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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1956 1
1964 1
1965 1
1966 3
1968 1
1969 4
1970 2
1971 10
1972 5
1973 6
1974 7
1975 10
1976 16
1977 22
1978 31
1979 21
1980 38
1981 37
1982 36
1983 38
1984 34
1985 27
1986 29
1987 31
1988 29
1989 38
1990 23
1991 48
1992 33
1993 46
1994 34
1995 30
1996 55
1997 40
1998 43
1999 59
2000 54
2001 62
2002 38
2003 62
2004 48
2005 72
2006 62
2007 72
2008 77
2009 81
2010 96
2011 98
2012 123
2013 134
2014 120
2015 118
2016 116
2017 140
2018 128
2019 149
2020 131
2021 108
2022 107
2023 84
2024 27

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2,816 results

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Page 1
Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.
Hundscheid T, Onland W, Kooi EMW, Vijlbrief DC, de Vries WB, Dijkman KP, van Kaam AH, Villamor E, Kroon AA, Visser R, Mulder-de Tollenaer SM, De Bisschop B, Dijk PH, Avino D, Hocq C, Zecic A, Meeus M, de Baat T, Derriks F, Henriksen TB, Kyng KJ, Donders R, Nuytemans DHGM, Van Overmeire B, Mulder AL, de Boode WP; BeNeDuctus Trial Investigators. Hundscheid T, et al. N Engl J Med. 2023 Mar 16;388(11):980-990. doi: 10.1056/NEJMoa2207418. Epub 2022 Dec 6. N Engl J Med. 2023. PMID: 36477458 Clinical Trial.
BACKGROUND: Cyclooxygenase inhibitors are commonly used in infants with patent ductus arteriosus (PDA), but the benefit of these drugs is uncertain. METHODS: In this multicenter, noninferiority trial, we randomly assigned infants with echocardio …
BACKGROUND: Cyclooxygenase inhibitors are commonly used in infants with patent ductus arteriosus (PDA), but the benefit …
Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis.
Mitra S, Florez ID, Tamayo ME, Mbuagbaw L, Vanniyasingam T, Veroniki AA, Zea AM, Zhang Y, Sadeghirad B, Thabane L. Mitra S, et al. JAMA. 2018 Mar 27;319(12):1221-1238. doi: 10.1001/jama.2018.1896. JAMA. 2018. PMID: 29584842 Free PMC article. Review.
IMPORTANCE: Despite increasing emphasis on conservative management of patent ductus arteriosus (PDA) in preterm infants, different pharmacotherapeutic interventions are used to treat those developing a hemodynamically significant PDA. ...RESULTS: In 68 ran …
IMPORTANCE: Despite increasing emphasis on conservative management of patent ductus arteriosus (PDA) in preterm infants …
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants.
Jasani B, Mitra S, Shah PS. Jasani B, et al. Cochrane Database Syst Rev. 2022 Dec 15;12:CD010061. doi: 10.1002/14651858.CD010061.pub5. Cochrane Database Syst Rev. 2022. PMID: 36519620 Review.
BACKGROUND: The different management strategies for patent ductus arteriosus (PDA) in preterm infants are expectant management, surgery, or medical treatment with non-selective cyclo-oxygenase inhibitors. Randomized controlled trials (RCTs) have sugges …
BACKGROUND: The different management strategies for patent ductus arteriosus (PDA) in preterm infants are expectant man …
Delayed vs early umbilical cord clamping for preterm infants: a systematic review and meta-analysis.
Fogarty M, Osborn DA, Askie L, Seidler AL, Hunter K, Lui K, Simes J, Tarnow-Mordi W. Fogarty M, et al. Am J Obstet Gynecol. 2018 Jan;218(1):1-18. doi: 10.1016/j.ajog.2017.10.231. Epub 2017 Oct 30. Am J Obstet Gynecol. 2018. PMID: 29097178 Review.
STUDY DESIGN: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Chinese articles, cross-referencing citations, expert informants, and trial registries to July 31, 2017, for randomized controlled trials of delayed (30 seconds) vs early …
STUDY DESIGN: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Chinese articles, cross-referencing citations …
Probiotics to prevent infantile colic.
Ong TG, Gordon M, Banks SS, Thomas MR, Akobeng AK. Ong TG, et al. Cochrane Database Syst Rev. 2019 Mar 13;3(3):CD012473. doi: 10.1002/14651858.CD012473.pub2. Cochrane Database Syst Rev. 2019. PMID: 30865287 Free PMC article.
