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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 3
1978 3
1979 4
1980 4
1982 3
1983 5
1984 2
1985 8
1986 4
1987 8
1988 9
1989 2
1990 10
1991 8
1992 10
1993 16
1994 10
1995 17
1996 8
1997 8
1998 11
1999 16
2000 7
2001 10
2002 17
2003 11
2004 10
2005 13
2006 21
2007 13
2008 20
2009 7
2010 14
2011 18
2012 13
2013 15
2014 17
2015 17
2016 14
2017 14
2018 17
2019 19
2020 22
2021 23
2022 25
2023 14
2024 3

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497 results

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Page 1
Delayed puberty.
Butler G, Purushothaman P. Butler G, et al. Minerva Pediatr. 2020 Dec;72(6):484-490. doi: 10.23736/S0026-4946.20.05968-X. Epub 2020 Aug 4. Minerva Pediatr. 2020. PMID: 32748610 Review.
The onset of puberty may be late - in the latter part of the predicted normal range or truly delayed - beyond this range. The latest age to start is usually regarded as 13 years in girls and 14 years in boys. ...Counselling, reassurance and support are key elements in the …
The onset of puberty may be late - in the latter part of the predicted normal range or truly delayed - beyond this range. The latest …
Management of hypogonadism from birth to adolescence.
Howard SR, Dunkel L. Howard SR, et al. Best Pract Res Clin Endocrinol Metab. 2018 Aug;32(4):355-372. doi: 10.1016/j.beem.2018.05.011. Epub 2018 Jun 6. Best Pract Res Clin Endocrinol Metab. 2018. PMID: 30086863 Review.
Management of patients with hypogonadism is dependent on the underlying cause. Whilst functional hypogonadism presenting as delayed puberty in adolescence is relatively common, permanent hypogonadism presenting in infancy or adolescence is unusual. The main differen …
Management of patients with hypogonadism is dependent on the underlying cause. Whilst functional hypogonadism presenting as delayed …
Sex Steroid and Gonadotropin Treatment in Male Delayed Puberty.
Howard S, Dunkel L. Howard S, et al. Endocr Dev. 2016;29:185-97. doi: 10.1159/000438891. Epub 2015 Dec 17. Endocr Dev. 2016. PMID: 26680579 Review.
Male delayed puberty is common, affecting up to 3% of the population. Management of patients with pubertal delay is dependent on the underlying cause. The main differential diagnoses of delayed puberty in males include constitutional delay of growth an …
Male delayed puberty is common, affecting up to 3% of the population. Management of patients with pubertal delay is dependent …
Prevalence of Deleterious Variants in MC3R in Patients With Constitutional Delay of Growth and Puberty.
Duckett K, Williamson A, Kincaid JWR, Rainbow K, Corbin LJ, Martin HC, Eberhardt RY, Huang QQ, Hurles ME, He W, Brauner R, Delaney A, Dunkel L, Grinspon RP, Hall JE, Hirschhorn JN, Howard SR, Latronico AC, Jorge AAL, McElreavey K, Mericq V, Merino PM, Palmert MR, Plummer L, Rey RA, Rezende RC, Seminara SB, Salnikov K, Banerjee I, Lam BYH, Perry JRB, Timpson NJ, Clayton P, Chan YM, Ong KK, O'Rahilly S. Duckett K, et al. J Clin Endocrinol Metab. 2023 Nov 17;108(12):e1580-e1587. doi: 10.1210/clinem/dgad373. J Clin Endocrinol Metab. 2023. PMID: 37339320 Free PMC article.
METHODS: We examined the sequence of MC3R in 362 adolescents with a clinical diagnosis of CDGP and 657 patients with nIHH, experimentally characterized the signaling properties of all nonsynonymous variants found and compared their frequency to that in 5774 controls from a popula …
METHODS: We examined the sequence of MC3R in 362 adolescents with a clinical diagnosis of CDGP and 657 patients with nIHH, experimentally ch …
Clinical Profile of Adolescents With Delayed Puberty.
Selvaraj A, Prasad HK, Narayanasamy K, Thiagarajan A, Nedunchelian K. Selvaraj A, et al. Indian Pediatr. 2021 Jul 15;58(7):684-685. Epub 2021 Apr 17. Indian Pediatr. 2021. PMID: 33864448 Free article.
