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Year Number of Results
1945 28
1946 225
1947 199
1948 212
1949 121
1950 55
1951 519
1952 1476
1953 1783
1954 1974
1955 2150
1956 2072
1957 2336
1958 2486
1959 1285
1960 46
1961 71
1962 92
1963 176
1964 608
1965 3656
1966 7400
1967 8498
1968 10009
1969 11293
1970 12490
1971 13119
1972 15129
1973 17553
1974 18412
1975 18668
1976 18768
1977 17976
1978 18723
1979 20684
1980 21386
1981 22533
1982 25153
1983 27616
1984 29505
1985 30862
1986 31518
1987 33226
1988 34808
1989 38317
1990 40900
1991 41449
1992 42698
1993 46104
1994 51392
1995 54420
1996 57500
1997 60458
1998 64628
1999 68321
2000 72409
2001 76519
2002 81614
2003 89651
2004 94934
2005 103808
2006 109119
2007 115244
2008 122809
2009 130629
2010 141487
2011 154444
2012 164548
2013 174112
2014 180308
2015 183011
2016 186533
2017 192384
2018 198512
2019 204764
2020 216235
2021 213119
2022 200493
2023 175895
2024 55451

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4,226,433 results

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Page 1
Randomization in clinical studies.
Lim CY, In J. Lim CY, et al. Korean J Anesthesiol. 2019 Jun;72(3):221-232. doi: 10.4097/kja.19049. Epub 2019 Apr 1. Korean J Anesthesiol. 2019. PMID: 30929415 Free PMC article. Review.
Randomized controlled trial is widely accepted as the best design for evaluating the efficacy of a new treatment because of the advantages of randomization (random allocation). ...Despite its importance, randomization has not been properly under …
Randomized controlled trial is widely accepted as the best design for evaluating the efficacy of a new treatment because of th …
Blocked randomization with randomly selected block sizes.
Efird J. Efird J. Int J Environ Res Public Health. 2011 Jan;8(1):15-20. doi: 10.3390/ijerph8010015. Epub 2010 Dec 23. Int J Environ Res Public Health. 2011. PMID: 21318011 Free PMC article.
When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. ...However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the …
When planning a randomized clinical trial, careful consideration must be given to how participants are selected for var …
Evaluating treatment effectiveness.
Andrews G. Andrews G. Aust N Z J Psychiatry. 1989 Jun;23(2):181-6. doi: 10.3109/00048678909062134. Aust N Z J Psychiatry. 1989. PMID: 2673195 Review.
When deciding which treatments are of benefit, results from placebo-controlled trials are conventionally preferred above all others, and treatments not supported by such trials are viewed sceptically. In this paper it is argued that while randomised controlled trials are d …
When deciding which treatments are of benefit, results from placebo-controlled trials are conventionally preferred above all others, and tre …
Single-patient trials.
[No authors listed] [No authors listed] Lancet. 1986 May 31;1(8492):1254-5. Lancet. 1986. PMID: 2872397
The Department of Clinical Epidemiology and Biostatistics at McMaster University has devised formal protocols for single-patient randomized trials to help clinicians find the optimal treatment for individual patients. ...Patients and clinicians are "blinded," and su …
The Department of Clinical Epidemiology and Biostatistics at McMaster University has devised formal protocols for single-patient r …
Traditional and innovative experimental and clinical trial designs and their advantages and pitfalls.
Weimer K, Enck P. Weimer K, et al. Handb Exp Pharmacol. 2014;225:237-72. doi: 10.1007/978-3-662-44519-8_14. Handb Exp Pharmacol. 2014. PMID: 25304536 Review.
Many study designs and design variants have been developed in the past to either overcome or enhance drug-placebo differences in clinical trials or to identify and characterize placebo responders in experimental studies. ...
Many study designs and design variants have been developed in the past to either overcome or enhance drug-placebo differences in clinical …
Randomized controlled trials.
Schulz KF. Schulz KF. Clin Obstet Gynecol. 1998 Jun;41(2):245-56. doi: 10.1097/00003081-199806000-00005. Clin Obstet Gynecol. 1998. PMID: 9646957 Review. No abstract available.
Cluster randomised trials.
Barbui C, Cipriani A. Barbui C, et al. Epidemiol Psychiatr Sci. 2011 Dec;20(4):307-9. doi: 10.1017/s2045796011000515. Epidemiol Psychiatr Sci. 2011. PMID: 22201207 Review.
Although randomised controlled trials are the reference methodology to assess the effects of therapeutic interventions, for interventions that naturally occur in groups of individuals random allocation of participants may be inappropriate. ...Clinical trials …
Although randomised controlled trials are the reference methodology to assess the effects of therapeutic interventions, for intervent …
Random allocation in controlled clinical trials: a review.
Egbewale BE. Egbewale BE. J Pharm Pharm Sci. 2014;17(2):248-53. doi: 10.18433/j3sw36. J Pharm Pharm Sci. 2014. PMID: 24934553 Free article. Review.
In some circles, opinions are also divided on the strength and weaknesses of each of the random allocation strategies. This review provides an update on various random allocation techniques so as to correct existing misconceptions on this all important procedure. ME …
In some circles, opinions are also divided on the strength and weaknesses of each of the random allocation strategies. This review pr …
Anticoagulant therapy in cerebrovascular disease: review and meta-analysis.
Jonas S. Jonas S. Stroke. 1988 Aug;19(8):1043-8. doi: 10.1161/01.str.19.8.1043. Stroke. 1988. PMID: 3041650 Review.
Sixteen acceptably randomized studies of anticoagulant therapy after cerebral or retinal ischemia or infarction are reviewed and the results among 1,046 anticoagulated patients and 1,071 controls are analyzed. ...
Sixteen acceptably randomized studies of anticoagulant therapy after cerebral or retinal ischemia or infarction are reviewed and the …
Randomization methods in emergency setting trials: a descriptive review.
Corbett MS, Moe-Byrne T, Oddie S, McGuire W. Corbett MS, et al. Res Synth Methods. 2016 Mar;7(1):46-54. doi: 10.1002/jrsm.1163. Epub 2015 Sep 2. Res Synth Methods. 2016. PMID: 26333419 Free PMC article. Review.
Clinical heterogeneity and poor reporting limited the assessment of trial recruitment outcomes. ...Clinical heterogeneity across trials within reviews, coupled with limited availability of relevant trial accrual data, meant it was not possible to adequ …
Clinical heterogeneity and poor reporting limited the assessment of trial recruitment outcomes. ...Clinical heterogenei …
4,226,433 results
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