Two studies began probiotics during pregnancy and continued administering them to the baby after birth.We considered the risk of bias for randomisation as low for all six trials; for allocation concealment as low in two studies and unclear in four others. All studies were …
Two studies began probiotics during pregnancy and continued administering them to the baby after birth.We considered the risk of bias for …
Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants.
Ohlsson A, Walia R, Shah SS. Ohlsson A, et al. Cochrane Database Syst Rev. 2020 Feb 11;2(2):CD003481. doi: 10.1002/14651858.CD003481.pub8. Cochrane Database Syst Rev. 2020. PMID: 32045960 Free PMC article.
BACKGROUND: Indomethacin is used as standard therapy to close a patent ductus arteriosus (PDA) but is associated with reduced blood flow to several organs. ...OBJECTIVES: To determine the effectiveness and safety of ibuprofen compared with indomethacin, other …
BACKGROUND: Indomethacin is used as standard therapy to close a patent ductus arteriosus (PDA) but is associated with r …
Early Amino Acids in Extremely Preterm Infants and Neurodisability at 2 Years.
Bloomfield FH, Jiang Y, Harding JE, Crowther CA, Cormack BE; ProVIDe Trial Group. Bloomfield FH, et al. N Engl J Med. 2022 Nov 3;387(18):1661-1672. doi: 10.1056/NEJMoa2204886. N Engl J Med. 2022. PMID: 36322845 Clinical Trial.
METHODS: In this multicenter, parallel-group, double-blind, randomized, placebo-controlled trial, we assigned infants with birth weights of less than 1000 g at 8 neonatal intensive care units to receive amino acids at a dose of 1 g per day (intervention group) or pl …
METHODS: In this multicenter, parallel-group, double-blind, randomized, placebo-controlled trial, we assigned infants with bir …
Comparative study of the efficacy and safety of paracetamol, ibuprofen, and indomethacin in closure of patent ductus arteriosus in preterm neonates.
El-Mashad AE, El-Mahdy H, El Amrousy D, Elgendy M. El-Mashad AE, et al. Eur J Pediatr. 2017 Feb;176(2):233-240. doi: 10.1007/s00431-016-2830-7. Epub 2016 Dec 21. Eur J Pediatr. 2017. PMID: 28004188 Clinical Trial.
In this prospective study, we compared the efficacy and side effects of indomethacin, ibuprofen, and paracetamol in patent ductus arteriosus (PDA) closure in preterm neonates. Three hundred preterm neonates with hemodynamically significant PDA (hs-PDA) admitt …
In this prospective study, we compared the efficacy and side effects of indomethacin, ibuprofen, and paracetamol in patent ductus …
Intravenous paracetamol in comparison with ibuprofen for the treatment of patent ductus arteriosus in preterm infants: a randomized controlled trial.
Dani C, Lista G, Bianchi S, Mosca F, Schena F, Ramenghi L, Zecca E, Vento G, Poggi C, Leonardi V, Minghetti D, Rosignoli MT, Calisti F, Comandini A, Cattaneo A, Lipone P. Dani C, et al. Eur J Pediatr. 2021 Mar;180(3):807-816. doi: 10.1007/s00431-020-03780-8. Epub 2020 Sep 4. Eur J Pediatr. 2021. PMID: 32888085 Free PMC article. Clinical Trial.
Our aim was to assess the efficacy and safety of intravenous (i.v.) paracetamol vs. i.v. ibuprofen for the treatment of hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infants. This is a multicenter randomized controlled study. …
Our aim was to assess the efficacy and safety of intravenous (i.v.) paracetamol vs. i.v. ibuprofen for the treatment of hemodynamically sign …
Platelets and ductus arteriosus closure in neonates.
Sallmon H, Delaney CA. Sallmon H, et al. Semin Perinatol. 2023 Mar;47(2):151719. doi: 10.1016/j.semperi.2023.151719. Epub 2023 Mar 1. Semin Perinatol. 2023. PMID: 36925318 Free article. Clinical Trial.
Neonatal platelets likely have multifaceted roles during ductal closure, such as secretion of several signaling molecules and facilitation of specific cell-cell interactions. The only available randomized-controlled trial on platelet transfusions in preterm infants …
Neonatal platelets likely have multifaceted roles during ductal closure, such as secretion of several signaling molecules and facilitation o …
2,816 results