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Twenty-seven Years of Cerebral Pyruvate Recycling.
Cerdán S. Cerdán S. Neurochem Res. 2017 Jun;42(6):1621-1628. doi: 10.1007/s11064-017-2173-4. Epub 2017 Jan 18. Neurochem Res. 2017. PMID: 28101749 Review.
Cerebral pyruvate recycling is a metabolic pathway deriving carbon skeletons and reducing equivalents from mitochondrial oxaloacetate and malate, to the synthesis of mitochondrial and cytosolic pyruvate, lactate and alanine. ...At the cellular level, pyruvate …
Cerebral pyruvate recycling is a metabolic pathway deriving carbon skeletons and reducing equivalents from mitochondrial oxalo …
Mitochondrial thiols in the regulation of cell death pathways.
Yin F, Sancheti H, Cadenas E. Yin F, et al. Antioxid Redox Signal. 2012 Dec 15;17(12):1714-27. doi: 10.1089/ars.2012.4639. Epub 2012 Jun 11. Antioxid Redox Signal. 2012. PMID: 22530585 Free PMC article. Review.
RECENT ADVANCES: The energy component of this mitochondrial energy-redox axis entails the formation of reducing equivalents and their flow through the respiratory chain with the consequent electron leak to generate [Formula: see text] and H(2)O(2). ...The ultimate r …
RECENT ADVANCES: The energy component of this mitochondrial energy-redox axis entails the formation of reducing equivalents an …
The roles of NADPH and isocitrate dehydrogenase in cochlear mitochondrial antioxidant defense and aging.
White K, Someya S. White K, et al. Hear Res. 2023 Jan;427:108659. doi: 10.1016/j.heares.2022.108659. Epub 2022 Nov 24. Hear Res. 2023. PMID: 36493529 Review.
All cells possess antioxidant defense systems that play an important role in protecting cells against these factors. Reduced nicotinamide adenine dinucleotide phosphate (NADPH) serves as a co-factor for antioxidant enzymes such as glutathione reductase and thioredox …
All cells possess antioxidant defense systems that play an important role in protecting cells against these factors. Reduced nicotina …
Malic enzyme 2 as a potential therapeutic drug target for cancer.
Sarfraz I, Rasul A, Hussain G, Hussain SM, Ahmad M, Nageen B, Jabeen F, Selamoglu Z, Ali M. Sarfraz I, et al. IUBMB Life. 2018 Nov;70(11):1076-1083. doi: 10.1002/iub.1930. Epub 2018 Aug 29. IUBMB Life. 2018. PMID: 30160039 Free article. Review.
The aberrant expression pattern of enzymatic machineries orchestrates metabolic activities into a platform that ultimately promotes cellular growth, survival, and proliferation. The NADP(+)-dependent mitochondrial malic enzyme 2 (ME2) has been widely apprecia …
The aberrant expression pattern of enzymatic machineries orchestrates metabolic activities into a platform that ultimately promotes cellular …
The effect of nitric-oxide-related supplements on human performance.
Bescós R, Sureda A, Tur JA, Pons A. Bescós R, et al. Sports Med. 2012 Feb 1;42(2):99-117. doi: 10.2165/11596860-000000000-00000. Sports Med. 2012. PMID: 22260513 Review.
This labile molecule plays an important role in many functions in the body regulating vasodilatation, blood flow, mitochondrial respiration and platelet function. Currently, it is known that NO synthesis occurs via at least two physiological pathways: NO synthase (NOS) dep …
This labile molecule plays an important role in many functions in the body regulating vasodilatation, blood flow, mitochondrial respi …