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Primary immunodeficiencies of protective immunity to primary infections.
Clin Immunol. 2010 May;135(2):204-9. doi: 10.1016/j.clim.2010.02.001. Epub 2010 Mar 16.
Clin Immunol. 2010.
PMID: 20236864
Review.
The vast majority of primary immunodeficiencies (PIDs) predispose affected individuals to recurrent or chronic infectious diseases, because they affect protective immunity to both primary and secondary or latent infections. We discuss here three recently described groups o …
The vast majority of primary immunodeficiencies (PIDs) predispose affected individuals to recurrent or chronic infectious diseases, because …
Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IkappaBalpha deficiency.
Picard C, Casanova JL, Puel A.
Picard C, et al.
Clin Microbiol Rev. 2011 Jul;24(3):490-7. doi: 10.1128/CMR.00001-11.
Clin Microbiol Rev. 2011.
PMID: 21734245
Free PMC article.
Review.
Autosomal recessive IRAK-4 and MyD88 deficiencies predispose affected patients to recurrent invasive pyogenic bacterial infection. ...Both of these defects impair NF-kappaB-mediated cellular responses to multiple receptors, including TLRs, IL-1Rs, and tumor n …
Autosomal recessive IRAK-4 and MyD88 deficiencies predispose affected patients to recurrent invasive pyogenic bacterial …
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