DataSet Record GDS1027: Expression Profiles Data Analysis Tools Sample Subsets
Title: Sulfur mustard effect on lungs: dose response and time course
Cluster AnalysisGDS1027 Cluster Image
Summary: Analysis of lungs from Sprague Dawley males following injection with 1, 3, or 6 mg/kg of sulfur mustard (SM) bis-(2-chloroethyl) sulfide, a carcinogenic alkylating agent. Lungs examined at various time points up to 24 hours postinjection. Results provide insight into SM-induced lung injury.
Organism: Rattus norvegicus
Platform: GPL341: [RAE230A] Affymetrix Rat Expression 230A Array
  • Dillman JF 3rd, Phillips CS, Dorsch LM, Croxton MD et al. Genomic analysis of rodent pulmonary tissue following bis-(2-chloroethyl) sulfide exposure. Chem Res Toxicol 2005 Jan;18(1):28-34. PMID: 15651846
  • Yu X, Griffith WC, Hanspers K, Dillman JF 3rd et al. A system-based approach to interpret dose- and time-dependent microarray data: quantitative integration of gene ontology analysis for risk assessment. Toxicol Sci 2006 Aug;92(2):560-77. PMID: 16601082
Reference Series: GSE1888 Sample count: 154
Value type: count Series published: 2004/12/20