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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
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1983 2
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1985 1
1986 1
1988 4
1989 7
1990 8
1991 10
1992 16
1993 12
1994 34
1995 44
1996 69
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1999 58
2000 52
2001 48
2002 55
2003 43
2004 50
2005 70
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2007 60
2008 52
2009 53
2010 74
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2024 9

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1,741 results

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Page 1
[Lynch syndrome: What is new?].
Pellat A, Netter J, Perkins G, Cohen R, Coulet F, Parc Y, Svrcek M, Duval A, André T. Pellat A, et al. Bull Cancer. 2019 Jul-Aug;106(7-8):647-655. doi: 10.1016/j.bulcan.2018.10.009. Epub 2018 Dec 4. Bull Cancer. 2019. PMID: 30527816 Free article. Review. French.
Therefore, it is characterized by the predisposition to a spectrum of cancers, primarily colorectal cancer (CRC) and endometrial cancer (EC). Lynch syndrome-related CRC accounts for 3% of all CRC. Lynch syndrome also accounts for 2% of all EC. I …
Therefore, it is characterized by the predisposition to a spectrum of cancers, primarily colorectal cancer (CRC) and endometrial canc …
Recent advances in Lynch syndrome.
Biller LH, Syngal S, Yurgelun MB. Biller LH, et al. Fam Cancer. 2019 Apr;18(2):211-219. doi: 10.1007/s10689-018-00117-1. Fam Cancer. 2019. PMID: 30627969 Free PMC article. Review.
Lynch syndrome is one of the most common hereditary cancer predisposition syndromes and is associated with increased risks of colorectal and endometrial cancer, as well as multiple other cancer types. ...This progress report aims to review some of the …
Lynch syndrome is one of the most common hereditary cancer predisposition syndromes and is associated with increased ri …
Identification of Lynch Syndrome.
Maratt JK, Stoffel E. Maratt JK, et al. Gastrointest Endosc Clin N Am. 2022 Jan;32(1):45-58. doi: 10.1016/j.giec.2021.09.002. Gastrointest Endosc Clin N Am. 2022. PMID: 34798986 Review.
Lynch syndrome (LS) is an autosomal dominant hereditary cancer syndrome caused by pathogenic germline variants (PGV) in any of the 4 DNA mismatch repair (MMR) genes, MLH1, MSH2, MSH6, and PMS2, or deletions in EPCAM. LS leads to an increased risk of in …
Lynch syndrome (LS) is an autosomal dominant hereditary cancer syndrome caused by pathogenic germline variants ( …
Hereditary Colorectal Cancer.
Hampel H, Kalady MF, Pearlman R, Stanich PP. Hampel H, et al. Hematol Oncol Clin North Am. 2022 Jun;36(3):429-447. doi: 10.1016/j.hoc.2022.02.002. Epub 2022 May 13. Hematol Oncol Clin North Am. 2022. PMID: 35577708 Review.
Some of these variants are in cancer genes that are associated with colorectal cancer while others are not. The hereditary colorectal cancer syndromes can be divided into two major categories, the nonpolyposis and the polyposis conditions. The nonpo …
Some of these variants are in cancer genes that are associated with colorectal cancer while others are not. The hereditary …
Lynch Syndrome-Associated Colorectal Cancer.
Sinicrope FA. Sinicrope FA. N Engl J Med. 2018 Aug 23;379(8):764-773. doi: 10.1056/NEJMcp1714533. N Engl J Med. 2018. PMID: 30134129 Review. No abstract available.
Lynch Syndrome and MSI-H Cancers: From Mechanisms to "Off-The-Shelf" Cancer Vaccines.
Roudko V, Cimen Bozkus C, Greenbaum B, Lucas A, Samstein R, Bhardwaj N. Roudko V, et al. Front Immunol. 2021 Sep 24;12:757804. doi: 10.3389/fimmu.2021.757804. eCollection 2021. Front Immunol. 2021. PMID: 34630437 Free PMC article. Review.
Defective DNA mismatch repair (dMMR) is associated with many cancer types including colon, gastric, endometrial, ovarian, hepatobiliary tract, urinary tract, brain and skin cancers. Lynch syndrome - a hereditary cause of dMMR - confers increased lifetime risk …
Defective DNA mismatch repair (dMMR) is associated with many cancer types including colon, gastric, endometrial, ovarian, hepatobiliary trac …
Microsatellite instability in colorectal cancer.
De' Angelis GL, Bottarelli L, Azzoni C, De' Angelis N, Leandro G, Di Mario F, Gaiani F, Negri F. De' Angelis GL, et al. Acta Biomed. 2018 Dec 17;89(9-S):97-101. doi: 10.23750/abm.v89i9-S.7960. Acta Biomed. 2018. PMID: 30561401 Free PMC article. Review.
MSI is recognized as one of the major carcinogenetic pathways of colorectal cancer (CRC): it represents a molecular hallmark of hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome (LS); moreover it is detected …
MSI is recognized as one of the major carcinogenetic pathways of colorectal cancer (CRC): it represents a molecular hallmark of he …
Pathology and genetics of hereditary colorectal cancer.
Ma H, Brosens LAA, Offerhaus GJA, Giardiello FM, de Leng WWJ, Montgomery EA. Ma H, et al. Pathology. 2018 Jan;50(1):49-59. doi: 10.1016/j.pathol.2017.09.004. Epub 2017 Nov 21. Pathology. 2018. PMID: 29169633 Review.
Colorectal cancer (CRC) accounts for over 8% of all deaths annually worldwide. Between 2 and 5% of all CRCs occur due to inherited syndromes, including Lynch syndrome, familial adenomatous polyposis, MUTYH-associated polyposis, Peutz-Jeghers syndrome, …
Colorectal cancer (CRC) accounts for over 8% of all deaths annually worldwide. Between 2 and 5% of all CRCs occur due to inherited sy …
Molecular pathology of Lynch syndrome.
Cerretelli G, Ager A, Arends MJ, Frayling IM. Cerretelli G, et al. J Pathol. 2020 Apr;250(5):518-531. doi: 10.1002/path.5422. J Pathol. 2020. PMID: 32141610 Review.
Lynch syndrome (LS) is characterised by predisposition to colorectal, endometrial, and other cancers and is caused by inherited pathogenic variants affecting the DNA mismatch repair (MMR) genes MLH1, MSH2, MSH6, and PMS2. ...Resources such as the Internationa …
Lynch syndrome (LS) is characterised by predisposition to colorectal, endometrial, and other cancers and is caused by i …
Recent Advances in Lynch Syndrome: Diagnosis, Treatment, and Cancer Prevention.
Yurgelun MB, Hampel H. Yurgelun MB, et al. Am Soc Clin Oncol Educ Book. 2018 May 23;38:101-109. doi: 10.1200/EDBK_208341. Am Soc Clin Oncol Educ Book. 2018. PMID: 30231390 Free article. Review.
In the 25 years since the discovery of microsatellite instability (MSI) and the first recognition of germline mismatch repair (MMR) gene variants as the etiologic basis of Lynch syndrome, there has been tremendous progress in the understanding of the spectrum of can …
In the 25 years since the discovery of microsatellite instability (MSI) and the first recognition of germline mismatch repair (MMR) gene var …
1,741 results