One year study on forty-eight adolescents with delayed puberty revealed etiology of constitutional delay, hypogonadotrophic hypogonadism (HH), hypergonadotrophic hypogonadism, chronic systemic disease, hypothyroidism and sex reversal in 14(29.2%), 13 (27%), 12 (25%) …
One year study on forty-eight adolescents with delayed puberty revealed etiology of constitutional delay, hypogonadotrophic hy …
Pubertal abnormalities in adolescents with chronic disease.
Kao KT, Denker M, Zacharin M, Wong SC. Kao KT, et al. Best Pract Res Clin Endocrinol Metab. 2019 Jun;33(3):101275. doi: 10.1016/j.beem.2019.04.009. Epub 2019 Apr 19. Best Pract Res Clin Endocrinol Metab. 2019. PMID: 31047817 Review.
In these adolescents, impaired skeletal development is also observed and this can be associated with fragility fractures. Chronic inflammation, glucocorticoid and sub-optimal nutrition all impact on the hypothalamic-pituitary gonadal axis, and can also impact on skeletal d …
In these adolescents, impaired skeletal development is also observed and this can be associated with fragility fractures. Chronic inf …
Pubertal disorders and bone maturation.
Lazar L, Phillip M. Lazar L, et al. Endocrinol Metab Clin North Am. 2012 Dec;41(4):805-25. doi: 10.1016/j.ecl.2012.08.003. Endocrinol Metab Clin North Am. 2012. PMID: 23099272 Review.
Bone age (BA) indicates more clearly than chronologic age how far an individual has progressed toward full maturity, and predicts the potential for further growth. Single or serial skeletal age estimations help to confirm the diagnosis of normal puberty and normal pubertal …
Bone age (BA) indicates more clearly than chronologic age how far an individual has progressed toward full maturity, and predicts the …
Key features of puberty onset and progression can help distinguish self-limited delayed puberty from congenital hypogonadotrophic hypogonadism.
Aung Y, Kokotsis V, Yin KN, Banerjee K, Butler G, Dattani MT, Dimitri P, Dunkel L, Hughes C, McGuigan M, Korbonits M, Paltoglou G, Sakka S, Shah P, Storr HL, Willemsen RH, Howard SR. Aung Y, et al. Front Endocrinol (Lausanne). 2023 Aug 28;14:1226839. doi: 10.3389/fendo.2023.1226839. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37701896 Free PMC article.
INTRODUCTION: Delayed puberty (DP) is a frequent concern for adolescents. The most common underlying aetiology is self-limited DP (SLDP). ...However, the distinction between HH, particularly partial HH, and SLDP remains problematic. Further research into an integrat …
INTRODUCTION: Delayed puberty (DP) is a frequent concern for adolescents. The most common underlying aetiology is self-limited …
Growth, puberty, and bone health in children and adolescents with inflammatory bowel disease.
Jin HY, Lim JS, Lee Y, Choi Y, Oh SH, Kim KM, Yoo HW, Choi JH. Jin HY, et al. BMC Pediatr. 2021 Jan 14;21(1):35. doi: 10.1186/s12887-021-02496-4. BMC Pediatr. 2021. PMID: 33446154 Free PMC article.
BACKGROUND: Endocrine complications such as impaired growth, delayed puberty, and low bone mineral density (BMD) can be associated with inflammatory bowel disease (IBD) in children and adolescents. ...Among 109 patients who were older than 13 (girls) or 14 (boys) ye …
BACKGROUND: Endocrine complications such as impaired growth, delayed puberty, and low bone mineral density (BMD) can be associ …
Update on the Genetics of Idiopathic Hypogonadotropic Hypogonadism.
Topaloğlu AK. Topaloğlu AK. J Clin Res Pediatr Endocrinol. 2017 Dec 30;9(Suppl 2):113-122. doi: 10.4274/jcrpe.2017.S010. Epub 2017 Dec 27. J Clin Res Pediatr Endocrinol. 2017. PMID: 29280744 Free PMC article. Review.
Moreover, there may be an overlap or transition between constitutional delay in growth and puberty (CDGP) and IHH. It has been increasingly observed that oligogenic inheritance and clinical recovery complicates the phenotype/genotype relationship in IHH, thus making it cha …
Moreover, there may be an overlap or transition between constitutional delay in growth and puberty (CDGP) and IHH. It has been increasingly …
497 results