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Year Number of Results
1978 1
1981 1
1983 2
1984 3
1985 3
1987 1
1989 1
1991 1
1993 1
1994 3
1995 1
1996 2
1997 2
1998 2
1999 2
2000 3
2001 3
2002 3
2003 6
2004 3
2007 1
2008 4
2009 3
2010 1
2011 4
2012 1
2014 2
2015 4
2016 1
2017 1
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2020 4
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2022 1
2023 1
2024 1

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71 results

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Page 1
Factor X deficiency.
Menegatti M, Peyvandi F. Menegatti M, et al. Semin Thromb Hemost. 2009 Jun;35(4):407-15. doi: 10.1055/s-0029-1225763. Epub 2009 Jul 13. Semin Thromb Hemost. 2009. PMID: 19598069 Review.
Factor X (FX) deficiency is a rare, recessively inherited bleeding disorder representing 10% of all rare bleeding diseases and affecting 1 in every 1,000,000 people. ...Phenotype diagnosis is based on the concomitant prolongation of the prothrombin time and
Factor X (FX) deficiency is a rare, recessively inherited bleeding disorder representing 10% of all rare bleeding disea
Protein C.
Esmon CT. Esmon CT. Prog Hemost Thromb. 1984;7:25-54. Prog Hemost Thromb. 1984. PMID: 6099583 Review.
Once activated, protein C has an almost total dependence on protein S to express anticoagulant activity. (98) This suggests that deficiencies of protein S may also be associated with thrombotic tendencies. ...What role does beta-hydroxyaspartic acid play in p …
Once activated, protein C has an almost total dependence on protein S to express anticoagulant activity. (98) This suggests th …
Computationally Driven Discovery in Coagulation.
Link KG, Stobb MT, Monroe DM, Fogelson AL, Neeves KB, Sindi SS, Leiderman K. Link KG, et al. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):79-86. doi: 10.1161/ATVBAHA.120.314648. Epub 2020 Oct 29. Arterioscler Thromb Vasc Biol. 2021. PMID: 33115272 Free PMC article. Review.
The mathematical model was used further to propose a potential mechanism for these observations whereby thrombin generation is rescued in FVIII-deficient plasma due to reduced substrate competition between FV and FVIII for FXa (activated factor X)....
The mathematical model was used further to propose a potential mechanism for these observations whereby thrombin generation is rescued in FV …
Complex history of the discovery and characterization of congenital factor X deficiency.
Girolami A, Cosi E, Sambado L, Girolami B, Randi ML. Girolami A, et al. Semin Thromb Hemost. 2015 Jun;41(4):359-65. doi: 10.1055/s-0034-1544000. Epub 2015 Apr 14. Semin Thromb Hemost. 2015. PMID: 25875733 Review.
Factor X (FX) plays a pivotal role in blood coagulation. FX represents the point where all coagulation systems converge and, once activated, it converts prothrombin into thrombin. ...All these studies have informed on the great heterogeneity and complexity of
Factor X (FX) plays a pivotal role in blood coagulation. FX represents the point where all coagulation systems converge and, o
The use of prophylaxis in the treatment of rare bleeding disorders.
Shapiro A. Shapiro A. Thromb Res. 2020 Dec;196:590-602. doi: 10.1016/j.thromres.2019.07.014. Epub 2019 Jul 19. Thromb Res. 2020. PMID: 31420204 Review.
Rare bleeding disorders (RBDs) are a heterogeneous group of coagulation factor deficiencies that include fibrinogen, prothrombin, alpha(2)-antiplasmin, plasminogen activator inhibitor-1, and factors II, V, V/VIII, VII, X, XI and XIII. ...Rapid treatment of bleeding …
Rare bleeding disorders (RBDs) are a heterogeneous group of coagulation factor deficiencies that include fibrinogen, prothrombin, alp …
Diagnosis, clinical manifestations and management of rare bleeding disorders in Iran.
Dorgalaleh A, Alavi SE, Tabibian S, Soori S, Moradi E, Bamedi T, Asadi M, Jalalvand M, Shamsizadeh M. Dorgalaleh A, et al. Hematology. 2017 May;22(4):224-230. doi: 10.1080/10245332.2016.1263007. Epub 2016 Nov 28. Hematology. 2017. PMID: 27894217 Review.
RESULTS AND DISCUSSION: Iran has the highest global incidence of factor XIII deficiency. Factor VII deficiency also is common in Iran, while factor II deficiency, with a prevalence of 1 per 3 million, is the rarest form of RBDs. Factor activity is avai …
RESULTS AND DISCUSSION: Iran has the highest global incidence of factor XIII deficiency. Factor VII deficiency also is common …
Coagulation, Protease-Activated Receptors, and Diabetic Kidney Disease: Lessons from eNOS-Deficient Mice.
Oe Y, Miyazaki M, Takahashi N. Oe Y, et al. Tohoku J Exp Med. 2021 Sep;255(1):1-8. doi: 10.1620/tjem.255.1. Tohoku J Exp Med. 2021. PMID: 34511578 Free article. Review.
In the extrinsic coagulation cascade, the tissue factor (factor III) and downstream coagulation factors, such as active factor X (FXa), exacerbate inflammation through activation of the protease-activated receptors (PARs). ...
In the extrinsic coagulation cascade, the tissue factor (factor III) and downstream coagulation factors, such as active factor
The factor VIII/von Willebrand factor complex: basic and clinical issues.
Federici AB. Federici AB. Haematologica. 2003 Jun;88(6):EREP02. Haematologica. 2003. PMID: 12826528 Review.
Factor VIIII (FVIII) and von Willebrand factor (VWF) are two distinct but related glycoproteins that circulate in plasma as a tightly bound complex (FVIII/VWF). Their deficiencies or structural defects are responsible for the most common inherited bleeding disorders, namel …
Factor VIIII (FVIII) and von Willebrand factor (VWF) are two distinct but related glycoproteins that circulate in plasma as a tightly bound …
Emicizumab: a novel drug in hemophilia A prophylaxis - a narrative review.
Mazurkiewicz Ł, Czernikiewicz K, Rupa-Matysek J, Gil L. Mazurkiewicz Ł, et al. Expert Rev Hematol. 2022 Oct;15(10):933-942. doi: 10.1080/17474086.2022.2131526. Epub 2022 Oct 16. Expert Rev Hematol. 2022. PMID: 36191306 Review.
INTRODUCTION: Hemophilia A is a genetically conditioned disease leading to hemostatic disorders due to factor VIII (FVIII) deficiency. The treatment of hemophilia has evolved throughout the past years and has significantly changed. One of the newest drugs for prophylactic …
INTRODUCTION: Hemophilia A is a genetically conditioned disease leading to hemostatic disorders due to factor VIII (FVIII) deficiency
Mesenchymal cell differentiation and diseases: involvement of translin/TRAX complexes and associated proteins.
Kasai M, Ishida R, Nakahara K, Okumura K, Aoki K. Kasai M, et al. Ann N Y Acad Sci. 2018 Jun;1421(1):37-45. doi: 10.1111/nyas.13690. Epub 2018 May 8. Ann N Y Acad Sci. 2018. PMID: 29740830 Review.
Translin and translin-associated factor X (translin/TRAX) proteins have been implicated in a variety of cellular activities central to nucleic acid metabolism. ...Significant progress has been made in understanding the roles of translin/TRAX complexes in RNA …
Translin and translin-associated factor X (translin/TRAX) proteins have been implicated in a variety of cellular activities
71 results