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The Fanconi anemia pathway limits the severity of mutagenesis.
Hinz JM, Nham PB, Salazar EP, Thompson LH. Hinz JM, et al. DNA Repair (Amst). 2006 Aug 13;5(8):875-84. doi: 10.1016/j.dnarep.2006.05.039. Epub 2006 Jul 11. DNA Repair (Amst). 2006. PMID: 16815103 Review.
Fanconi anemia (FA) is a developmental and cancer predisposition disorder in which key, yet unknown, physiological events promoting chromosome stability are compromised. ...
Fanconi anemia (FA) is a developmental and cancer predisposition disorder in which key, yet unknown, physiological events prom
Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.
Thompson LH, Hinz JM. Thompson LH, et al. Mutat Res. 2009 Jul 31;668(1-2):54-72. doi: 10.1016/j.mrfmmm.2009.02.003. Epub 2009 Feb 21. Mutat Res. 2009. PMID: 19622404 Free PMC article. Review.
The Fanconi anemia (FA) molecular network consists of 15 "FANC" proteins, of which 13 are associated with mutations in patients with this cancer-prone chromosome instability disorder. ...
The Fanconi anemia (FA) molecular network consists of 15 "FANC" proteins, of which 13 are associated with mutations in patient …
Fanconi anemia (cross)linked to DNA repair.
Niedernhofer LJ, Lalai AS, Hoeijmakers JH. Niedernhofer LJ, et al. Cell. 2005 Dec 29;123(7):1191-8. doi: 10.1016/j.cell.2005.12.009. Cell. 2005. PMID: 16377561 Free article. Review.
Fanconi anemia is characterized by hypersensitivity to DNA interstrand crosslinks (ICLs) and susceptibility to tumor formation. Despite the identification of numerous Fanconi anemia (FANC) genes, the mechanism by which proteins encoded by these genes p
Fanconi anemia is characterized by hypersensitivity to DNA interstrand crosslinks (ICLs) and susceptibility to tumor formation