PubMed (RefSeq) for id: 8922792

Year	Number of Results
2002	1
2003	2
2004	3
2005	1
2006	1
2009	1
2010	1
2011	2
2012	1
2014	1
2015	9
2016	13
2017	14
2018	14
2019	11
2020	12
2021	16
2022	6
2023	4
2024	1

1

Association of NUDT15 gene polymorphism with adverse reaction, treatment efficacy, and dose of 6-mercaptopurine in patients with acute lymphoblastic leukemia: a systematic review and meta-analysis.

Du S, Huang X, He X, Mao M, Chen M, Zhang R, Shao H, Lv Z, Liu X, Chuan J. Du S, et al. Haematologica. 2024 Apr 1;109(4):1053-1068. doi: 10.3324/haematol.2023.282761. Haematologica. 2024. PMID: 37794799 Free PMC article.

2

The c.415C>T polymorphism in NUDT15 is more frequent than the polymorphisms in TPMT in Chilean patients who use thiopurine drugs.

von Muhlenbrock C, Estay C, Covarrubias N, Miranda J, Venegas M. von Muhlenbrock C, et al. Pharmacogenet Genomics. 2023 Sep 1;33(7):161-163. doi: 10.1097/FPC.0000000000000503. Epub 2023 Aug 2. Pharmacogenet Genomics. 2023. PMID: 37556121

3

Analysis of the NUDT15 gene and metabolites of azathioprine in Japanese patients with inflammatory bowel disease.

Suzuki S, Uchiyama K, Motoi Y, Yoshii Y, Inoue Y, Kubota T, Odahara S, Ohtaki Y, Takami S, Ito Z, Sato N, Ohkusa T, Koido S, Saruta M. Suzuki S, et al. BMC Gastroenterol. 2023 Jul 15;23(1):239. doi: 10.1186/s12876-023-02881-6. BMC Gastroenterol. 2023. PMID: 37454061 Free PMC article.

4

The influence of NUDT15 variants on 6-mercaptopurine-induced neutropenia in Vietnamese pediatric acute lymphoblastic leukemia.

Nguyen ML, Hoang AV, Duong BT, Phung NTN. Nguyen ML, et al. HGG Adv. 2023 Feb 10;4(2):100183. doi: 10.1016/j.xhgg.2023.100183. eCollection 2023 Apr 13. HGG Adv. 2023. PMID: 36873097 Free PMC article.

5

Single-Nucleotide Polymorphisms, c.415C > T (Arg139Cys) and c.416G > A (Arg139His), in the NUDT15 Gene Are Associated with Thiopurine-Induced Leukopenia.

Isono T, Hira D, Ikeda Y, Kawahara M, Noda S, Nishida A, Inatomi O, Fujimoto N, Andoh A, Terada T, Morita SY. Isono T, et al. Biol Pharm Bull. 2023;46(3):412-418. doi: 10.1248/bpb.b22-00686. Biol Pharm Bull. 2023. PMID: 36858569 Free article.

6

Prominence of NUDT15 genetic variation associated with 6-mercaptopurine tolerance in a genome-wide association study of Japanese children with acute lymphoblastic leukaemia.

Tanaka Y, Urayama KY, Mori M, Arakawa Y, Hasegawa D, Noguchi Y, Yanagimachi M, Keino D, Ota S, Akahane K, Inukai T, Hangai M, Kawaguchi T, Takagi M, Koh K, Matsuda F, Manabe A. Tanaka Y, et al. Br J Haematol. 2022 Oct;199(2):260-269. doi: 10.1111/bjh.18405. Epub 2022 Aug 12. Br J Haematol. 2022. PMID: 35961941 Free article.

7

XDH genotypes through gene-gene interactions with NUDT15 affect azathioprine-induced leukopenia in Chinese patients.

Liu J, Wen Z, Huang S, Zhang X, Ai X, Qian J. Liu J, et al. Pharmacogenomics. 2022 Aug;23(12):671-682. doi: 10.2217/pgs-2022-0063. Epub 2022 Aug 2. Pharmacogenomics. 2022. PMID: 35916133

8

Low NUDT15 expression levels due to biallelic NUDT15 variants and 6-mercaptopurine intolerance.

Yoshida M, Brown SA, Moriyama T, Nishii R, Tsujimoto SI, Yamada Y, Yoshida K, Shirai R, Osumi T, Utano T, Fukano R, Kudo K, Sakaguchi K, Arakawa Y, Koh K, Sekiguchi M, Sekimizu M, Miyamura T, Ishida H, Inukai T, Tomizawa D, Kiyokawa N, Kato M, Yang JJ. Yoshida M, et al. Br J Haematol. 2022 Oct;199(2):270-276. doi: 10.1111/bjh.18375. Epub 2022 Jul 29. Br J Haematol. 2022. PMID: 35905175 Free PMC article.

9

Susceptibility to thiopurine toxicity by TPMT and NUDT15 variants in Colombian children with acute lymphoblastic leukemia.

Correa-Jimenez O, Yunis JJ, Linares-Ballesteros A, Sarmiento-Urbina I. Correa-Jimenez O, et al. Colomb Med (Cali). 2021 Sep 30;52(3):e2074569. doi: 10.25100/cm.v52i3.4569. eCollection 2021 Jul-Sep. Colomb Med (Cali). 2021. PMID: 35431360 Free PMC article.

10

Nudix hydrolase 15 (NUDT15) loss-of-function variants in an Australian inflammatory bowel disease population.

Afrin S, Simms LA, Lord A, Radford-Smith GL. Afrin S, et al. Intern Med J. 2022 Nov;52(11):1971-1977. doi: 10.1111/imj.15746. Epub 2022 Jun 8. Intern Med J. 2022. PMID: 35289057 Free PMC article.

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