Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

News: A New Piece in the HIV Replication... (The Scientist) - Behind the headlines

In the news

Media coverage of health and science topics

The Scientist Feb. 14, 2024

A New Piece in the HIV Replication Puzzle

A host lipid-modifying enzyme plays a key role in HIV envelope formation, viral maturation, and infectivity. 

Read more at The Scientist

Behind the headlines

Research findings and data from the National Library of Medicine

PubMed articles

Proc Natl Acad Sci U S A JULY 11, 2023

Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound

SW Yoo et al

Although HIV-1 Gag is known to drive viral assembly and budding, the precise mechanisms by which the lipid composition of the plasma membrane is remodeled during assembly …

Ann Neurol JAN. 1, 2004

Perturbation of sphingolipid metabolism and ceramide production in HIV-dementia

NJ Haughey et al

Infection by the human immunodeficiency virus type 1 (HIV-1) often results in neurological dysfunction including HIV dementia (HIVD). Alterations in cytokine and redox ba …

Proc Natl Acad Sci U S A JULY 11, 2023

Neutral sphingomyelinase 2 is required for HIV-1 maturation

AA Waheed et al

HIV-1 assembly occurs at the inner leaflet of the plasma membrane (PM) in highly ordered membrane microdomains. The size and stability of membrane microdomains is regulat …

Related content

Similar articles


Also of interest

Additional recent and related news

The Scientist MAY 8, 2023

A New Smartphone Application Improves Memory Recall in Older Adults

Neuroscientists developed and tested a promising mobile app that mitigates age-related memory decline.

The Scientist JUNE 1, 2023

Mouse Brain Cells Activate When They Witness a Fight

A subset of hypothalamic neurons mirrors aggression in mice, challenging previous views on the location and functional role of these cells.

The Scientist SEPT. 8, 2023

Hair Turns Gray Due to Stuck Stem Cells

Hair-coloring stem cells must swing back and forth between their maturity states to give hair its color.

The Scientist SEPT. 8, 2023

When Microbes Meet the Immune System

Timothy Hand leads a research team that explores how maternal immune signals shape the infant intestinal microbiota.

The Scientist DEC. 4, 2023

Tracking Down Innate Immune Cells in Multiple Sclerosis

A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.