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PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

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Drug Therapy for Early Rheumatoid Arthritis

A Systematic Review Update

Donahue KE, Gartlehner G, Schulman ER, et al.

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Research news

NIH Research Matters MARCH 26, 2024

Talk therapy cuts risk of postpartum depression

An intervention given to pregnant women by non-specialist providers greatly reduced the chances of developing postpartum depression or anxiety.

NIH Research Matters MARCH 26, 2024

How excess niacin may promote cardiovascular disease

Findings about a metabolite of niacin, or vitamin B3, raise concerns about the health effects of too much niacin and suggest new measures to help prevent or treat cardiovascular disease

The Washington Post MARCH 26, 2024

Birds, bees and even plants might act weird during the solar eclipse

Carolyn Y. Johnson

A total eclipse isn’t just a spectacle in the sky. Birds, insects and even plants will take notice, and might start acting strange.

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Recent blog posts

NCBI Insights MARCH 28, 2024

MedGen Users, We Want Your Feedback!

Do you use NCBI’s MedGen? If so, then you probably know it’s NCBI’s one-stop-shop for genetic phenotype information. If you are a healthcare provider, genetic professional, researcher, or anyone who uses MedGen, we want to hear from you to help us make this resource better meet your needs!   We want to know:  How you currently … Continue reading MedGen Users, We Want Your Feedback!

NIH Director's Blog MARCH 28, 2024

Immune Checkpoint Discovery Has Implications for Treating Cancer and Autoimmune Diseases

Your immune system should ideally recognize and attack infectious invaders and cancerous cells. But the system requires safety mechanisms, or brakes, to keep it from damaging healthy cells. To do this, T cells—the immune system’s most powerful attackers—rely on immune “checkpoints” to turn immune activation down when they receive the right signal. While these interactions have been well studied, a research team supported in part by NIH has made an unexpected discovery into how a key immune checkpoint works, with potentially important implications for therapies designed to boost or dampen immune activity to treat cancer and autoimmune diseases.

NLM Musings MARCH 27, 2024

“Computers don’t diagnose the same way that doctors do” - NLM Lecture Explored How a Cancer Diagnosis Can Help Illustra…

How can cancer help us understand algorithmic bias? At this year’s NLM Science, Technology, and Society Lecture, journalist and AI ethics expert Meredith Broussard shared how her personal experience with breast cancer can help illuminate the potential impact that racial and gender bias can have on the use of AI in medical contexts.