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NCBI Insights TODAY

Announcing the re-annotation of RefSeq genome assemblies for E. coli and four other species!

We have re-annotated all RefSeq genomes for Escherichia coli, Mycobacterium tuberculosis, Bacillus subtilis, Acinetobacter pittii, and Campylobacter jejuni using the most recent release of PGAP. You will find that more genes now have gene symbols (e.g. recA). Your feedback indicated that the lack of symbols was an impediment to comparative analysis, so we hope that this improvement … Continue reading Announcing the re-annotation of RefSeq genome assemblies for E. coli and four other species!

NLM Musings TODAY

Common Data Elements: Increasing FAIR Data Sharing

Guest post by Carolina Mendoza-Puccini, MD, CDE Program Officer, Division of Clinical Research, National Institute of Neurological Disorders and Stroke (NINDS) and Kenneth J. Wilkins, PhD, Mathematical Statistician, Biostatistics Program and Office of Clinical Research Support, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Previous posts published in Musings … Continue reading "Common Data Elements: Increasing FAIR Data Sharing"

NCBI Insights YESTERDAY

June 30 Webinar: Using NCBI Datasets to download sequence and annotation for genomes and genes

Join us on June 30, 2021 at 12PM eastern time to learn how to use the new NCBI Datasets resource to find and download gene, genome and SARS-CoV-2 sequence and annotation. You will learn how to access these datasets through either the web interface or the new command-line tools that allow you to incorporate these data … Continue reading June 30 Webinar: Using NCBI Datasets to download sequence and annotation for genomes and genes

Research news

NPR News JUNE 21, 2021

The White House Wants To Fight Climate Change And Help People. Cleveland Led The Way

The White House wants to fight climate change in ways that also remove economic and racial disparities. The city of Cleveland has a plan that describes what that might mean.

The New York Times JUNE 21, 2021

Morning People May Be at Lower Risk of Depression Than Night Owls

Going to bed early and waking up early may help to provide some protection against depression, a new study suggests.

More news COVID-19 news

NCBI databases

NCBI Virus

The most up-to-date set of SARS‑CoV‑2 nucleotide and protein sequences

LitCovid

A curated literature hub for the latest scientific information on COVID-19

BLAST

Use our new Betacoronavirus database for SARS‑CoV‑2 genome sequence analysis

Literature

The World's largest repository of medical and scientific abstracts, full-text articles, books and reports

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

HomoloGene

Homologous genes sets for selected organisms

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Family Models

Models representing homologous proteins with a common function

Structure

Experimentally-determined biomolecular structures

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

BLAST

A tool to find regions of similarity between biological sequences

blastn

Search nucleotide sequence databases

blastp

Search protein seqeuence databases

blastx

Search protein databases using a translated nucleotide query

tblastn

Search translated nucleotide databases using a protein query

Primer-BLAST

Find primers specific to your PCR template

Clinical

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinicalTrials.gov

Privately and publicly funded clinical studies conducted around the world

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

PubChem

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioAssays

Bioactivity screening studies

Compounds

Chemical information with structures, information and links

Pathways

Molecular pathways with links to genes, proteins and chemicals

Substances

Deposited substance and chemical information