Variation within the vat(E) allele of Enterococcus faecium isolates from retail poultry samples

S Simjee; P F McDermott; D D Wagner; D G White

doi:10.1128/AAC.45.10.2931-2932.2001

Variation within the vat(E) allele of Enterococcus faecium isolates from retail poultry samples

Antimicrob Agents Chemother. 2001 Oct;45(10):2931-2. doi: 10.1128/AAC.45.10.2931-2932.2001.

Authors

S Simjee¹, P F McDermott, D D Wagner, D G White

Affiliation

¹ Division of Animal and Food Microbiology, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD 20708, USA. ssimjee@cvm.fda.gov

Abstract

In a survey of retail meat samples, twelve quinupristin-dalfopristin-resistant (MICs, > or =4 mg/liter) Enterococcus faecium isolates that carried a vat(E) gene were recovered. DNA sequence comparison revealed five new variations in the vat(E) allele among 12 isolates, which were designated vat(E-4) through vat(E-8); two isolates had vat(E-1). There was no correlation between the number of base changes and the quinupristin-dalfopristin MIC.

MeSH terms

Acetyltransferases*
Alleles
Amino Acid Sequence
Animals
Bacterial Proteins / genetics*
Drug Resistance, Bacterial / genetics
Enterococcus faecium / genetics*
Enterococcus faecium / isolation & purification
Genetic Variation
Molecular Sequence Data
Poultry Products / microbiology*
Sequence Homology, Amino Acid

Substances

Bacterial Proteins
Acetyltransferases
streptogramin A acetyltransferase, Enterococcus faecium

Associated data

GENBANK/AY043209
GENBANK/AY043210
GENBANK/AY043211
GENBANK/AY043212
GENBANK/AY043213