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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2001 5
2002 8
2003 8
2004 17
2005 14
2006 4
2007 9
2008 15
2009 7
2010 6
2011 9
2012 9
2013 11
2014 8
2015 5
2016 3
2018 3
2019 3
2020 1
2021 1
2023 1
2024 0

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144 results

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Page 1
Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
Mengwasser KE, Adeyemi RO, Leng Y, Choi MY, Clairmont C, D'Andrea AD, Elledge SJ. Mengwasser KE, et al. Among authors: elledge sj. Mol Cell. 2019 Mar 7;73(5):885-899.e6. doi: 10.1016/j.molcel.2018.12.008. Epub 2019 Jan 24. Mol Cell. 2019. PMID: 30686591 Free PMC article.
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.
Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ. Meerbrey KL, et al. Among authors: elledge sj. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3665-70. doi: 10.1073/pnas.1019736108. Epub 2011 Feb 9. Proc Natl Acad Sci U S A. 2011. PMID: 21307310 Free PMC article.
RNA interference.
Hannon GJ. Hannon GJ. Nature. 2002 Jul 11;418(6894):244-51. doi: 10.1038/418244a. Nature. 2002. PMID: 12110901 Review.
A conserved biological response to double-stranded RNA, known variously as RNA interference (RNAi) or post-transcriptional gene silencing, mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protei …
A conserved biological response to double-stranded RNA, known variously as RNA interference (RNAi) or post-transcriptional gen …
Lessons from Nature: microRNA-based shRNA libraries.
Chang K, Elledge SJ, Hannon GJ. Chang K, et al. Among authors: hannon gj, elledge sj. Nat Methods. 2006 Sep;3(9):707-14. doi: 10.1038/nmeth923. Nat Methods. 2006. PMID: 16929316 Review.
In many systems, technologies allowing the use of such approaches were lacking before the discovery of RNA interference (RNAi). We have constructed first-generation short hairpin RNA (shRNA) libraries modeled after precursor microRNAs (miRNAs) and second-generation …
In many systems, technologies allowing the use of such approaches were lacking before the discovery of RNA interference (RNAi) …
RNAi: an ever-growing puzzle.
Denli AM, Hannon GJ. Denli AM, et al. Among authors: hannon gj. Trends Biochem Sci. 2003 Apr;28(4):196-201. doi: 10.1016/S0968-0004(03)00058-6. Trends Biochem Sci. 2003. PMID: 12713903 Review.
In recent years, sequence-specific gene silencing has been an area of increasing focus, both because of its interesting biology and because of its power as an experimental tool. A growing understanding of one such phenomenon, RNA interference (RNAi), has provided cl …
In recent years, sequence-specific gene silencing has been an area of increasing focus, both because of its interesting biology and because …
Asparagine bioavailability governs metastasis in a model of breast cancer.
Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ. Knott SRV, et al. Among authors: hannon gj. Nature. 2018 Feb 15;554(7692):378-381. doi: 10.1038/nature25465. Epub 2018 Feb 7. Nature. 2018. PMID: 29414946 Free PMC article.
A combination of differential expression and focused in vitro and in vivo RNA interference screens revealed candidate drivers of metastasis that discriminated metastatic clones. ...
A combination of differential expression and focused in vitro and in vivo RNA interference screens revealed candidate drivers …
The rest is silence.
Bernstein E, Denli AM, Hannon GJ. Bernstein E, et al. Among authors: hannon gj. RNA. 2001 Nov;7(11):1509-21. RNA. 2001. PMID: 11720281 Free PMC article. Review.
What has become abundantly clear is that the complex and highly conserved biology underlying RNA interference is critical both for genome maintenance and for the development of complex organisms. ...
What has become abundantly clear is that the complex and highly conserved biology underlying RNA interference is critical both …
Ancestral roles of small RNAs: an Ago-centric perspective.
Joshua-Tor L, Hannon GJ. Joshua-Tor L, et al. Among authors: hannon gj. Cold Spring Harb Perspect Biol. 2011 Oct 1;3(10):a003772. doi: 10.1101/cshperspect.a003772. Cold Spring Harb Perspect Biol. 2011. PMID: 20810548 Free PMC article. Review.
miRNAs on the move: miRNA biogenesis and the RNAi machinery.
Murchison EP, Hannon GJ. Murchison EP, et al. Among authors: hannon gj. Curr Opin Cell Biol. 2004 Jun;16(3):223-9. doi: 10.1016/j.ceb.2004.04.003. Curr Opin Cell Biol. 2004. PMID: 15145345 Review.
Recent advances have led to a more detailed understanding of RNA interference and its role in microRNA biogenesis and function. ...The 3' two-nucleotide overhang structure, a signature of RNaseIII cleavage, has been identified as a critical specificity determinant i …
Recent advances have led to a more detailed understanding of RNA interference and its role in microRNA biogenesis and function …
Conserved themes in small-RNA-mediated transposon control.
Girard A, Hannon GJ. Girard A, et al. Among authors: hannon gj. Trends Cell Biol. 2008 Mar;18(3):136-48. doi: 10.1016/j.tcb.2008.01.004. Epub 2008 Feb 20. Trends Cell Biol. 2008. PMID: 18282709 Free PMC article. Review.
144 results