News
Recent blog posts
Dynamic View of Spike Protein Reveals Prime Targets for COVID-19 Treatments
This striking portrait features the spike protein that crowns SARS-CoV-2, the coronavirus that causes COVID-19. This highly flexible protein has settled here into one of its many possible conformations during the process of docking onto a human cell before infecting it.
New RefSeq annotations for Siamese fighting fish, common toad, swan, platypus and more!
In March and April, the NCBI Eukaryotic Genome Annotation Pipeline released thirty-two new annotations in RefSeq for the following organisms: Aegilops tauschii (monocot) Amblyraja radiata (thorny skate) Anopheles arabiensis (mosquito) Anopheles coluzzii (mosquito) Bactrocera tryoni (Queensland fruit fly) Belonocnema kinseyi (wasp) Betta splendens (Siamese fighting fish) Bufo bufo (common toad) Cygnus olor (mute swan) Falco naumanni (lesser kestrel) …
Thank You, My Nurse Colleagues
Writing these blog posts gives me a chance to showcase some of the great work done by our team at NLM, and reflect on the roles I play as part of the NIH leadership team, Director of the National Library of Medicine, a mother-daughter-sister-aunt-friend, and an advocate for self-care management education and support for all …
Research news
This New Covid Vaccine Could Bring Hope to the Unvaccinated World
The German company CureVac hopes its RNA vaccine will rival those made by Moderna and Pfizer-BioNTech. It could be ready next month.
Trees Talk To Each Other. 'Mother Tree' Ecologist Hears Lessons For People, Too
Ecologist Suzanne Simard says trees are "social creatures" that communicate with each other in remarkable ways — including warning each other of danger and sharing nutrients at critical times.
NCBI databases
The most up-to-date set of SARS‑CoV‑2 nucleotide and protein sequences
A curated literature hub for the latest scientific information on COVID-19
Use our new Betacoronavirus database for SARS‑CoV‑2 genome sequence analysis
Literature
The World's largest repository of medical and scientific abstracts, full-text articles, books and reports
Books and reports
Ontology used for PubMed indexing
Books, journals and more in the NLM Collections
Scientific and medical abstracts/citations
Full-text journal articles
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Collected information about gene loci
Functional genomics studies
Gene expression and molecular abundance profiles
Homologous genes sets for selected organisms
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved protein domains
Protein sequences grouped by identity
Protein sequences
Models representing homologous proteins with a common function
Experimentally-determined biomolecular structures
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Genome assembly information
Museum, herbaria, and other biorepository collections
Biological projects providing data to NCBI
Descriptions of biological source materials
Genome sequencing projects by organism
DNA and RNA sequences
High-throughput sequence reads
Taxonomic classification and nomenclature
BLAST
A tool to find regions of similarity between biological sequences
Search nucleotide sequence databases
Search protein seqeuence databases
Search protein databases using a translated nucleotide query
Search translated nucleotide databases using a protein query
Find primers specific to your PCR template
Clinical
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Privately and publicly funded clinical studies conducted around the world
Human variations of clinical significance
Genotype/phenotype interaction studies
Short genetic variations
Genome structural variation studies
Genetic testing registry
Medical genetics literature and links
Online mendelian inheritance in man
PubChem
Repository of chemical information, molecular pathways, and tools for bioactivity screening
Bioactivity screening studies
Chemical information with structures, information and links
Molecular pathways with links to genes, proteins and chemicals
Deposited substance and chemical information