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PubMed for id: 253722456
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Crystal structure of fibrinogen-Aalpha peptide 1-23 (F8Y) bound to bovine thrombin explains why the mutation of Phe-8 to tyrosine strongly inhibits normal cleavage at Arg-16.
Biochem J. 1997 Sep 15;326 ( Pt 3)(Pt 3):815-22. doi: 10.1042/bj3260815.
Biochem J. 1997.
PMID: 9307032
Free PMC article.
Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen A alpha: geometry of the catalytic triad and interactions of the P1', P2', and P3' substrate residues.
Martin PD, Malkowski MG, DiMaio J, Konishi Y, Ni F, Edwards BF.
Martin PD, et al.
Biochemistry. 1996 Oct 8;35(40):13030-9. doi: 10.1021/bi960656y.
Biochemistry. 1996.
PMID: 8855938
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