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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1973 1
1976 3
1978 4
1979 2
1980 5
1981 4
1982 7
1983 9
1984 6
1985 10
1986 7
1987 12
1988 8
1989 21
1990 24
1991 13
1992 21
1993 19
1994 26
1995 24
1996 25
1997 31
1998 31
1999 26
2000 40
2001 19
2002 28
2003 38
2004 31
2005 42
2006 37
2007 43
2008 53
2009 41
2010 36
2011 39
2012 44
2013 46
2014 45
2015 42
2016 40
2017 35
2018 49
2019 45
2020 52
2021 62
2022 46
2023 38
2024 19

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1,253 results

Results by year

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Page 1
Immunosenescence: a key player in cancer development.
Lian J, Yue Y, Yu W, Zhang Y. Lian J, et al. J Hematol Oncol. 2020 Nov 10;13(1):151. doi: 10.1186/s13045-020-00986-z. J Hematol Oncol. 2020. PMID: 33168037 Free PMC article. Review.
Immunosenescence is a process of immune dysfunction that occurs with age and includes remodeling of lymphoid organs, leading to changes in the immune function of the elderly, which is closely related to the development of infections, autoimmune diseases, and malignant tumors. …
Immunosenescence is a process of immune dysfunction that occurs with age and includes remodeling of lymphoid organs, leading to changes in t …
PD-1 and PD-L1 in cancer immunotherapy: clinical implications and future considerations.
Jiang Y, Chen M, Nie H, Yuan Y. Jiang Y, et al. Hum Vaccin Immunother. 2019;15(5):1111-1122. doi: 10.1080/21645515.2019.1571892. Epub 2019 Mar 19. Hum Vaccin Immunother. 2019. PMID: 30888929 Free PMC article. Review.
Programmed death-1 (PD-1) is a cell surface receptor that functions as a T cell checkpoint and plays a central role in regulating T cell exhaustion. Binding of PD-1 to its ligand, programmed death-ligand 1 (PD-L1), activates downstream signaling …
Programmed death-1 (PD-1) is a cell surface receptor that functions as a T cell checkpoint and plays a central role in regulat …
B7-H4, a promising target for immunotherapy.
Wang JY, Wang WP. Wang JY, et al. Cell Immunol. 2020 Jan;347:104008. doi: 10.1016/j.cellimm.2019.104008. Epub 2019 Nov 4. Cell Immunol. 2020. PMID: 31733822 Review.
The coinhibitory molecule B7-H4, an important member of the B7 family, is abnormally expressed in tumors, inflammation and autoimmune diseases. B7-H4 negatively regulates T cell immune response and promotes immune escape by inhibiting the proliferation, cytok …
The coinhibitory molecule B7-H4, an important member of the B7 family, is abnormally expressed in tumors, inflammation and autoimmune …
The Role of Immunometabolism in the Pathogenesis of Systemic Lupus Erythematosus.
Robinson GA, Wilkinson MGL, Wincup C. Robinson GA, et al. Front Immunol. 2022 Jan 26;12:806560. doi: 10.3389/fimmu.2021.806560. eCollection 2021. Front Immunol. 2022. PMID: 35154082 Free PMC article. Review.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder in which pathogenic abnormalities within both the innate and adaptive immune response have been described. In order to activated, proliferate and maintain this immunological response a drastic upreg …
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder in which pathogenic abnormalities within both the innate and adap …
An update on the pathophysiology of immune thrombocytopenia.
Semple JW, Rebetz J, Maouia A, Kapur R. Semple JW, et al. Curr Opin Hematol. 2020 Nov;27(6):423-429. doi: 10.1097/MOH.0000000000000612. Curr Opin Hematol. 2020. PMID: 32868673 Review.
PURPOSE OF REVIEW: To summarize the literature relating to the pathophysiology of ITP including the working mechanisms of therapies, T-cell and B-cell physiology, protein/RNA/DNA biochemistry, and animal models in an attempt to unify the perceived abnormal im …
PURPOSE OF REVIEW: To summarize the literature relating to the pathophysiology of ITP including the working mechanisms of therapies, T …
HBV-Induced Immune Imbalance in the Development of HCC.
Chen Y, Tian Z. Chen Y, et al. Front Immunol. 2019 Aug 27;10:2048. doi: 10.3389/fimmu.2019.02048. eCollection 2019. Front Immunol. 2019. PMID: 31507621 Free PMC article. Review.
Recently, the immunopathogenic mechanisms were described in mouse HBV-induced HCC models, which is absolutely dependent on the presence of HBV-specific T cell response and NK cell-derived IFN-gamma, findings which are consistent with the observations from CHB and HC …
Recently, the immunopathogenic mechanisms were described in mouse HBV-induced HCC models, which is absolutely dependent on the presence of H …
CD4 T cells: fates, functions, and faults.
Zhu J, Paul WE. Zhu J, et al. Blood. 2008 Sep 1;112(5):1557-69. doi: 10.1182/blood-2008-05-078154. Blood. 2008. PMID: 18725574 Free PMC article. Review.
Our understanding of the importance of the distinct differentiated forms of CD4 T cells and of the mechanisms through which they achieve their differentiated state has greatly expanded over the past 2 decades. Today at least 4 distinct CD4 T-cell subsets have been s …
Our understanding of the importance of the distinct differentiated forms of CD4 T cells and of the mechanisms through which they achieve the …
CD38: An important regulator of T cell function.
Li W, Liang L, Liao Q, Li Y, Zhou Y. Li W, et al. Biomed Pharmacother. 2022 Sep;153:113395. doi: 10.1016/j.biopha.2022.113395. Epub 2022 Jul 11. Biomed Pharmacother. 2022. PMID: 35834988 Free article. Review.
Thus, CD38-NAD(+) axis has a profound effect on T cell activity. In this paper, we reviewed the role and mechanism of CD38(+) CD4(+) T cells / CD38(+) CD8(+) T cells in cellular immunity and the effects of the CD38-NAD(+) axis on T cell activ …
Thus, CD38-NAD(+) axis has a profound effect on T cell activity. In this paper, we reviewed the role and mechanism of C …
Lipids in the tumor microenvironment: From cancer progression to treatment.
Corn KC, Windham MA, Rafat M. Corn KC, et al. Prog Lipid Res. 2020 Nov;80:101055. doi: 10.1016/j.plipres.2020.101055. Epub 2020 Aug 11. Prog Lipid Res. 2020. PMID: 32791170 Free PMC article. Review.
Over the past decade, the study of metabolic abnormalities in cancer cells has risen dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and nutrient-deplete tumor microenvironment or a distant tissue following metastasis. ...Lipid metaboli …
Over the past decade, the study of metabolic abnormalities in cancer cells has risen dramatically. Cancer cells can thrive in challen …
Metabolic Control of Autoimmunity and Tissue Inflammation in Rheumatoid Arthritis.
Qiu J, Wu B, Goodman SB, Berry GJ, Goronzy JJ, Weyand CM. Qiu J, et al. Front Immunol. 2021 Apr 2;12:652771. doi: 10.3389/fimmu.2021.652771. eCollection 2021. Front Immunol. 2021. PMID: 33868292 Free PMC article. Review.
HLA class II genes confer the strongest genetic risk to develop RA. They encode for molecules essential in the activation and differentiation of T cells, placing T cells upstream in the immunopathology. ...The metabolic signature of RA T cells is characterized by the shunt …
HLA class II genes confer the strongest genetic risk to develop RA. They encode for molecules essential in the activation and differe …
1,253 results