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Herbal Formula Fo Shou San Attenuates Alzheimer's Disease-Related Pathologies via the Gut-Liver-Brain Axis in APP/PS1 Mouse Model of Alzheimer's Disease.

Lu J, Guo P, Liu X, Zhang Y, Guo X, Gao X, Chen Y.

Evid Based Complement Alternat Med. 2019 Jun 17;2019:8302950. doi: 10.1155/2019/8302950. eCollection 2019.


Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation.

Zhou J, Yu W, Zhang M, Tian X, Li Y, Lü Y.

Neurochem Res. 2019 May;44(5):1138-1151. doi: 10.1007/s11064-019-02748-x. Epub 2019 Feb 12.


Quantitative proteomics reveals that PEA15 regulates astroglial Aβ phagocytosis in an Alzheimer's disease mouse model.

Lv J, Ma S, Zhang X, Zheng L, Ma Y, Zhao X, Lai W, Shen H, Wang Q, Ji J.

J Proteomics. 2014 Oct 14;110:45-58. doi: 10.1016/j.jprot.2014.07.028. Epub 2014 Aug 7.


Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice.

Gong Z, Huang J, Xu B, Ou Z, Zhang L, Lin X, Ye X, Kong X, Long D, Sun X, He X, Xu L, Li Q, Xuan A.

J Neuroinflammation. 2019 Mar 14;16(1):62. doi: 10.1186/s12974-019-1450-3.


Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer's disease.

Agostini A, Yuchun D, Li B, Kendall DA, Pardon MC.

Brain Behav Immun. 2019 Sep 24. pii: S0889-1591(19)30375-7. doi: 10.1016/j.bbi.2019.09.019. [Epub ahead of print]


Alzheimer's Disease Histological and Behavioral Manifestations in Transgenic Mice Correlate with Specific Gut Microbiome State.

Shen L, Liu L, Ji HF.

J Alzheimers Dis. 2017;56(1):385-390. doi: 10.3233/JAD-160884.


Fo Shou San, an ancient Chinese herbal decoction, protects endothelial function through increasing endothelial nitric oxide synthase activity.

Bi CW, Xu L, Tian XY, Liu J, Zheng KY, Lau CW, Lau DT, Choi RC, Dong TT, Huang Y, Tsim KW.

PLoS One. 2012;7(12):e51670. doi: 10.1371/journal.pone.0051670. Epub 2012 Dec 21.


Curcumin Ameliorates Memory Deficits by Enhancing Lactate Content and MCT2 Expression in APP/PS1 Transgenic Mouse Model of Alzheimer's Disease.

Lu WT, Sun SQ, Li Y, Xu SY, Gan SW, Xu J, Qiu GP, Zhuo F, Huang SQ, Jiang XL, Huang J.

Anat Rec (Hoboken). 2019 Feb;302(2):332-338. doi: 10.1002/ar.23969. Epub 2018 Nov 9.


Effective expression of Drebrin in hippocampus improves cognitive function and alleviates lesions of Alzheimer's disease in APP (swe)/PS1 (ΔE9) mice.

Liu Y, Xu YF, Zhang L, Huang L, Yu P, Zhu H, Deng W, Qin C.

CNS Neurosci Ther. 2017 Jul;23(7):590-604. doi: 10.1111/cns.12706. Epub 2017 Jun 8.


6-Methyluracil derivatives as acetylcholinesterase inhibitors for treatment of Alzheimer's disease.

Zueva IV, Semenov VE, Mukhamedyarov MA, Lushchekina SV, Kharlamova AD, Petukhova EO, Mikhailov AS, Podyachev SN, Saifina LF, Petrov KA, Minnekhanova OA, Zobov VV, Nikolsky EE, Masson P, Reznik VS.

Int J Risk Saf Med. 2015;27 Suppl 1:S69-71. doi: 10.3233/JRS-150694.


Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease.

Lee KI, Lee HT, Lin HC, Tsay HJ, Tsai FC, Shyue SK, Lee TS.

J Neuroinflammation. 2016 Apr 27;13(1):92. doi: 10.1186/s12974-016-0557-z.


ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice.

Button EB, Boyce GK, Wilkinson A, Stukas S, Hayat A, Fan J, Wadsworth BJ, Robert J, Martens KM, Wellington CL.

Alzheimers Res Ther. 2019 May 13;11(1):44. doi: 10.1186/s13195-019-0497-9.


Effects of accelerated senescence on learning and memory, locomotion and anxiety-like behavior in APP/PS1 mouse model of Alzheimer's disease.

Lok K, Zhao H, Zhang C, He N, Shen H, Wang Z, Zhao W, Yin M.

J Neurol Sci. 2013 Dec 15;335(1-2):145-54. doi: 10.1016/j.jns.2013.09.018. Epub 2013 Sep 21.


[Moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in APP/PS1 transgenic Alzheimer's disease mice].

Zhu CF, Zhang LD, Song XG, Yang J, Pan HP, He CG, Yang K, Qin XF, Zhu WL.

Zhen Ci Yan Jiu. 2019 Apr 25;44(4):235-41. doi: 10.13702/j.1000-0607.180305. Chinese.


Characterization of the APP/PS1 mouse model of Alzheimer's disease in senescence accelerated background.

Lok K, Zhao H, Shen H, Wang Z, Gao X, Zhao W, Yin M.

Neurosci Lett. 2013 Dec 17;557 Pt B:84-9. doi: 10.1016/j.neulet.2013.10.051. Epub 2013 Oct 28.


Huatuo Zaizao pill ameliorates cognitive impairment of APP/PS1 transgenic mice by improving synaptic plasticity and reducing Aβ deposition.

Zhang JH, Yu LJ, Yang H, Hui Z, Jiang S, Chen L, Zhao Y, Wang SL, Liu Y, Xu Y.

BMC Complement Altern Med. 2018 May 29;18(1):167. doi: 10.1186/s12906-018-2237-2.


Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an Alzheimer's disease model mouse.

Chung E, Ji Y, Sun Y, Kascsak RJ, Kascsak RB, Mehta PD, Strittmatter SM, Wisniewski T.

BMC Neurosci. 2010 Oct 14;11:130. doi: 10.1186/1471-2202-11-130.


Ligustilide Ameliorates Memory Deficiency in APP/PS1 Transgenic Mice via Restoring Mitochondrial Dysfunction.

Xu YJ, Mei Y, Qu ZL, Zhang SJ, Zhao W, Fang JS, Wu J, Yang C, Liu SJ, Fang YQ, Wang Q, Zhang YB.

Biomed Res Int. 2018 Jul 10;2018:4606752. doi: 10.1155/2018/4606752. eCollection 2018.

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