DataSet Record GDS3966: Expression Profiles Data Analysis Tools Sample Subsets
Title: Melanoma metastasis
Cluster AnalysisGDS3966 Cluster Image
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Summary: Analysis of melanoma clinical samples representing 31 primary melanomas and 52 melanoma metastases. These results, together with results from tumor samples from highly-metastatic derivatives of an A375 (ATCC) melanoma cell line, provide insight into the molecular basis of metastasis.
Organism: Homo sapiens
Platform: GPL96: [HG-U133A] Affymetrix Human Genome U133A Array
Citations:
  • Xu L, Shen SS, Hoshida Y, Subramanian A et al. Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Mol Cancer Res 2008 May;6(5):760-9. PMID: 18505921
  • Jalili A, Mertz KD, Romanov J, Wagner C et al. NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo. PLoS One 2013;8(7):e69064. PMID: 23935925
Reference Series: GSE8401 Sample count: 83
Value type: count Series published: 2007/10/02