News
Recent blog posts
Announcing the re-annotation of RefSeq genome assemblies for E. coli and four other species!
We have re-annotated all RefSeq genomes for Escherichia coli, Mycobacterium tuberculosis, Bacillus subtilis, Acinetobacter pittii, and Campylobacter jejuni using the most recent release of PGAP. You will find that more genes now have gene symbols (e.g. recA). Your feedback indicated that the lack of symbols was an impediment to comparative analysis, so we hope that this improvement … Continue reading Announcing the re-annotation of RefSeq genome assemblies for E. coli and four other species!
Common Data Elements: Increasing FAIR Data Sharing
Guest post by Carolina Mendoza-Puccini, MD, CDE Program Officer, Division of Clinical Research, National Institute of Neurological Disorders and Stroke (NINDS) and Kenneth J. Wilkins, PhD, Mathematical Statistician, Biostatistics Program and Office of Clinical Research Support, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Previous posts published in Musings … Continue reading "Common Data Elements: Increasing FAIR Data Sharing"
June 30 Webinar: Using NCBI Datasets to download sequence and annotation for genomes and genes
Join us on June 30, 2021 at 12PM eastern time to learn how to use the new NCBI Datasets resource to find and download gene, genome and SARS-CoV-2 sequence and annotation. You will learn how to access these datasets through either the web interface or the new command-line tools that allow you to incorporate these data … Continue reading June 30 Webinar: Using NCBI Datasets to download sequence and annotation for genomes and genes
Research news
The White House Wants To Fight Climate Change And Help People. Cleveland Led The Way
The White House wants to fight climate change in ways that also remove economic and racial disparities. The city of Cleveland has a plan that describes what that might mean.
Morning People May Be at Lower Risk of Depression Than Night Owls
Going to bed early and waking up early may help to provide some protection against depression, a new study suggests.
NCBI databases
The most up-to-date set of SARS‑CoV‑2 nucleotide and protein sequences
A curated literature hub for the latest scientific information on COVID-19
Use our new Betacoronavirus database for SARS‑CoV‑2 genome sequence analysis
Literature
The World's largest repository of medical and scientific abstracts, full-text articles, books and reports
Books and reports
Ontology used for PubMed indexing
Books, journals and more in the NLM Collections
Scientific and medical abstracts/citations
Full-text journal articles
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Collected information about gene loci
Functional genomics studies
Gene expression and molecular abundance profiles
Homologous genes sets for selected organisms
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved protein domains
Protein sequences grouped by identity
Protein sequences
Models representing homologous proteins with a common function
Experimentally-determined biomolecular structures
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Genome assembly information
Museum, herbaria, and other biorepository collections
Biological projects providing data to NCBI
Descriptions of biological source materials
Genome sequencing projects by organism
DNA and RNA sequences
High-throughput sequence reads
Taxonomic classification and nomenclature
BLAST
A tool to find regions of similarity between biological sequences
Search nucleotide sequence databases
Search protein seqeuence databases
Search protein databases using a translated nucleotide query
Search translated nucleotide databases using a protein query
Find primers specific to your PCR template
Clinical
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Privately and publicly funded clinical studies conducted around the world
Human variations of clinical significance
Genotype/phenotype interaction studies
Short genetic variations
Genome structural variation studies
Genetic testing registry
Medical genetics literature and links
Online mendelian inheritance in man
PubChem
Repository of chemical information, molecular pathways, and tools for bioactivity screening
Bioactivity screening studies
Chemical information with structures, information and links
Molecular pathways with links to genes, proteins and chemicals
Deposited substance and chemical information