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NIH Director's Blog TODAY

Dynamic View of Spike Protein Reveals Prime Targets for COVID-19 Treatments

This striking portrait features the spike protein that crowns SARS-CoV-2, the coronavirus that causes COVID-19. This highly flexible protein has settled here into one of its many possible conformations during the process of docking onto a human cell before infecting it.

NCBI Insights YESTERDAY

New RefSeq annotations for Siamese fighting fish, common toad, swan, platypus and more!

In March and April, the NCBI Eukaryotic Genome Annotation Pipeline released thirty-two new annotations in RefSeq for the following organisms: Aegilops tauschii (monocot) Amblyraja radiata (thorny skate) Anopheles arabiensis (mosquito) Anopheles coluzzii (mosquito) Bactrocera tryoni (Queensland fruit fly) Belonocnema kinseyi (wasp) Betta splendens (Siamese fighting fish) Bufo bufo (common toad) Cygnus olor (mute swan) Falco naumanni (lesser kestrel) …

NLM Musings YESTERDAY

Thank You, My Nurse Colleagues

Writing these blog posts gives me a chance to showcase some of the great work done by our team at NLM, and reflect on the roles I play as part of the NIH leadership team, Director of the National Library of Medicine, a mother-daughter-sister-aunt-friend, and an advocate for self-care management education and support for all …

Research news

The New York Times YESTERDAY

This New Covid Vaccine Could Bring Hope to the Unvaccinated World

The German company CureVac hopes its RNA vaccine will rival those made by Moderna and Pfizer-BioNTech. It could be ready next month.

NPR News MAY 4, 2021

Trees Talk To Each Other. 'Mother Tree' Ecologist Hears Lessons For People, Too

Ecologist Suzanne Simard says trees are "social creatures" that communicate with each other in remarkable ways — including warning each other of danger and sharing nutrients at critical times.

More news COVID-19 news

NCBI databases

NCBI Virus

The most up-to-date set of SARS‑CoV‑2 nucleotide and protein sequences

LitCovid

A curated literature hub for the latest scientific information on COVID-19

BLAST

Use our new Betacoronavirus database for SARS‑CoV‑2 genome sequence analysis

Literature

The World's largest repository of medical and scientific abstracts, full-text articles, books and reports

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

HomoloGene

Homologous genes sets for selected organisms

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Family Models

Models representing homologous proteins with a common function

Structure

Experimentally-determined biomolecular structures

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

BLAST

A tool to find regions of similarity between biological sequences

blastn

Search nucleotide sequence databases

blastp

Search protein seqeuence databases

blastx

Search protein databases using a translated nucleotide query

tblastn

Search translated nucleotide databases using a protein query

Primer-BLAST

Find primers specific to your PCR template

Clinical

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinicalTrials.gov

Privately and publicly funded clinical studies conducted around the world

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

PubChem

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioAssays

Bioactivity screening studies

Compounds

Chemical information with structures, information and links

Pathways

Molecular pathways with links to genes, proteins and chemicals

Substances

Deposited substance and chemical information