Inflammatory lung injury and mechanical ventilation
Summary:
Analysis of lungs of C57BL/6 based model of lung inflammation and injury. The model develops acute lung injury (ALI) after concurrent exposure to low-dose lipopolysaccharide (LPS) and mechanical ventilation (MV). MV may contribute to ALI in critically ill patients.
Altemeier WA, Matute-Bello G, Gharib SA, Glenny RW et al. Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation. J Immunol 2005 Sep 1;175(5):3369-76. PMID: 16116230
