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Inherited disorders of complement.
Guenther LC. Guenther LC. J Am Acad Dermatol. 1983 Dec;9(6):815-39. doi: 10.1016/s0190-9622(83)70195-7. J Am Acad Dermatol. 1983. PMID: 6315788 Review.
Isolated complement component deficiencies are uncommon. Deficiencies of all eleven components and two inhibitors of the classical pathway have been described. ...The complement system and its associated biologic activities are reviewed. ...
Isolated complement component deficiencies are uncommon. Deficiencies of all eleven components and two inhibitors of the class …
Deficiency of the first component of human complement.
Reid KB. Reid KB. Immunodefic Rev. 1989;1(3):247-60. Immunodefic Rev. 1989. PMID: 2561058 Review.
C1 deficiency results from an absence or lowering of the level of one or more of the proteins C1q, C1r and C1s, which are the subcomponents of the C1 complex of the classical pathway of the serum complement system. ...Both acquired and genetic deficiencies of …
C1 deficiency results from an absence or lowering of the level of one or more of the proteins C1q, C1r and C1s, which are the …
Rheumatic syndromes associated with complement deficiency.
Barilla-LaBarca ML, Atkinson JP. Barilla-LaBarca ML, et al. Curr Opin Rheumatol. 2003 Jan;15(1):55-60. doi: 10.1097/00002281-200301000-00010. Curr Opin Rheumatol. 2003. PMID: 12496511 Review.
Deficiency of an early component of the classical complement pathway, C1q, C1r/C1s, C4, or C2, regularly produces autoimmunity in man, especially systemic lupus erythematosus. ...This review begins by summarizing the recognized autoimmune manifestation …
Deficiency of an early component of the classical complement pathway, C1q, C1r/C1s, C4, or C2, regularly produce …
Recurrent infections and staphylococcal liver abscess in a child with C1r deficiency.
Garty BZ, Conley ME, Douglas SD, Kolski GB. Garty BZ, et al. J Allergy Clin Immunol. 1987 Oct;80(4):631-5. doi: 10.1016/0091-6749(87)90018-2. J Allergy Clin Immunol. 1987. PMID: 3312373 Review.
Complete absence of the C1r portion of the first component of complement was found in a 2 1/2-year-old boy of Puerto Rican origin who presented with a staphylococcal liver abscess. His medical history also included two episodes of pneumonia complicated by a pneumato …
Complete absence of the C1r portion of the first component of complement was found in a 2 1/2-year-old boy of Puerto Rican ori …
Hereditary and acquired deficiencies of C1 inhibitor.
Davis AE 3rd. Davis AE 3rd. Immunodefic Rev. 1989;1(3):207-26. Immunodefic Rev. 1989. PMID: 2698641 Review.
C1 INH is the only plasma protease inhibitor of activated C1r and C1s, the serine protease subcomponents of the first complement component. ...Hereditary angioneurotic edema (HANE) occurs in individuals heterozygous for deficiency of C1 INH. Most patie …
C1 INH is the only plasma protease inhibitor of activated C1r and C1s, the serine protease subcomponents of the first complement …