. 2019. PMID: 30467583

6

Effect of aflatoxin B₁, benzo[a]pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells.

Tryndyak V, Kindrat I, Dreval K, Churchwell MI, Beland FA, Pogribny IP. Tryndyak V, et al. Food Chem Toxicol. 2018 Nov;121:214-223. doi: 10.1016/j.fct.2018.08.034. Epub 2018 Aug 26. Food Chem Toxicol. 2018. PMID: 30157460

7

Effect of methapyrilene hydrochloride on hepatic intracellular iron metabolism in vivo and in vitro.

Kindrat I, Dreval K, Shpyleva S, Tryndyak V, de Conti A, Mudalige TK, Chen T, Erstenyuk AM, Beland FA, Pogribny IP. Kindrat I, et al. Toxicol Lett. 2017 Nov 5;281:65-73. doi: 10.1016/j.toxlet.2017.09.011. Epub 2017 Sep 19. Toxicol Lett. 2017. PMID: 28935588

8

B-13 progenitor-derived hepatocytes (B-13/H cells) model lipid dysregulation in response to drugs and chemicals.

Leitch AC, Probert PME, Shayman JA, Meyer SK, Kass GEN, Wright MC. Leitch AC, et al. Toxicology. 2017 Jul 1;386:120-132. doi: 10.1016/j.tox.2017.05.014. Epub 2017 May 26. Toxicology. 2017. PMID: 28552552 Free PMC article.

9

Quantitative targeted bile acid profiling as new markers for DILI in a model of methapyrilene-induced liver injury in rats.

Slopianka M, Herrmann A, Pavkovic M, Ellinger-Ziegelbauer H, Ernst R, Mally A, Keck M, Riefke B. Slopianka M, et al. Toxicology. 2017 Jul 1;386:1-10. doi: 10.1016/j.tox.2017.05.009. Epub 2017 May 19. Toxicology. 2017. PMID: 28529062

10

Editor's Highlight: Organ-Specific Epigenetic Changes Induced by the Nongenotoxic Liver Carcinogen Methapyrilene in Fischer 344 Rats.

Shpyleva S, Dreval K, de Conti A, Kindrat I, Melnyk S, Yan J, Chen T, Beland FA, Pogribny IP. Shpyleva S, et al. Toxicol Sci. 2017 Mar 1;156(1):190-198. doi: 10.1093/toxsci/kfw242. Toxicol Sci. 2017. PMID: 28013212

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