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News: Using viruses to treat... (NIH Research Matters) - Behind the headlines

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Media coverage of health and science topics

NIH Research Matters June 28, 2022

Using viruses to treat antibiotic-resistant bacterial infections

In several patients, treatment of bacterial lung infections with viruses called phages eliminated the infection.

Read more at NIH Research Matters

Behind the headlines

Research findings and data from the National Library of Medicine

PubMed articles

Cell MAY 26, 2022

Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection

JA Nick et al

Two mycobacteriophages were administered intravenously to a male with treatment-refractory Mycobacterium abscessus pulmonary infection and severe cystic fibrosis lung dis …

Clin Infect Dis JUNE 9, 2022

Phage Therapy of Mycobacterium Infections: Compassionate-use of Phages in Twenty Patients with Drug-Resistant Mycobacterial Disease

RM Dedrick et al

Phage treatment of Mycobacterium infections is challenging due to the limited repertoire of therapeutically useful phages, but favorable clinical outcomes in patients lac …

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NPR News MAY 8, 2019

Genetically Modified Viruses Help Save A Patient With A 'Superbug' Infection

Treatment with genetically altered bacteriophages — viruses that attack bacteria — may have halted a patient's near-fatal infection, hinting at new ways to fight antibiotic-resistant bacteria.

NIH Research Matters JUNE 4, 2019

Engineered phages treat drug-resistant infection

Engineered phages were used to treat a teenager’s life-threatening antibiotic-resistant infection. The approach could be used to combat otherwise untreatable infections.

The Scientist MAY 8, 2019

Genetically Modified Viral Cocktail Treats Deadly Bacteria in Teen

Tweaking the genomes of two phages and combining them with a third phage helped to clear a persistent Mycobacterium infection in the patient.

The Scientist JULY 19, 2018

CRISPR Is Overcome When Viruses Gang Up on Bacteria

Phages that die during bacterial invasion help other viruses defeat the microbes' immune responses.

The Guardian MAY 8, 2019

Teenager recovers from near death in world-first GM virus treatment

Bacteria-killing viruses known as phages offer hope of solution to antibiotic resistance